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Questions and Answers

What is the most outer layer of compact bone called?

  • Periosteum (correct)
  • Endosteum
  • Epiphysis
  • Cortex
  • Which of the following statements is true regarding the relationship between lysosomes and cellular components?

  • Lysosomes are responsible for the synthesis of proteins in the cell.
  • Lysosomes help in the formation of the outer membrane of the cell.
  • Lysosomes primarily function to store nutrients within the cell.
  • Lysosomes are involved in the breakdown of waste materials and cellular debris. (correct)
  • How does the absence of water affect cellular processes?

  • It can lead to cellular dehydration and hinder metabolic reactions. (correct)
  • It improves the structural integrity of the cell.
  • It has no significant impact on cellular metabolism.
  • It enhances the efficiency of enzymatic reactions.
  • What is the fineermost layer of bone tissue primarily responsible for?

    <p>Houses blood vessels and nerves (C)</p> Signup and view all the answers

    What is the significance of compact bone structure in the skeletal system?

    <p>It provides strength and support for weight-bearing activities. (A)</p> Signup and view all the answers

    Flashcards

    Compact bone layer

    The dense, outer layer of compact bone.

    Network without water

    A network or system lacking water.

    Most outer layer of compact bone

    The outermost layer of compact bone.

    Fine, innermost bone layer

    The thin inner layer of compact bone.

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    Tyosomal

    Term related to a cell component, probably lysosome

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    Study Notes

    Bone Histology

    • Bone is a specialized connective tissue.
    • Its matrix is calcified for strength and support.
    • The main components are bone cells, fibers, and a hard matrix.

    Learning Objectives

    • Classify bone anatomically and histologically.
    • Identify the locations of compact and spongy bones.
    • Understand the microstructure of bone.

    Bone Classification

    • Anatomical: Long (humerus, femur), short (carpals, tarsals), flat (skull, ribs), irregular (vertebrae).
    • Histological: Compact and cancellous (spongy).

    Compact Bone

    • Dense, solid lamellae without cavities.
    • Located in the shaft of long bones.
    • Covers the plates of flat, short, and irregular bones.

    Cancellous (Spongy) Bone

    • Irregular branching, anastomosing trabeculae.
    • Encloses bone marrow cavities.
    • Found in the center of flat bones, short bones, irregular bones, and epiphyses of long bones.

    Bone Tissue Structure

    • Bone Cells:
      • Osteogenic cells (osteoprogenitor cells): precursor cells.
      • Osteoblasts: bone-forming cells; synthesize osteoid tissue.
      • Osteocytes: mature bone cells, maintain bone hardness.
      • Osteoclasts: large, multinucleated cells that resorb bone; found in Howship's lacunae.
    • Fibers: Collagen type I, forming the organic part of the bone matrix.
    • Ground Substance: GAGs & glycoproteins, without water.
    • Hydroxyapatite Crystals: Calcium salts, forming the inorganic part of the matrix.

    Histology of Compact Bone

    • Organizational Layers: Periosteum, external circumferential lamellae, Haversian system (osteon), interstitial lamellae, internal circumferential lamellae, and Endosteum.
    • Haversian System: Concentric lamellae surrounding a central canal (Haversian canal). Contains blood vessels, nerves, and connective tissue. Haversian canals communicate between the marrow cavity and periosteum through Volkmann's canals.

    Histology of Spongy Bone

    • Trabeculae: Irregular branching, anastomosing bony trabeculae.
    • Bone Marrow: Cavities enclosed by trabeculae.
    • Lamellae: Each trabeculum is formed of irregularly arranged bone lamellae, containing osteocytes. Spongy bone does not contain osteons.

    References

    • Junqueira's Basic Histology; 13th Edition, 2013, Anthony L. Mescher.

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