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Questions and Answers
What is the most outer layer of compact bone called?
What is the most outer layer of compact bone called?
Which of the following statements is true regarding the relationship between lysosomes and cellular components?
Which of the following statements is true regarding the relationship between lysosomes and cellular components?
How does the absence of water affect cellular processes?
How does the absence of water affect cellular processes?
What is the fineermost layer of bone tissue primarily responsible for?
What is the fineermost layer of bone tissue primarily responsible for?
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What is the significance of compact bone structure in the skeletal system?
What is the significance of compact bone structure in the skeletal system?
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Flashcards
Compact bone layer
Compact bone layer
The dense, outer layer of compact bone.
Network without water
Network without water
A network or system lacking water.
Most outer layer of compact bone
Most outer layer of compact bone
The outermost layer of compact bone.
Fine, innermost bone layer
Fine, innermost bone layer
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Tyosomal
Tyosomal
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Study Notes
Bone Histology
- Bone is a specialized connective tissue.
- Its matrix is calcified for strength and support.
- The main components are bone cells, fibers, and a hard matrix.
Learning Objectives
- Classify bone anatomically and histologically.
- Identify the locations of compact and spongy bones.
- Understand the microstructure of bone.
Bone Classification
- Anatomical: Long (humerus, femur), short (carpals, tarsals), flat (skull, ribs), irregular (vertebrae).
- Histological: Compact and cancellous (spongy).
Compact Bone
- Dense, solid lamellae without cavities.
- Located in the shaft of long bones.
- Covers the plates of flat, short, and irregular bones.
Cancellous (Spongy) Bone
- Irregular branching, anastomosing trabeculae.
- Encloses bone marrow cavities.
- Found in the center of flat bones, short bones, irregular bones, and epiphyses of long bones.
Bone Tissue Structure
- Bone Cells:
- Osteogenic cells (osteoprogenitor cells): precursor cells.
- Osteoblasts: bone-forming cells; synthesize osteoid tissue.
- Osteocytes: mature bone cells, maintain bone hardness.
- Osteoclasts: large, multinucleated cells that resorb bone; found in Howship's lacunae.
- Fibers: Collagen type I, forming the organic part of the bone matrix.
- Ground Substance: GAGs & glycoproteins, without water.
- Hydroxyapatite Crystals: Calcium salts, forming the inorganic part of the matrix.
Histology of Compact Bone
- Organizational Layers: Periosteum, external circumferential lamellae, Haversian system (osteon), interstitial lamellae, internal circumferential lamellae, and Endosteum.
- Haversian System: Concentric lamellae surrounding a central canal (Haversian canal). Contains blood vessels, nerves, and connective tissue. Haversian canals communicate between the marrow cavity and periosteum through Volkmann's canals.
Histology of Spongy Bone
- Trabeculae: Irregular branching, anastomosing bony trabeculae.
- Bone Marrow: Cavities enclosed by trabeculae.
- Lamellae: Each trabeculum is formed of irregularly arranged bone lamellae, containing osteocytes. Spongy bone does not contain osteons.
References
- Junqueira's Basic Histology; 13th Edition, 2013, Anthony L. Mescher.
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