11 Questions
What is the major controlling factor in the breakdown of glycogen?
Glycogen phosphorylase
What is the major controlling factor in the production of glycogen?
Glycogen synthase
What physiological conditions require the generation of glucose from non-carbohydrate sources?
Starvation, vigorous exercise
In what cells is it physiologically necessary to generate ATP exclusively from glucose?
Eye cells, nervous system, red blood cells
What is the process by which pyruvate is converted to glucose?
Gluconeogenesis
What are the three irreversible steps in glycolysis?
Steps 10, 3, 1
What vitamin is required as a CO2 carrier in the conversion of pyruvate to phosphoenolpyruvate?
Biotin (vitamin B7)
Which enzyme catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in gluconeogenesis?
Phosphoenolpyruvate carboxykinase (PEPCK)
What is the net cost of ATP, GTP, and NADH in gluconeogenesis?
4 ATP, 2 GTP, and 2 NADH
Can animals produce glucose from single fatty acids?
No
What is the final product of the pentose phosphate pathway's oxidative reactions?
Fructose-6-phosphate and glyceraldehyde-3-phosphate
Test your knowledge of glycogen metabolism, including the role of glycogen phosphorylase and glycogen synthase, as well as the process of gluconeogenesis. Learn about allosteric control, covalent modification, and the regulation of these pathways.
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