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Questions and Answers

What is the primary distinction between qualitative and quantitative analysis?

  • Qualitative analysis requires separation techniques, while quantitative analysis does not.
  • Qualitative analysis is used in industry, while quantitative analysis is used in medicine.
  • Qualitative analysis identifies the amount of substances, while quantitative analysis identifies the substances themselves.
  • Qualitative analysis establishes the chemical identity of substances, while quantitative analysis determines their relative amounts. (correct)

In the context of analytical chemistry, what is an 'analyte'?

  • The instrument used to perform the analysis.
  • A separation technique used in gas chromatography.
  • A component of a sample that is being determined. (correct)
  • A numerical term indicating quantity.

Why is a separation step often incorporated into gas chromatography and mass spectrometry?

  • To selectively remove interfering substances.
  • To reduce the cost of the analysis.
  • As a necessary part of the analytical process for these instruments. (correct)
  • To increase the speed of the analysis.

Which of the following is an example of a direct application of analytical chemistry?

<p>Measuring oxygen and carbon dioxide levels in blood for medical diagnosis. (B)</p> Signup and view all the answers

Why might the APXS and LIBS experiments NOT require chemical separation of elements in rocks?

<p>These methods provide highly selective information. (A)</p> Signup and view all the answers

What role does qualitative analysis play in quantitative analysis?

<p>Qualitative analysis is an essential adjunct to quantitative analysis by determining the identity of the analytes. (C)</p> Signup and view all the answers

Why is it important to measure the quantities of hydrocarbons, nitrogen oxides, and carbon monoxide in automobile exhaust gases?

<p>To assess the effectiveness of emission-control devices. (B)</p> Signup and view all the answers

What is an example of analytical chemistry being applied throughout industry, and all the sciences?

<p>Determining the effectiveness of emission-control devices. (C)</p> Signup and view all the answers

What is the primary role of analytical chemistry as described in the text?

<p>Providing measurement tools across scientific disciplines. (A)</p> Signup and view all the answers

The Mars rover missions utilized analytical chemistry primarily to:

<p>Analyze the chemical makeup of Martian soil and rocks. (B)</p> Signup and view all the answers

Based on data from the Mars rovers, what conclusion was drawn about Mars's past?

<p>Mars was previously a warm, wet planet with surface water. (C)</p> Signup and view all the answers

What analytical instruments did the Spirit rover use to analyze Martian samples?

<p>Alpha particle X-ray spectrometer (APXS) and Mossbauer spectrometer (D)</p> Signup and view all the answers

What significant discoveries did the Spirit rover make using its analytical instruments?

<p>Concentrated deposits of silica and high concentrations of carbonate. (C)</p> Signup and view all the answers

Which instrument package on the Curiosity rover includes a laser-induced breakdown spectrometer (LIBS)?

<p>Chemistry and Camera package (C)</p> Signup and view all the answers

What does 'LIBS' stand for, as featured on the Curiosity rover?

<p>Laser-Induced Breakdown Spectrometer (C)</p> Signup and view all the answers

Why is the continued operation of the Opportunity rover considered 'amazing'?

<p>It greatly exceeded its initial mission timeline and distance traveled. (C)</p> Signup and view all the answers

Which compound has the closest molar mass to ammonium sulfate ((NH4)2SO4)?

<p>Ammonium persulfate ((NH4)2S2O8) (B)</p> Signup and view all the answers

If you have equal masses of potassium chromate (K2CrO4) and potassium dichromate (K2Cr2O7), which one contains more moles of potassium?

<p>Potassium chromate (K2CrO4) (B)</p> Signup and view all the answers

Consider a reaction where lead(II) oxide (PbO) is converted to lead(IV) oxide (PbO2). What is the mass difference expected when 1 mole of lead(II) oxide is completely converted to lead(IV) oxide?

<p>16.0 g (C)</p> Signup and view all the answers

Which of the listed compounds contains the greatest mass percentage of oxygen?

<p>Sulfur trioxide (SO3) (D)</p> Signup and view all the answers

You have 100g of each of the following compounds: KBr, KCl, and KCN. Which sample contains the fewest number of moles of the compound?

<p>KBr (A)</p> Signup and view all the answers

A student needs to prepare a solution with a known concentration of hydrogen peroxide (H2O2). Which of the following steps is most crucial for ensuring the accuracy of the concentration?

<p>Accurately weighing the hydrogen peroxide. (C)</p> Signup and view all the answers

You have equal masses of mercury(I) chloride (Hg2Cl2) and mercury(II) chloride (HgCl2). Which sample contains more moles of chlorine atoms?

<p>Mercury(II) chloride (HgCl2) (D)</p> Signup and view all the answers

Which of the following compounds would result in the highest electrical conductivity when dissolved in water, assuming equal molar concentrations?

<p>(NH4)2SO4 (A)</p> Signup and view all the answers

A researcher discovers a new compound with a molar mass between that of KBrO3 and K2Cr2O7. Which of the following is a plausible molar mass for this compound, based on the compounds listed?

<p>230.0 g/mol (D)</p> Signup and view all the answers

What is the closest whole number estimate for the ratio of the molar mass of $Hg_2Cl_2$ to the molar mass of $P_2O_5$?

<p>3 (B)</p> Signup and view all the answers

Which factor most significantly influences the choice of an analytical method when only a limited number of samples are available?

<p>The need to minimize or avoid extensive preliminary steps. (A)</p> Signup and view all the answers

In quantitative analysis, what is the most critical characteristic of a sample taken from a bulk material?

<p>It must have the same composition as the bulk material. (D)</p> Signup and view all the answers

Why is obtaining a representative sample particularly challenging when dealing with a large and heterogeneous bulk material?

<p>The composition varies significantly throughout the material. (A)</p> Signup and view all the answers

In the context of analyzing a 25-ton railcar of silver ore, what is the primary reason for needing to assay a small, approximately one-gram sample?

<p>To determine the silver content and thus the price, while managing heterogeneity and cost. (B)</p> Signup and view all the answers

Which of the following materials is most likely to be classified as heterogeneous?

<p>A sample of coal. (B)</p> Signup and view all the answers

A pharmaceutical company needs to determine the concentration of an active ingredient in a batch of tablets. They have a limited number of tablets available for testing. Which analytical approach would be most suitable?

<p>A non-destructive method that allows for multiple measurements on the same tablet. (D)</p> Signup and view all the answers

An environmental scientist is tasked with measuring the lead concentration in soil samples from a potentially contaminated site. The soil is known to contain various particle sizes and organic matter. What is the most important consideration when collecting soil samples?

<p>Collecting a composite sample from multiple locations and depths to represent the site accurately. (A)</p> Signup and view all the answers

A mining company is evaluating a new deposit of copper ore. They need to quickly assess the average copper content to determine the deposit's economic viability. Which sampling and analysis strategy would be most appropriate for this initial assessment?

<p>Collecting numerous small samples from various locations within the deposit and performing a rapid, cost-effective assay. (B)</p> Signup and view all the answers

In a blood glucose regulation system using insulin injections, what is the primary controllable quantity that is adjusted to maintain the desired glucose level?

<p>The amount of insulin administered. (D)</p> Signup and view all the answers

What action is typically taken if a patient's measured blood glucose level is below the predetermined threshold in the described feedback system?

<p>The insulin level is maintained, and no additional insulin is administered. (B)</p> Signup and view all the answers

In the context of blood glucose control via insulin, what is the purpose of the 'delay time' mentioned in the passage?

<p>To provide the insulin sufficient time to affect the glucose level. (A)</p> Signup and view all the answers

In the described feedback system, what serves as the 'desired state' that the system aims to achieve?

<p>Achieving a blood glucose level within a specific target range. (A)</p> Signup and view all the answers

If a patient's blood glucose level remains above 100 mg/dL after a suitable delay following an initial insulin adjustment, what is the most likely next step in the described control system?

<p>The insulin level is increased again to further lower the glucose level. (C)</p> Signup and view all the answers

What role does the measurement of blood glucose level play in the closed-loop system described?

<p>It acts as feedback to determine if adjustments to insulin are necessary. (A)</p> Signup and view all the answers

What is the potential consequence of not having a delay between insulin administration and glucose measurement in the described feedback loop?

<p>The effect of insulin on glucose levels might not be accurately assessed. (C)</p> Signup and view all the answers

According to the passage, what condition must be met to discontinue insulin administration in this feedback system?

<p>The patient's blood glucose level has been maintained below a threshold. (A)</p> Signup and view all the answers

Based on the table, which element has the closest atomic mass to that of Iron (Fe)?

<p>Cobalt (Co) (D)</p> Signup and view all the answers

Which of the following elements is represented by a single letter symbol in the periodic table?

<p>Nitrogen (N) (D)</p> Signup and view all the answers

An unknown element is discovered and found to have an atomic mass between that of Europium (Eu) and Gadolinium (Gd). Which of the following atomic masses would be a reasonable estimate for this new element?

<p>154.607 (A)</p> Signup and view all the answers

Which of the following elements has an atomic number greater than 80 but an atomic mass less than 204?

<p>Thallium (Tl) (A)</p> Signup and view all the answers

Based on the table, which of the following comparisons between the atomic masses of Halogens is correct?

<p>Bromine (Br) &gt; Chlorine (Cl) (C)</p> Signup and view all the answers

Which of the following elements has the highest atomic number?

<p>Oganesson (Og) (B)</p> Signup and view all the answers

Consider that a new element, 'Xy', is synthesized with an atomic number of 119. Based on the periodic trends, which element's properties would 'Xy' most closely resemble?

<p>Francium (Fr) (B)</p> Signup and view all the answers

Which of the listed elements would you expect to have similar chemical properties to Sulfur (S)?

<p>Selenium (Se) (C)</p> Signup and view all the answers

An experiment requires an element with an atomic mass as close as possible to 100. Which of the following would be the best choice?

<p>Ruthenium (Ru) (D)</p> Signup and view all the answers

A researcher needs an element with an atomic number between that of Nickel (Ni) and Zinc (Zn) with similar properties to copper. Which element should they consider?

<p>Copper (Cu) (B)</p> Signup and view all the answers

Which of the following elements has an atomic mass that is provided as a mass number in parentheses, indicating it is the most stable isotope rather than a standard atomic mass?

<p>Plutonium (Pu) (B)</p> Signup and view all the answers

If you were to arrange the following elements in order of increasing atomic mass, which would be the correct sequence?

<p>Si &lt; P &lt; S &lt; Cl (A)</p> Signup and view all the answers

Based on the data, which element has approximately 4 times the atomic mass of Magnesium (Mg)?

<p>Strontium (Sr) (B)</p> Signup and view all the answers

Which of the following elements is most likely to be a synthetic (human-made) element?

<p>Neptunium (Np) (D)</p> Signup and view all the answers

Considering the element Lead (Pb), what is the ratio of its atomic number to its approximate atomic mass (rounded to the nearest whole number)?

<p>2:5 (A)</p> Signup and view all the answers

Flashcards

H2O

Water. A molecule consisting of two hydrogen atoms and one oxygen atom.

H2C2O4 ? 2H2O

Oxalic acid dihydrate. A dicarboxylic acid found in many plants.

NH4NO3

Ammonium nitrate. A chemical compound used in agriculture as a high-nitrogen fertilizer.

H5IO6

Periodic acid. Is used as an oxidizing agent.

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(NH4)2SO4

Ammonium sulfate. An inorganic salt with a number of commercial uses.

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HNO3

Nitric acid. A highly corrosive mineral acid.

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H2O2

Hydrogen peroxide. A common oxidizer.

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K2Cr2O7

Potassium dichromate. Common inorganic reagent.

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PbO

Lead(II) oxide. Used in storage batteries.

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SiO2

Silicon dioxide. Also known as silica.

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Analytical Chemistry

A measurement science with powerful tools applicable across science, engineering, and medicine.

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Sojourner Rover

A NASA rover that landed on Mars in 1997 and provided data on the chemical composition of rocks and soil.

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Past Martian Environment

Evidence collected suggested that Mars was once warm and wet.

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Spirit and Opportunity

Two Mars rovers that landed in 2004 with a mission to explore Mars.

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Alpha Particle X-ray Spectrometer (APXS)

An instrument that was used by the Spirit rover to find concentrated deposits of silica and carbonate on Mars.

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Mossbauer Spectrometer

Spirit instrument which found high concentrations of carbonate.

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Curiosity Rover

A Mars rover launched in 2011 and landed in 2012 containing analytical instruments.

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Chemistry and Camera (ChemCam)

An analytical instrument package on the Curiosity rover that includes a laser-induced breakdown spectrometer.

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Atomic Number

Number of protons in an atom's nucleus.

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Atomic Mass

The average mass of an element's atoms, considering the mass and abundance of its isotopes.

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Hydrogen (H) Atomic Mass

Hydrogen's atomic mass.

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Carbon (C) Atomic Mass

Carbon's atomic mass.

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Oxygen (O) Atomic Mass

Oxygen's atomic mass.

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Iron (Fe) Atomic Mass

Iron's atomic mass.

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Gold (Au) Atomic Mass

Gold's atomic mass.

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Lead (Pb) Atomic Mass

Lead's atomic mass.

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Uranium (U) Atomic Mass

Uranium's atomic mass.

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Transuranic Elements

Elements with atomic numbers greater than 92 (Uranium).

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Chlorine (Cl)

Halogen with atomic number 17.

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Neon (Ne)

Inert gas/noble gas with atomic number 10.

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Sodium (Na)

Alkali metal with atomic number 11.

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Magnesium (Mg)

Alkaline earth metal with atomic number 12.

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Copper (Cu)

Transition metal with atomic number 29.

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Qualitative Analysis

Determines the chemical identity of elements and compounds in a sample.

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Quantitative Analysis

Determines the relative amounts of substances (analytes) in a sample numerically.

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Analytes

Components of a sample that are being measured or determined.

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Separation Method

A step in analytical chemistry used to isolate analytes.

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Qualitative Analysis example

Using analytical chemistry to identify substances.

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Quantitative Analysis example

Using analytical chemistry to measure the amounts of substances.

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Separation Step

A process used in analytical instruments to isolate different parts of a sample before analysis.

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Application of Analytical Chemistry

Analytical chemistry is used across industries, medicine, and sciences to determine composition and amounts of substances.

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Assay

The process of determining the amount of a specific component in a sample.

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Representative Sample

A subsample that accurately represents the overall composition of the bulk material.

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Heterogeneous Material

Material with non-uniform composition; its components are visually distinguishable.

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Acquiring the Sample

The physical act of taking a sample.

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Importance of Representative Sampling

Crucial step in quantitative analysis to ensure the analyzed sample mirrors the bulk material's composition.

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Bulk Material

The overall material from which samples are taken; can be very large (e.g., a railcar of ore).

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Single sample analysis

Simplifying preliminary steps to make use of procedures to analyze samples

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Sample Complexity

Sample complexity affects method choice.

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Feedback System

A system where the output (actual state) is compared to the input (desired state), and the difference is used to adjust a controllable quantity to achieve the desired state.

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Desired State

The target or ideal condition that a control system aims to achieve. A pre-defined, reference point.

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Actual State

The current condition or value of a system parameter that a control system is designed to influence or maintain.

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Controllable Quantity

A parameter within a control system that can be directly manipulated to influence the actual state of the system.

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State Measurement

The process of measuring the actual state of a system to compare it against the desired state in a closed-loop control system.

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State Comparison

In a feedback system, it is the analysis of the difference between the desired state and the actual state to make control decisions.

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Threshold

A pre-determined acceptable value or range; if the measured value is outside this, action is taken.

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State Maintenance

Maintaining a value within an acceptable range, indicating that no corrective action is currently required.

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Study Notes

  • Analytical chemistry is a science of measurement.

Analytical Chemistry and Space Exploration

  • Analytical chemistry plays a significant role in NASA's rover explorations on Mars.
  • On July 4, 1997, the Pathfinder spacecraft landed the Sojourner rover on Mars.
  • Analytical instruments on the rover provided info on the chemical composition of Martian rocks and soil.
  • The data suggested that Mars was once warm and wet with water on the surface and vapor in the atmosphere.
  • In January 2004, the Mars rovers Spirit and Opportunity arrived on Mars where Spirit found concentrated deposits of silica and high concentrations of carbonate.
  • The Mars Science Laboratory carrying the rover Curiosity was launched in late 2011.
  • Curiosity landed on Mars on August 6, 2012, carrying analytical instruments.
  • The Chemistry and Camera package includes a laser-induced breakdown spectrometer (LIBS) and a remote microimager.
  • The LIBS instrument is designed to determine the identity and amounts of elements without sample preparation and can detect hydrated minerals.
  • The analysis package contained instruments like a quadrupole mass spectrometer, a gas chromatograph, and a tunable laser spectrometer.
  • The mission included surveying carbon compound sources & searching for organic compounds to determine the composition of the Martian atmosphere and elements.

Qualitative vs. Quantitative

  • Qualitative analysis identifies the elements and compounds in a sample.
  • Quantitative analysis determines the amounts of substances, or analytes, in a sample.

The Role of Analytical Chemistry

  • Analytical chemistry is used in industry, medicine, and all sciences spanning from measuring oxygen and carbon dioxide in blood to diagnosing illnesses, hydrocarbons in auto exhaust gases, calcium in blood serum in humans, and determine nitrogen in foods.
  • Steel analysis during production involves elements like carbon, nickel, and chromium.
  • Analytical measurement are used study nerve-signal conduction and muscle contraction.
  • Chemists use analytical chemistry to unravel chemical reactions with rate studies.
  • Materials scientists study semiconductor devices using analytics from crystalline germanium and silicon.
  • Archaeologists identify volcanic glass origins by measuring minor elements.
  • The interdisciplinary nature of chemical analysis makes it vital in medical, industrial, government, and academic laboratories.

Quantitative Analytical Methods

  • Results from a typical quantitative analysis consist of measurements like the mass or sample volume and measuring a quantity proportional to the analyte amount.
  • Gravimetric methods determine the analyte mass or a chemically related compound mass.
  • Volumetric methods measure the volume of a solution containing enough reagent to completely react with the analyte.
  • Electroanalytical methods is the measurement of electrical properties like potential, current, resistance, and electrical charge.
  • Spectroscopic methods are about the interaction between electromagnetic radiation, analyte atoms, molecules, and radiation emission by analytes.
  • Miscellaneous methods include measuring mass-to-charge ratio of ions, rate of radioactive decay, rate of reaction, sample thermal conductivity, optical activity, and refractive index.

Typical Quantitative Analysis Steps

  • Choosing a Method is the the first thing to do, accuracy levels are considered, and the approach taken reflects the accuracy needed against available resources.
  • Acquiring the Sample is next, and should represent the bulk material from which the analysis comes from.
  • Processing the Sample can take place in different ways or not at all depending on circumstances and a laboratory may be prepared.
  • Most chemical analyses use replicate samples to improve results and reliability.
  • Quantitative measurements are averaged, statistical tests done to confirm reliability.
  • Preparing Solutions involves using a solvent to dissolve the sample (if possible) and if not other chemical analysis is needed
  • Eliminating Interferences removes substances causing measurement errors with analyte isolation being vital.
  • Reactions/properties are standard for compound groups, necessitating interference isolation.
  • Calibrating and Measuring Concentration requires measurement of analyte physical or chemical property (final measurement denoted as X ).
  • The rate of change with analyte concentration, denoted as (ca) is measured during calibration.
  • Calculating Results uses data with computers that use calculations based on experimental data, instrument characteristics, analytical reaction stoichiometry.
  • Evaluating Results by Estimating Reliability means experimenters must give uncertainty measures associated with computed results must be provided.

Heterogeneous vs. Homogeneous Material

  • A material is heterogeneous if its constituent parts are visually distinguishable with something like a microscope, while homogenous materials cannot be broken down any further.

Assays

  • An assay determines the amount of a specific material in a sample, like zinc content in a zinc alloy.

Sampling

  • Sampling is the process of collecting a small mass of a material whose composition represents that of an overall larger whole.
  • Collecting specimens from biological sources are an example of sampling problems because concentrations can vary.
  • Strict processes have been developed for blood gas specimens to ensure integrity.
  • Proper laboratory samples should be representative of the whole.

Feedback Control Systems

  • Analytical chemistry is often an element of a bigger picture, used to control a patient’s health, the amount of mercury in and to learn whether there is life on Mars.
  • Measurement steps for processes like quantitative analysis are used with diabetes to determine blood glucose levels.
  • It is determined through testing samples to compare a desired vs measure level in someones blood.

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