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Questions and Answers
What is the primary distinction between qualitative and quantitative analysis?
What is the primary distinction between qualitative and quantitative analysis?
- Qualitative analysis requires separation techniques, while quantitative analysis does not.
- Qualitative analysis is used in industry, while quantitative analysis is used in medicine.
- Qualitative analysis identifies the amount of substances, while quantitative analysis identifies the substances themselves.
- Qualitative analysis establishes the chemical identity of substances, while quantitative analysis determines their relative amounts. (correct)
In the context of analytical chemistry, what is an 'analyte'?
In the context of analytical chemistry, what is an 'analyte'?
- The instrument used to perform the analysis.
- A separation technique used in gas chromatography.
- A component of a sample that is being determined. (correct)
- A numerical term indicating quantity.
Why is a separation step often incorporated into gas chromatography and mass spectrometry?
Why is a separation step often incorporated into gas chromatography and mass spectrometry?
- To selectively remove interfering substances.
- To reduce the cost of the analysis.
- As a necessary part of the analytical process for these instruments. (correct)
- To increase the speed of the analysis.
Which of the following is an example of a direct application of analytical chemistry?
Which of the following is an example of a direct application of analytical chemistry?
Why might the APXS and LIBS experiments NOT require chemical separation of elements in rocks?
Why might the APXS and LIBS experiments NOT require chemical separation of elements in rocks?
What role does qualitative analysis play in quantitative analysis?
What role does qualitative analysis play in quantitative analysis?
Why is it important to measure the quantities of hydrocarbons, nitrogen oxides, and carbon monoxide in automobile exhaust gases?
Why is it important to measure the quantities of hydrocarbons, nitrogen oxides, and carbon monoxide in automobile exhaust gases?
What is an example of analytical chemistry being applied throughout industry, and all the sciences?
What is an example of analytical chemistry being applied throughout industry, and all the sciences?
What is the primary role of analytical chemistry as described in the text?
What is the primary role of analytical chemistry as described in the text?
The Mars rover missions utilized analytical chemistry primarily to:
The Mars rover missions utilized analytical chemistry primarily to:
Based on data from the Mars rovers, what conclusion was drawn about Mars's past?
Based on data from the Mars rovers, what conclusion was drawn about Mars's past?
What analytical instruments did the Spirit rover use to analyze Martian samples?
What analytical instruments did the Spirit rover use to analyze Martian samples?
What significant discoveries did the Spirit rover make using its analytical instruments?
What significant discoveries did the Spirit rover make using its analytical instruments?
Which instrument package on the Curiosity rover includes a laser-induced breakdown spectrometer (LIBS)?
Which instrument package on the Curiosity rover includes a laser-induced breakdown spectrometer (LIBS)?
What does 'LIBS' stand for, as featured on the Curiosity rover?
What does 'LIBS' stand for, as featured on the Curiosity rover?
Why is the continued operation of the Opportunity rover considered 'amazing'?
Why is the continued operation of the Opportunity rover considered 'amazing'?
Which compound has the closest molar mass to ammonium sulfate ((NH4)2SO4)?
Which compound has the closest molar mass to ammonium sulfate ((NH4)2SO4)?
If you have equal masses of potassium chromate (K2CrO4) and potassium dichromate (K2Cr2O7), which one contains more moles of potassium?
If you have equal masses of potassium chromate (K2CrO4) and potassium dichromate (K2Cr2O7), which one contains more moles of potassium?
Consider a reaction where lead(II) oxide (PbO) is converted to lead(IV) oxide (PbO2). What is the mass difference expected when 1 mole of lead(II) oxide is completely converted to lead(IV) oxide?
Consider a reaction where lead(II) oxide (PbO) is converted to lead(IV) oxide (PbO2). What is the mass difference expected when 1 mole of lead(II) oxide is completely converted to lead(IV) oxide?
Which of the listed compounds contains the greatest mass percentage of oxygen?
Which of the listed compounds contains the greatest mass percentage of oxygen?
You have 100g of each of the following compounds: KBr, KCl, and KCN. Which sample contains the fewest number of moles of the compound?
You have 100g of each of the following compounds: KBr, KCl, and KCN. Which sample contains the fewest number of moles of the compound?
A student needs to prepare a solution with a known concentration of hydrogen peroxide (H2O2). Which of the following steps is most crucial for ensuring the accuracy of the concentration?
A student needs to prepare a solution with a known concentration of hydrogen peroxide (H2O2). Which of the following steps is most crucial for ensuring the accuracy of the concentration?
You have equal masses of mercury(I) chloride (Hg2Cl2) and mercury(II) chloride (HgCl2). Which sample contains more moles of chlorine atoms?
You have equal masses of mercury(I) chloride (Hg2Cl2) and mercury(II) chloride (HgCl2). Which sample contains more moles of chlorine atoms?
Which of the following compounds would result in the highest electrical conductivity when dissolved in water, assuming equal molar concentrations?
Which of the following compounds would result in the highest electrical conductivity when dissolved in water, assuming equal molar concentrations?
A researcher discovers a new compound with a molar mass between that of KBrO3 and K2Cr2O7. Which of the following is a plausible molar mass for this compound, based on the compounds listed?
A researcher discovers a new compound with a molar mass between that of KBrO3 and K2Cr2O7. Which of the following is a plausible molar mass for this compound, based on the compounds listed?
What is the closest whole number estimate for the ratio of the molar mass of $Hg_2Cl_2$ to the molar mass of $P_2O_5$?
What is the closest whole number estimate for the ratio of the molar mass of $Hg_2Cl_2$ to the molar mass of $P_2O_5$?
Which factor most significantly influences the choice of an analytical method when only a limited number of samples are available?
Which factor most significantly influences the choice of an analytical method when only a limited number of samples are available?
In quantitative analysis, what is the most critical characteristic of a sample taken from a bulk material?
In quantitative analysis, what is the most critical characteristic of a sample taken from a bulk material?
Why is obtaining a representative sample particularly challenging when dealing with a large and heterogeneous bulk material?
Why is obtaining a representative sample particularly challenging when dealing with a large and heterogeneous bulk material?
In the context of analyzing a 25-ton railcar of silver ore, what is the primary reason for needing to assay a small, approximately one-gram sample?
In the context of analyzing a 25-ton railcar of silver ore, what is the primary reason for needing to assay a small, approximately one-gram sample?
Which of the following materials is most likely to be classified as heterogeneous?
Which of the following materials is most likely to be classified as heterogeneous?
A pharmaceutical company needs to determine the concentration of an active ingredient in a batch of tablets. They have a limited number of tablets available for testing. Which analytical approach would be most suitable?
A pharmaceutical company needs to determine the concentration of an active ingredient in a batch of tablets. They have a limited number of tablets available for testing. Which analytical approach would be most suitable?
An environmental scientist is tasked with measuring the lead concentration in soil samples from a potentially contaminated site. The soil is known to contain various particle sizes and organic matter. What is the most important consideration when collecting soil samples?
An environmental scientist is tasked with measuring the lead concentration in soil samples from a potentially contaminated site. The soil is known to contain various particle sizes and organic matter. What is the most important consideration when collecting soil samples?
A mining company is evaluating a new deposit of copper ore. They need to quickly assess the average copper content to determine the deposit's economic viability. Which sampling and analysis strategy would be most appropriate for this initial assessment?
A mining company is evaluating a new deposit of copper ore. They need to quickly assess the average copper content to determine the deposit's economic viability. Which sampling and analysis strategy would be most appropriate for this initial assessment?
In a blood glucose regulation system using insulin injections, what is the primary controllable quantity that is adjusted to maintain the desired glucose level?
In a blood glucose regulation system using insulin injections, what is the primary controllable quantity that is adjusted to maintain the desired glucose level?
What action is typically taken if a patient's measured blood glucose level is below the predetermined threshold in the described feedback system?
What action is typically taken if a patient's measured blood glucose level is below the predetermined threshold in the described feedback system?
In the context of blood glucose control via insulin, what is the purpose of the 'delay time' mentioned in the passage?
In the context of blood glucose control via insulin, what is the purpose of the 'delay time' mentioned in the passage?
In the described feedback system, what serves as the 'desired state' that the system aims to achieve?
In the described feedback system, what serves as the 'desired state' that the system aims to achieve?
If a patient's blood glucose level remains above 100 mg/dL after a suitable delay following an initial insulin adjustment, what is the most likely next step in the described control system?
If a patient's blood glucose level remains above 100 mg/dL after a suitable delay following an initial insulin adjustment, what is the most likely next step in the described control system?
What role does the measurement of blood glucose level play in the closed-loop system described?
What role does the measurement of blood glucose level play in the closed-loop system described?
What is the potential consequence of not having a delay between insulin administration and glucose measurement in the described feedback loop?
What is the potential consequence of not having a delay between insulin administration and glucose measurement in the described feedback loop?
According to the passage, what condition must be met to discontinue insulin administration in this feedback system?
According to the passage, what condition must be met to discontinue insulin administration in this feedback system?
Based on the table, which element has the closest atomic mass to that of Iron (Fe)?
Based on the table, which element has the closest atomic mass to that of Iron (Fe)?
Which of the following elements is represented by a single letter symbol in the periodic table?
Which of the following elements is represented by a single letter symbol in the periodic table?
An unknown element is discovered and found to have an atomic mass between that of Europium (Eu) and Gadolinium (Gd). Which of the following atomic masses would be a reasonable estimate for this new element?
An unknown element is discovered and found to have an atomic mass between that of Europium (Eu) and Gadolinium (Gd). Which of the following atomic masses would be a reasonable estimate for this new element?
Which of the following elements has an atomic number greater than 80 but an atomic mass less than 204?
Which of the following elements has an atomic number greater than 80 but an atomic mass less than 204?
Based on the table, which of the following comparisons between the atomic masses of Halogens is correct?
Based on the table, which of the following comparisons between the atomic masses of Halogens is correct?
Which of the following elements has the highest atomic number?
Which of the following elements has the highest atomic number?
Consider that a new element, 'Xy', is synthesized with an atomic number of 119. Based on the periodic trends, which element's properties would 'Xy' most closely resemble?
Consider that a new element, 'Xy', is synthesized with an atomic number of 119. Based on the periodic trends, which element's properties would 'Xy' most closely resemble?
Which of the listed elements would you expect to have similar chemical properties to Sulfur (S)?
Which of the listed elements would you expect to have similar chemical properties to Sulfur (S)?
An experiment requires an element with an atomic mass as close as possible to 100. Which of the following would be the best choice?
An experiment requires an element with an atomic mass as close as possible to 100. Which of the following would be the best choice?
A researcher needs an element with an atomic number between that of Nickel (Ni) and Zinc (Zn) with similar properties to copper. Which element should they consider?
A researcher needs an element with an atomic number between that of Nickel (Ni) and Zinc (Zn) with similar properties to copper. Which element should they consider?
Which of the following elements has an atomic mass that is provided as a mass number in parentheses, indicating it is the most stable isotope rather than a standard atomic mass?
Which of the following elements has an atomic mass that is provided as a mass number in parentheses, indicating it is the most stable isotope rather than a standard atomic mass?
If you were to arrange the following elements in order of increasing atomic mass, which would be the correct sequence?
If you were to arrange the following elements in order of increasing atomic mass, which would be the correct sequence?
Based on the data, which element has approximately 4 times the atomic mass of Magnesium (Mg)?
Based on the data, which element has approximately 4 times the atomic mass of Magnesium (Mg)?
Which of the following elements is most likely to be a synthetic (human-made) element?
Which of the following elements is most likely to be a synthetic (human-made) element?
Considering the element Lead (Pb), what is the ratio of its atomic number to its approximate atomic mass (rounded to the nearest whole number)?
Considering the element Lead (Pb), what is the ratio of its atomic number to its approximate atomic mass (rounded to the nearest whole number)?
Flashcards
H2O
H2O
Water. A molecule consisting of two hydrogen atoms and one oxygen atom.
H2C2O4 ? 2H2O
H2C2O4 ? 2H2O
Oxalic acid dihydrate. A dicarboxylic acid found in many plants.
NH4NO3
NH4NO3
Ammonium nitrate. A chemical compound used in agriculture as a high-nitrogen fertilizer.
H5IO6
H5IO6
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(NH4)2SO4
(NH4)2SO4
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HNO3
HNO3
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H2O2
H2O2
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K2Cr2O7
K2Cr2O7
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PbO
PbO
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SiO2
SiO2
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Analytical Chemistry
Analytical Chemistry
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Sojourner Rover
Sojourner Rover
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Past Martian Environment
Past Martian Environment
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Spirit and Opportunity
Spirit and Opportunity
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Alpha Particle X-ray Spectrometer (APXS)
Alpha Particle X-ray Spectrometer (APXS)
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Mossbauer Spectrometer
Mossbauer Spectrometer
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Curiosity Rover
Curiosity Rover
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Chemistry and Camera (ChemCam)
Chemistry and Camera (ChemCam)
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Atomic Number
Atomic Number
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Atomic Mass
Atomic Mass
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Hydrogen (H) Atomic Mass
Hydrogen (H) Atomic Mass
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Carbon (C) Atomic Mass
Carbon (C) Atomic Mass
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Oxygen (O) Atomic Mass
Oxygen (O) Atomic Mass
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Iron (Fe) Atomic Mass
Iron (Fe) Atomic Mass
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Gold (Au) Atomic Mass
Gold (Au) Atomic Mass
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Lead (Pb) Atomic Mass
Lead (Pb) Atomic Mass
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Uranium (U) Atomic Mass
Uranium (U) Atomic Mass
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Transuranic Elements
Transuranic Elements
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Chlorine (Cl)
Chlorine (Cl)
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Neon (Ne)
Neon (Ne)
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Sodium (Na)
Sodium (Na)
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Magnesium (Mg)
Magnesium (Mg)
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Copper (Cu)
Copper (Cu)
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Qualitative Analysis
Qualitative Analysis
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Quantitative Analysis
Quantitative Analysis
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Analytes
Analytes
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Separation Method
Separation Method
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Qualitative Analysis example
Qualitative Analysis example
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Quantitative Analysis example
Quantitative Analysis example
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Separation Step
Separation Step
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Application of Analytical Chemistry
Application of Analytical Chemistry
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Assay
Assay
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Representative Sample
Representative Sample
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Heterogeneous Material
Heterogeneous Material
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Acquiring the Sample
Acquiring the Sample
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Importance of Representative Sampling
Importance of Representative Sampling
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Bulk Material
Bulk Material
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Single sample analysis
Single sample analysis
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Sample Complexity
Sample Complexity
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Feedback System
Feedback System
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Desired State
Desired State
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Actual State
Actual State
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Controllable Quantity
Controllable Quantity
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State Measurement
State Measurement
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State Comparison
State Comparison
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Threshold
Threshold
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State Maintenance
State Maintenance
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Study Notes
- Analytical chemistry is a science of measurement.
Analytical Chemistry and Space Exploration
- Analytical chemistry plays a significant role in NASA's rover explorations on Mars.
- On July 4, 1997, the Pathfinder spacecraft landed the Sojourner rover on Mars.
- Analytical instruments on the rover provided info on the chemical composition of Martian rocks and soil.
- The data suggested that Mars was once warm and wet with water on the surface and vapor in the atmosphere.
- In January 2004, the Mars rovers Spirit and Opportunity arrived on Mars where Spirit found concentrated deposits of silica and high concentrations of carbonate.
- The Mars Science Laboratory carrying the rover Curiosity was launched in late 2011.
- Curiosity landed on Mars on August 6, 2012, carrying analytical instruments.
- The Chemistry and Camera package includes a laser-induced breakdown spectrometer (LIBS) and a remote microimager.
- The LIBS instrument is designed to determine the identity and amounts of elements without sample preparation and can detect hydrated minerals.
- The analysis package contained instruments like a quadrupole mass spectrometer, a gas chromatograph, and a tunable laser spectrometer.
- The mission included surveying carbon compound sources & searching for organic compounds to determine the composition of the Martian atmosphere and elements.
Qualitative vs. Quantitative
- Qualitative analysis identifies the elements and compounds in a sample.
- Quantitative analysis determines the amounts of substances, or analytes, in a sample.
The Role of Analytical Chemistry
- Analytical chemistry is used in industry, medicine, and all sciences spanning from measuring oxygen and carbon dioxide in blood to diagnosing illnesses, hydrocarbons in auto exhaust gases, calcium in blood serum in humans, and determine nitrogen in foods.
- Steel analysis during production involves elements like carbon, nickel, and chromium.
- Analytical measurement are used study nerve-signal conduction and muscle contraction.
- Chemists use analytical chemistry to unravel chemical reactions with rate studies.
- Materials scientists study semiconductor devices using analytics from crystalline germanium and silicon.
- Archaeologists identify volcanic glass origins by measuring minor elements.
- The interdisciplinary nature of chemical analysis makes it vital in medical, industrial, government, and academic laboratories.
Quantitative Analytical Methods
- Results from a typical quantitative analysis consist of measurements like the mass or sample volume and measuring a quantity proportional to the analyte amount.
- Gravimetric methods determine the analyte mass or a chemically related compound mass.
- Volumetric methods measure the volume of a solution containing enough reagent to completely react with the analyte.
- Electroanalytical methods is the measurement of electrical properties like potential, current, resistance, and electrical charge.
- Spectroscopic methods are about the interaction between electromagnetic radiation, analyte atoms, molecules, and radiation emission by analytes.
- Miscellaneous methods include measuring mass-to-charge ratio of ions, rate of radioactive decay, rate of reaction, sample thermal conductivity, optical activity, and refractive index.
Typical Quantitative Analysis Steps
- Choosing a Method is the the first thing to do, accuracy levels are considered, and the approach taken reflects the accuracy needed against available resources.
- Acquiring the Sample is next, and should represent the bulk material from which the analysis comes from.
- Processing the Sample can take place in different ways or not at all depending on circumstances and a laboratory may be prepared.
- Most chemical analyses use replicate samples to improve results and reliability.
- Quantitative measurements are averaged, statistical tests done to confirm reliability.
- Preparing Solutions involves using a solvent to dissolve the sample (if possible) and if not other chemical analysis is needed
- Eliminating Interferences removes substances causing measurement errors with analyte isolation being vital.
- Reactions/properties are standard for compound groups, necessitating interference isolation.
- Calibrating and Measuring Concentration requires measurement of analyte physical or chemical property (final measurement denoted as X ).
- The rate of change with analyte concentration, denoted as (ca) is measured during calibration.
- Calculating Results uses data with computers that use calculations based on experimental data, instrument characteristics, analytical reaction stoichiometry.
- Evaluating Results by Estimating Reliability means experimenters must give uncertainty measures associated with computed results must be provided.
Heterogeneous vs. Homogeneous Material
- A material is heterogeneous if its constituent parts are visually distinguishable with something like a microscope, while homogenous materials cannot be broken down any further.
Assays
- An assay determines the amount of a specific material in a sample, like zinc content in a zinc alloy.
Sampling
- Sampling is the process of collecting a small mass of a material whose composition represents that of an overall larger whole.
- Collecting specimens from biological sources are an example of sampling problems because concentrations can vary.
- Strict processes have been developed for blood gas specimens to ensure integrity.
- Proper laboratory samples should be representative of the whole.
Feedback Control Systems
- Analytical chemistry is often an element of a bigger picture, used to control a patient’s health, the amount of mercury in and to learn whether there is life on Mars.
- Measurement steps for processes like quantitative analysis are used with diabetes to determine blood glucose levels.
- It is determined through testing samples to compare a desired vs measure level in someones blood.
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