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homeostasis

normal cells have a fairly narrow range of function or steady state.

adaptation

change in cell morphology and function in response to a stimulus. it is reversible.

injury

too much stress exceeds the cell's adaptive capacity.

all of the answer's adaptations except

necrosis

all of this answer's cell injury irreversible except

cloudy swelling

all of this answer's according to cell injury reversible except

hyperplasia

hypertrophy

increase in the size of individual cells in response to stimulus or injury.

hyperplasia

increase in the absolute number of cells

atrophy

decrease size and number of its component cells.

metaplasia

one mature tissue type replaces another mature tissue type.

form of cell injury depends on

all of the above

causes of cell injury

  1. oxygen deprivation, hypoxia, ischemia. The most important cause.
  2. physical and chemical agents.
  3. immunological reactions.
  4. nutritional imbalance.

pathogenesis of cell injury. role of mitochondria

mitochondrial oxidative phosphorylation is disrupted first, decrease ATP.

  1. decreased NA pump, gain of intracellular Na, cell swelling.
  2. altered metabolism, and depletion of glycogen [anaerobic respiration with glycogenolysis].
  3. lactic acid accumulation, decreased PH and increased intracellular osmotic pressure intracellular H2O cell swelling.

cloudy swelling

mild degeneration characterized by cell swelling and granularity of the cytoplasm due to intracellular accumulation of water.

Test your knowledge on cell adaptation and injury with this quiz. Explore concepts of homeostasis, reversible and irreversible cell injury, and adaptations in response to different stimuli.

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