Cellular Adaptation and Injury Quiz
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Questions and Answers

Which of the following best describes hypertrophy?

  • Reversible change in which one adult cell type is replaced by another
  • Increased number of cells in an organ or tissue
  • Decrease in the structural components of the cell
  • Increased size of cells and the organ (correct)
  • Which of the following is an example of metaplasia?

  • Fibrocystic disease of the breast
  • Pressure atrophy (aneurysm, amyloidosis of liver)
  • Excessive growth factor sensitivity
  • Gastric to intestinal epithelium transformation (correct)
  • What represents a reduction in the structural components of the cell?

  • Metaplasia
  • Atrophy (correct)
  • Hyperplasia
  • Hypertrophy
  • What is the main characteristic of atrophy?

    <p>Reduction in the structural components of the cell</p> Signup and view all the answers

    Which condition involves an increase in the number of cells in an organ or tissue?

    <p>Hyperplasia</p> Signup and view all the answers

    Which cellular adaptation involves a reversible change in which one adult cell type is replaced by another adult cell type?

    <p>Metaplasia</p> Signup and view all the answers

    What is the main cause of atrophy known as disuse atrophy?

    <p>Decreased workload</p> Signup and view all the answers

    Which cellular adaptation involves an increase in the number of cells in an organ or tissue?

    <p>Hyperplasia</p> Signup and view all the answers

    What is the main cause of atrophy known as loss of innervations?

    <p>Loss of innervations</p> Signup and view all the answers

    What are the 4 main forms of cellular adaptation mentioned in the text?

    <p>Atrophy, Hyperplasia, Metaplasia, Hypertrophy</p> Signup and view all the answers

    Which of the following is NOT a cause of atrophy?

    <p>Hormonal stimulation</p> Signup and view all the answers

    What histologic changes are associated with atrophy?

    <p>Decreased cell size</p> Signup and view all the answers

    Which of the following is a plausible example of metaplasia?

    <p>Fibrocystic disease of the breast</p> Signup and view all the answers

    What represents an undesirable change if persistent, as it can lead to cancer transformation?

    <p>Metaplasia</p> Signup and view all the answers

    Which cellular adaptation involves an increase in the size of cells and the organ without new cell formation?

    <p>Hypertrophy</p> Signup and view all the answers

    What is the main cause of atrophy known as nutritional atrophy?

    <p>(Cachexia in malignancy and famines)</p> Signup and view all the answers

    What is a plausible example of hyperplasia?

    <p>(breast during pregnancy)</p> Signup and view all the answers

    In what condition does the left ventricle of the heart show hypertrophy?

    <p>(myocardium in hypertension)</p> Signup and view all the answers

    What condition involves bone formation in muscle, such as in myositis ossificans?

    <p>Metaplasia</p> Signup and view all the answers

    "Brown atrophy" is associated with which organ?

    <p>(heart)</p> Signup and view all the answers

    Which of the following best describes atrophy?

    <p>Reduced size of an organ or tissue resulting from a decrease in cell size</p> Signup and view all the answers

    What represents a reduction in the structural components of the cell?

    <p>Atrophy</p> Signup and view all the answers

    What are the 4 main forms of adaptation mentioned in the text?

    <p>Atrophy, hyperplasia, metaplasia, hypertrophy</p> Signup and view all the answers

    Which cellular adaptive responses can occur at any of these steps: Receptor binding signal transduction protein transcription translation export?

    <p>Atrophy</p> Signup and view all the answers

    Which condition involves an increase in the number of cells in an organ or tissue?

    <p>Hyperplasia</p> Signup and view all the answers

    What is the main cause of atrophy known as disuse atrophy?

    <p>Decreased workload</p> Signup and view all the answers

    Which of the following is an example of metaplasia?

    <p>Replacement of cardiac muscle cells with adipose cells</p> Signup and view all the answers

    What is the main characteristic of atrophy?

    <p>Decrease in cell size</p> Signup and view all the answers

    What are the biochemical mechanisms involved in atrophy?

    <p>Decreased protein synthesis and increased protein catabolism (degradation)</p> Signup and view all the answers

    Which cellular adaptation involves a reversible change in which one adult cell type is replaced by another adult cell type?

    <p>Metaplasia</p> Signup and view all the answers

    What represents changes in the cell environment when the cell adaptive capability is exceeded?

    <p>Cell injury</p> Signup and view all the answers

    What represents a new steady state resulting from cellular adaptive responses?

    <p>Adaptation</p> Signup and view all the answers

    Study Notes

    Cellular Adaptations

    • Hypertrophy: an increase in the size of cells and the organ without new cell formation
    • Metaplasia: a reversible change in which one adult cell type is replaced by another adult cell type
    • Atrophy: a reduction in the structural components of the cell
    • Hyperplasia: an increase in the number of cells in an organ or tissue

    Causes of Atrophy

    • Disuse atrophy: caused by lack of use or inactivity
    • Loss of innervations: caused by nerve damage or disruption
    • Nutritional atrophy: caused by malnutrition or starvation

    Examples of Cellular Adaptations

    • Metaplasia: replacement of ciliated epithelial cells with squamous epithelial cells in response to smoking
    • Hyperplasia: increase in the number of cells in the uterus during pregnancy
    • Hypertrophy: increase in the size of muscle cells in response to exercise

    Atrophy

    • Characterized by a reduction in the structural components of the cell
    • Histologic changes associated with atrophy include a decrease in cell size and number
    • Can be caused by disuse, loss of innervations, or nutritional deficiency

    Other Conditions

    • Myositis ossificans: a condition involving bone formation in muscle
    • "Brown atrophy": a condition affecting the heart, characterized by heart muscle cells being replaced by fatty tissue
    • Left ventricular hypertrophy: a condition in which the left ventricle of the heart becomes thicker in response to high blood pressure or other conditions

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    Description

    Test your knowledge of cellular adaptation, injury, and homeostasis with this quiz. Explore the concepts of stress, adaptation, and physiological responses to normal and abnormal conditions.

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