30 Questions
Which of the following is a consideration when developing exercise prescription for cancer patients?
Patient's prior fitness level
What is the normal range for hemoglobin levels?
8-10 g/dL
What is the recommended exercise for a patient with a platelet count of 10,000 mm3?
Light exercise
Which of the following is a potential limitation for exercise in cancer patients?
Bone metastases
What is the recommended exercise for a patient with a white blood cell count of 300 mm3?
No exercises
Which type of breast cancer is confined to the lobules?
Lobular carcinoma in situ (LCIS)
What is the leading cause of morbidity (impairment and dysfunction) due to late complications of breast cancer and its treatment?
Metastatic breast cancer
How many women are estimated to be newly diagnosed with breast cancer in 2019?
268,600
What is the primary purpose of a sentinel lymph node biopsy?
To evaluate the extent of lymph node involvement
Which gene mutation is associated with an increased risk of developing breast and ovarian cancer?
BRCA 1
Which of the following is a common side effect of chemotherapy?
All of the above
What is the purpose of chemotherapy?
To affect cancerous cell proliferation by damaging DNA
Which drug is commonly used as an anti-estrogen therapy?
Tamoxifen
What is the most common type of surgery for breast reconstruction?
Implants
Which muscles play a greater role in stability in the trunk?
Rectus abdominis
Which targeted therapy is given intravenously for about a year to patients with Her2+ breast cancer?
Perjeta
What are potential side effects of Herceptin?
Decreased white blood cell count
What therapy inhibits cell growth and division in breast cancer treatment?
Perjeta
What is the typical dose of radiation therapy delivered per treatment?
3-4 Gy
What are potential impairments following breast cancer treatment?
Radiation fibrosis, scar adhesion, brachial plexopathy
Which of the following is NOT a common treatment approach for head and neck cancer?
XRT and Chemo Medications
Which of the following is a possible treatment side effect of surgery for head and neck cancer?
Swallowing/breathing difficulties
Which of the following is a risk factor for developing radiation fibrosis?
Medical and degenerative disorders
Which of the following is a potential effect of radiation on muscle tissue?
Myopathy can occur
Which of the following is a consideration for physical therapists when treating head and neck cancer patients?
Orthopedic considerations
Which of the following is a key fact about Axillary Web Syndrome?
Cording begins in the axilla and extends to medial ipsilateral arm to antecubital space and base of thumb.
Which of the following is a subjective symptom of Axillary Web Syndrome?
All of the above
Which of the following is a key fact about Breast Cancer Related Lymphedema?
All of the above
Which of the following is a quantitative limb volume assessment technique?
All of the above
Which of the following is a treatment option for Axillary Web Syndrome?
All of the above
Study Notes
Physical Impairments and Management in Breast Cancer Treatment
- Herceptin is a targeted therapy given intravenously for about a year to patients with Her2+ breast cancer.
- Cardiomyopathy, decreased white blood cell count, anemia, and cancer-related fatigue are potential side effects of Herceptin.
- Perjeta is another targeted therapy used in breast cancer treatment that inhibits cell growth and division.
- Radiation therapy destroys cancer cells and inhibits cell growth, typically delivered in doses of 3-4 Gy per treatment and totaling 40-70 Gy.
- Radiation therapy can cause tissue scarring and increase the risk of developing lymphedema and brachial plexopathies.
- Acute, subacute, and chronic stages of radiation therapy can lead to skin impairment, tissue immobility, and adhesions.
- Common upper quarter impairments following breast cancer treatment include chemotherapy-induced peripheral neuropathy, radiation fibrosis, scar adhesion, brachial plexopathy, scapular dyskinesia, and lymphedema.
- Chemotherapy-induced peripheral neuropathy (CIPN) is the second most common acute side effect of cancer intervention and can cause gait and mobility deficits.
- CIPN can result in paresthesia, decreased proprioception, neuropathic pain, muscle weakness, postural instability, and balance problems.
- Management of CIPN includes patient education, assistive devices, exercises, joint mobilizations, gentle compression, and fall prevention recommendations.
- Radiation fibrosis is the pathological development of fibrotic tissue sclerosis due to radiation therapy, potentially leading to loss of elasticity and organ complications.
- Management of radiation fibrosis involves deep tissue work, tissue mobilization, scar mobilization, and prevention of chest wall adhesion.
Test your knowledge of physical impairments and management in breast cancer treatment with this quiz. Learn about the potential side effects of targeted therapies like Herceptin and Perjeta, as well as the impact of radiation therapy on tissue scarring and the development of conditions like lymphedema and brachial plexopathies. Explore common upper quarter impairments and how to manage them, including chemotherapy-induced peripheral neuropathy and radiation fibrosis.
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