Stomach Pathology Part 2 Lecture PDF
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Uploaded by JollyFern
University of KwaZulu-Natal
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Summary
This lecture provides an overview of stomach pathology, focusing on peptic ulcer disease, miscellaneous conditions, and gastric neoplasia. It covers epidemiology, aetiology, clinical features, and complications of various stomach conditions. The lecture also touches on acute and chronic ulcers.
Full Transcript
Pathology of the gastrointestinal tract: The stomach part 2 Department of Anatomical Pathology Date: 02 August 2022 Outline Peptic ulcer disease Miscellaneous conditions Gastric neoplasia Benign Malignant Peptic Ulcer Disease Epidemi...
Pathology of the gastrointestinal tract: The stomach part 2 Department of Anatomical Pathology Date: 02 August 2022 Outline Peptic ulcer disease Miscellaneous conditions Gastric neoplasia Benign Malignant Peptic Ulcer Disease Epidemiology : Lifetime risk for American men is 10% and 4% for American women Usually middle aged/older Peptic Ulcer Disease Major aetiological factors : Hyperacidity H. pylori gastritis Duodenal reflux NSAIDS Smoking Genetic factors Peptic Ulcer Disease Clinical features : Epigastric pain, burning, aching Worse at night or 1-3 hours after a meal Nausea Vomiting Belching Weight loss Peptic Ulcer Disease Ulcers can be : Acute Chronic Acute Gastric Ulceration Can occur in following settings : Part of acute gastritis Complication of a severe stress response e.g. severe burns (Curling ulcer), major trauma, CVA, raised intracranial pressure Extreme hyperacidity e.g. Zollinger-Ellison Syndrome (increased gastrin secretion) Acute Gastric Ulceration Pathology : Usually
