Summary

This document details the definitions and criteria for sepsis and septic shock, as well as their clinical manifestations and references. It covers various aspects of the conditions, from common clinical features to detailed descriptions of the different stages.

Full Transcript

Health Variations 4 NURS3015 Sepsis- Part 3 https://www.youtube.com/watch?v=NsPDjOX8QHA Definitions and Criteria for Sepsis and Septic Shock Harrison's Principles of Internal Medicine. 20th ed. 2018 Clinical Manifestations Michael D, Braghadheeswar ,T, & Khanna, A. "Sepsis and Septi...

Health Variations 4 NURS3015 Sepsis- Part 3 https://www.youtube.com/watch?v=NsPDjOX8QHA Definitions and Criteria for Sepsis and Septic Shock Harrison's Principles of Internal Medicine. 20th ed. 2018 Clinical Manifestations Michael D, Braghadheeswar ,T, & Khanna, A. "Sepsis and Septic Shock – Basics of Diagnosis, Pathophysiology and Clinical Decision Making.” The Medical Clinics of North America 104.4 (2020): 573-85. Clinical Manifestations Cardiovascular Vasodilation (both arteries and veins) Profound hypotension * Myocardial depression Clinical Manifestations Cardiovascular Vasodilation (both arteries and veins) Profound hypotension * Myocardial depression Pulmonary *Acute Respiratory Distress Syndrome * Non-cardiogenic pulmonary edema * Tachypnea Clinical Manifestations Renal *Acute Kidney Injury Clinical Manifestations Renal *Acute Kidney Injury Hematological * anemia, neutropenia, thrombocytopenia, * Disseminated Intravascular Coagulopathy Clinical Manifestations Renal *Acute Kidney Injury Hematological * anemia, neutropenia, thrombocytopenia, * Disseminated Intravascular Coagulopathy Gastrointestinal * hypoxic hepatitis * sepsis-induced cholestasis * hyperammonemia, causing hepatic encephalopathy Clinical Manifestations Renal *Acute Kidney Injury Hematological * anemia, neutropenia, thrombocytopenia, * Disseminated Intravascular Coagulopathy Gastrointestinal * hypoxic hepatitis * sepsis-induced cholestasis * hyperammonemia, causing hepatic encephalopathy Endocrine * Hyperglycemia Clinical Manifestations Renal *Acute Kidney Injury Hematological * anemia, neutropenia, thrombocytopenia, * Disseminated Intravascular Coagulopathy Gastrointestinal * hypoxic hepatitis * sepsis-induced cholestasis * hyperammonemia, causing hepatic encephalopathy Endocrine * Hyperglycemia Neurologic * Sepsis induced encephalopathy- altered mental status, disorientation, agitation, altered sleep/wake cycle, hallucinations References Daniels, R & Nutbeam,T. ABC of Sepsis. Chichester, West Sussex ; Hoboken, NJ: BMJ/ Wiley- Blackwell, 2010. Craft, Judy, Gordon, Christopher J., Author, Huether, Sue E, McCance, Kathryn L, Author, and Rote, Neal S. Understanding Pathophysiology. 3e, Australian and New Zealand ed. 2019. Linton, Adrianne Dill, Matteson, Mary Ann. Medical-surgical Nursing. 7th ed. 2020. Jameson, J. Larry, Fauci, Anthony S., Editor, Kasper, Dennis L., Loscalzo, Joseph, and Harrison, Tinsley Randolph. Harrison's Principles of Internal Medicine. 20th ed. 2018. Ralston, Stuart. Davidson's Principles and Practice of Medicine. 23rd ed. Elsevier Health Sciences, 2018. Font D., Braghadheeswar T., and Khanna A., "Sepsis and Septic Shock – Basics of Diagnosis, Pathophysiology and Clinical Decision Making." The Medical Clinics of North America 104.4 (2020): 573-85.

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