LSM3227 - General Virology Lectures 5-10 PDF

LSM3227- General Virology Topic 6: Living with viruses (1): viral epidemics in Asia and Singapore Wu Jinlu Office@S1A-04-06 [email protected] Tel: 65168476  Viral reproduction numbers: R 0 & Re Herd Immunity, Vaccine Efficacy, and Vaccine Effectiveness...

LSM3227- General Virology Topic 6: Living with viruses (1): viral epidemics in Asia and Singapore Wu Jinlu Office@S1A-04-06 [email protected] Tel: 65168476  Viral reproduction numbers: R 0 & Re Herd Immunity, Vaccine Efficacy, and Vaccine Effectiveness The Past, Present, and Future Infectious Diseases o Small pox o Mpox o Polio o SARS o Measles o HIV o Hepatitis B o Dengue Infectious Diseases In Singapore: Past, Present And Future | SG50 ID 8  R0 & Re R0 is pronounced “R naught.” In epidemiology, the basic reproduction number (sometimes called basic reproductive ratio) is denoted as R0. R0 gives an indication of the epidemic potential of a virus, by representing the average number of new infections generated by an infectious person in a totally naïve population (everyone is susceptible) in the absence of effective control and vaccines. The effective reproductive number (Re) is the average number of secondary cases per infectious case in a population made up of both susceptible and non-susceptible hosts. If R>1, the number of cases will increase, such as at the start of an epidemic. Where R=1, the disease is endemic, and where R