Brugia and Loa Loa PDF

BRUGIA MALAYI & BRUGIA TIMORI are causing lymphatic filariasis is south and south east Asia They produce almost the same pathology and having the same lifecycle as W. bancrofti Vector: Mansonia species [email protected] 11/6/2024 MORPHOLOGY: The microfilariae are 1...

BRUGIA MALAYI & BRUGIA TIMORI are causing lymphatic filariasis is south and south east Asia They produce almost the same pathology and having the same lifecycle as W. bancrofti Vector: Mansonia species [email protected] 11/6/2024 MORPHOLOGY: The microfilariae are 177~230 µm in length. The tail of the microfilariae tapers to a delicate point and exhibits tow terminal nuclei, Have a sheath. [email protected] 11/6/2024 [email protected] 11/6/2024  LOA LOA Tissue nematode [email protected] 11/6/2024  Loa loa, also known as the African eye worm, is a filarial nematode endemic in the rain forests of West and Central Africa. It is transmitted by Chrysops species [email protected] 11/6/2024 MORPHOLOGY The microfilariae of Loa loa are 250 - 300µm. Have a sheath. Tail is curved and full of nuclei Diurnal periodicity ( 12-2 pm) [email protected] 11/6/2024  The adult: as Wuchereria they live in the subcutaneous tissues, may also occur in the subconjunctival tissue Life cycle: Like W. buncrofti [email protected] 11/6/2024 CLINICAL PRESENTATION 1-The adult worm migration through the subcutaneous tissues is not painful and is seldom noticed unless the worm passing over the bridge of the nose or through the conjunctiva of the eye. Involvement of the eye may cause irritation, congestion and pain (rapid process taking approximately 15 – 20 minutes ) [email protected] 11/6/2024 [email protected] 11/6/2024 [email protected] 11/6/2024  2- Calabar swellings: Migratory (fugitive) localized subcutaneous edema Found anywhere on the body but predominate on the extremities. Develop rapidly and may be proceeded by localized pain, pruritus, and urtecaria. [email protected] 11/6/2024 LAB DIAGNOSIS Detection of microfilariaein peripheral blood (during the day) via a thin blood smear, thick smear or preferably via a concentration technique (Knott or nucleopore filter). [email protected] 11/6/2024 [email protected] 11/6/2024