Antiviral Agents (Antiretroviral Drugs) PDF
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Prajwal Waman Ghatol
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Summary
This document provides an overview of antiviral agents used to treat HIV infection, encompassing different types of antiretroviral drugs, their mechanisms of action, and their possible interactions with other medications. The study details specific antiviral drugs and their adverse effects.
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Antiviral Agents (Antiretroviral Drugs) -Prajwal Waman Ghatol These are drugs active against human immuno-deficiency virus (HIV) which is a retrovirus. They are useful in prolonging and improving the qu...
Antiviral Agents (Antiretroviral Drugs) -Prajwal Waman Ghatol These are drugs active against human immuno-deficiency virus (HIV) which is a retrovirus. They are useful in prolonging and improving the quality of life and 01. postponing complications of acquired Introduction immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC), but do not cure the infection. The clinical efficacy of anti-retrovirus drugs is monitored primarily by plasma HIV-RNA assays and CD4 lymphocyte count carried out at regular intervals. Prajwal Ghatol HIV is a single stranded RNA retrovirus which uniquely carries out reverse transcription of pro- viral DNA from viral RNA (normally RNA is transcripted from DNA) with the help of a viral Introduction 02. RNA-dependent DNA polymerase (reverse transcriptase). The primary cell type attacked by HIV is the CD4+ helper T-lymphocytic, but later macrophages and some other cell types may also be infected. When population of CD4 cells declines markedly (