Cairo University Immunology Mid-term Exam 2024 PDF

CAIRO UNIVERSITY FACULTY OF SCIENCE, ZOOLOGY DEPARTMENT Mid-term Exam in Immunology (Z 202) For 2nd level Students April, 2024 Time...

CAIRO UNIVERSITY FACULTY OF SCIENCE, ZOOLOGY DEPARTMENT Mid-term Exam in Immunology (Z 202) For 2nd level Students April, 2024 Time allowed: 30 min. Code No.: Name: Choose the correct answer: 1. ………………provide sites for the interaction of lymphocytes with the antigens. a. Primary lymphoid organs b. Secondary lymphoid organs* c. Both a&b d. None of the above 2. ………………identify and destroy parasites, cancer cells and assists basophils with your allergic response. a. Neutrophils b. Eosinophils* c. Lymphocytes d. Monocytes 3. The immune system that generates immunological memory exposure to an infectious agent produces an immune response that can persist and protect the host in a subsequent exposure is called_______. a. innate immune system b. adaptive immune system* c. all the above d. none of the above 4. Microbicidal action of secreted molecules is to_______. a. inhibit or kill microbes and damage the microbial membranes b. facilitate the ingestion and destruction of microbes by phagocytes c. act as chemo attractants for cells of the innate immune system d. all the above* 5. The respiratory tract is lined with _______. a. Sticky mucus secreted by goblet cells b. Epithelial cells are covered with cilia c. Thick keratinized layer d. Both a&b* 6. People who are immunocompromised _______. a. their immune systems do not function effectively b. commensal microbes can cause disease to them c. commensal microbes are not pathogenic to them d. both a&b* 7. The four PRR families usually differ in_______. a. their ligand recognition b. signal transduction c. sub-cellular localization d. all the above* 8. Pattern recognition receptors (PRRs) are mainly expressed by _______. a. antigen presenting cells b. dendritic cells & macrophages c. other immune and non-immune cells. d. all the above* 9. Primary Lymphoid Organs provide appropriate microenvironments for_______. a. the development and maturation of lymphocytes * b. proliferation and differentiation of lymphocytes. c. both a&b d. none of the above 10. The skin is the most important barrier to infection due to_______. a. the moist surface b. the epithelial cells are covered with cilia c. the dry and acidic surface* d. continually produce sticky mucus 11. Which of the following is a characteristic or function of an effector T cell? a. Macrophage activation b. B cell activation c. Cytotoxicity d. All the above * 12. To elicit the best antibodies to mouse MHC I, you should inject it into_______. a. a goat* b. a mouse of the same genetic background (strain) c. a mouse of a different strain d. a rat 13. B and T lymphocytes differ from each other in which one of the following characteristics? a. The morphology of the cell. b. The type of antigen that stimulates the response.* c. The ability to produce a memory response. d. B cells are stimulated by antigen whereas T cells are not. 14. Class I MHC molecules are expressed on_______. a. lymphocytes b. somatic cells c. fibroblasts d. all the above* 15. Which of the following statements does not apply to IgG? a. Appears early in the immune response.* b. Neutralizes bacterial toxins. c. Can fix complement. d. Crosses the human placenta. 16. Which of the following statements about a secondary (memory) antibody response is FALSE? a. The secondary response comes from memory B cells. b. The secondary response is faster. c. The secondary response is primarily IgM.* d. The secondary response produces more immunoglobulins than the primary response. 17. Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces? a. IgE. b. gamma interferon. c. class I MHC antigens. d. class II MHC antigens.* 18. Secondary immune organs are the principal sites where ____. a. B cells rearrange immunoglobulin genes b. T cells rearrange T-cell receptor genes c. most antibody secretion by plasma cells takes place d. B and T cells initially encounter foreign antigen* 19. Passive and active immunity differ in that ONLY the passive _______. a. results from supplying the patient with antibodies from another organism* b. risks making the patient sick from a reaction to the therapy c. uses immune elements that are part of the adaptive response d. defends the patient with a primarily cellular response 20. Viruses can stimulate cell mediated immunity because_______. a. they are extracellular b. peptides from the virus bind to class I MHC molecules * c. viral peptides are presented with Abs on B cells d. all the above Best Wishes & Good Luck Prof. Dr. Noha A. Mahana Dr. Asmaa Abd Elkader