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UltraCrispOnyx7877

Uploaded by UltraCrispOnyx7877

University of Alberta

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biological basis of behavior neurobiology nervous system neuroscience

Summary

This document provides an overview of the biological basis of behavior, focusing on the nervous system and its components. It covers the structure and function of neurons, neural communication, and different types of neurotransmitters, and it also includes explanations of neural plasticity and how the nervous system is structured in the brain.

Full Transcript

CHAPTER 3: BIOLOGICAL BASIS OF BEHAVIOR Nervous system divided to 2 PARTS CENTRAL NERVOUS SYSTEM (CNS): Contains brain, spinal cord, optic nerve, retina PERIPHERAL NERVOUS SYSTEM(PNS): sympathetic/parasympathetic, EVERYTHING ELSE BRAIN Contains 2 NERVE CELLS: - NEURONS: Unit of nervous system,...

CHAPTER 3: BIOLOGICAL BASIS OF BEHAVIOR Nervous system divided to 2 PARTS CENTRAL NERVOUS SYSTEM (CNS): Contains brain, spinal cord, optic nerve, retina PERIPHERAL NERVOUS SYSTEM(PNS): sympathetic/parasympathetic, EVERYTHING ELSE BRAIN Contains 2 NERVE CELLS: - NEURONS: Unit of nervous system, requires glucose for function - GLIAL CELLS: Provides structural/nutritional help to brain NEURON composed of DENDRITES, CELL BODY, AXON, AXON TERMINAL CELL BODY(SOMA): Integrates electrical signals DENDRITE: Extension of cell body, collects information from other neurons AXON: Conducts information to other neurons, could be myelinated or unmyelinated AXON TERMINALS: Contact dendrites of other neurons AXON TERMINAL AND COMMUNICATION BETWEEN NEURONS - Inside axon terminal are synaptic vesicles(neurotransmitters) - When action potential travels down axon, synaptic vesicles bind to wall of terminal and release neurotransmitters into synaptic cleft between the 2 neurons - They then bind to receptors on the dendrites of other neuron NEURAL IMPULSE (ACTION POTENTIAL) Within neurons are POTASSIUM IONS Outside of neurons are SODIUM IONS - Potassium inside are positively charged but proteins within make the overall charge INSIDE the neuron NEGATIVE - OUTSIDE of neuron is POSITIVELY CHARGED This negative/positive charged create a POTENTIAL for an electrical charge to occur, so neuron membrane separates them until needed PRESYNAPTIC NEURON: neuron releasing neurotransmitters into synaptic cleft POSTSYNAPTIC NEURON: neuron that receives the neurotransmitters NEUROTRANSMITTERS: 1) ACETYLCHOLINE(ACh) - Released by motor neurons for skeletal movement (found in poisons also) - Contributes to regulation of attention, arousal, memory, sleep - Nicotine stimulates, alzheimers associated with low levels of ACh 2) MOANIMINES (DOPAMINE)(DA) - Contributes to control of voluntary movement - Cocaine/Amphetamines elevate dopamine activity - Schizophrenia implicated as OVERACTIVITY of dopamine - Reward pathway (SEROTONIN)(5-HT) - Involved in regulation of sleep/wakefulness, eating, aggression - Prozac and other antidepressants affect serotonin circuits (increase serotonin) (NOREPINEPHRINE)(NE) - Brain arousal and functions like mood, hunger, sleep, sexual behavior - Functions as hormone and neurotransmitter - Adrenaline basically 3) AMINO ACIDS (GABA) - Brain's main INHIBITORY transmitter - Contributes regulation of anxiety, sleep, arousal - Anti anxiety drugs work at Gaba synapses (GLUTAMATE) - Main EXCITATORY neurotransmitter in nervous system - Relay of sensory information and learning (too much = schizophrenia) 4) ANANDAMIDE (unconventional neurotransmitter) - Binds to same receptors as THC(Cannabis) - Plays role in eating, memory, motivation, sleep (Cannabis symptoms) 5) NEUROPEPTIDES (ENDORPHINS) - Regulated by PNS, synthesized in pituitary. - Function as HORMONE and neurotransmitter - Naturally occurring painkiller - Inhibit communication of pain signals to spinal cord NERVOUS SYSTEM (neurotransmitters) is FAST COMMUNICATION SYSTEM, ENDOCRINE SYSTEM (hormones) is SLOWER COMMUNICATION (released into blood) NEURAL PLASTICITY: Nervous system has the ability to adapt/change NEURAL PLASTICITY IN EARLY DEVELOPMENT: 1) Growth of dendrites/axons 2) Synaptogenesis (formation of new synapse)(neurons exchanged through synapse) 3) Pruning (removal of extra synapses to increase efficiency)(occurs until 10, 70% of neurons destroyed 4) Myelination (growth of myelin sheaths) NEURAL PLASTICITY AND LEARNING: - Could occur through STRUCTURAL CHANGES Axonal growth Dendrite branching/growth Enriched environments lead to axonal growth/dendrite branching more POTENTIATION: When a specific presynaptic neuron has a greater say in the postsynaptic neurons ability to fire (EX: unfair democracy, where ONE person has more power)(“neurons that fire together wire together”) NEURAL PLASTICITY FOLLOWING INJURY - Brain can take over functions previously performed by other parts - Searching for treatments to promote healing/prevent damage in brain (stem cells) - Neurogenesis (creation of new neurons in adult brain)(very few) THE MENINGES: 3 LAYERED PROTECTIVE MEMBRANE that covers brain & spinal cord - Dura Mater - Arachnoid Mater - Pia Mater FURTHER PROTECTION: CEREBRAL VENTRICLES containing cerebrospinal fluid FRONTAL LOBE: Has the Central Sulcus, divides frontal & parietal lobe - Primary Motor Cortex: part of frontal lobe responsible for body movement - Prefrontal Cortex: responsible for thinking, planning, language PARIETAL LOBE: Processes touch information, integrates vision and touch TEMPORAL LOBE: Processes auditory information, language, autobiography memory - Wernicke's Area: part of temporal lobe involved in understanding speech OCCIPITAL LOBE: Back part of cerebral cortex, specialized for vision SUBCORTICAL STRUCTURES (beneath the cerebral cortex) THE BASAL GANGLIA - Group of nuclei (clusters of neurons) located beneath the cerebral cortex - Involved in goal motivated motor control - Contains dopamine neurons and associated with reward and motivation LIMBIC SYSTEM: includes THALAMUS, HYPOTHALAMUS, HIPPOCAMPUS, AMYGDALA - THALAMUS: Gateway from sense organs to primary sensory cortex All sensory information, except smell, relayed through thalamus - HYPOTHALAMUS: Bridge between CNS and Endocrine system Regulates the pituitary gland Responsible for: FLEEING, FIGHTING, FEEDING, FORNICATION - HIPPOCAMPUS: Regulates spatial memory, humans have 2 hippocampi May be necessary for formation of new memories - AMYGDALA: Plays key role in fear, excitement, and arousal

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