Cholinergic Agonists NUR 210/BSL 101 Unit 4 PDF

Cholinergic Agonists NUR 210/BSL 101 Unit 4  Stimulate the parasympathetic nervous system Cholinergic Mimic the neurotransmitter acetylcholine Agonists Muscarinic receptors Affect smooth muscles, slow heart...

Cholinergic Agonists NUR 210/BSL 101 Unit 4  Stimulate the parasympathetic nervous system Cholinergic Mimic the neurotransmitter acetylcholine Agonists Muscarinic receptors Affect smooth muscles, slow heart rate Nicotinic receptors Affect skeletal muscles  Eye Constricts pupil Lungs Effects of Constricts bronchioles, increases Cholinergic secretions Heart and Blood vessels Agonists Decreased heart rate and dilated blood vessels Gastrointestinal Increases peristalsis and secretions Bladder Constricts the bladder Salivary and sweat glands Increases secretions Cholinergic Action Stimulates the cholinergic receptors Agonist – ◦ This stimulation causes contraction of Bethanechol the bladder Chloride Other actions Increases GI secretions and peristalsis Increases bronchial secretions and bronchoconstriction Constricts pupils Uses Treats urinary retention Cholinergic Agonist – Side Effects/Adverse reactions Bethanechol Blurred vision Chloride Increased secretions – lungs, GI tract, sweat Orthostatic hypotension Bronchoconstriction Hypotension, Tachycardia Cholinergic Agonist – Bethanechol Assessment Chloride Vital signs Assess urine output Medication/medical history  Interventions Cholinergic Monitor vital signs – watch for a decrease in BP and pulse Agonist – Monitor lung sounds Bethanechol Monitor GI/GU status Chloride Monitor and record intake & output Give 1 hour before or two hours after meals Monitor for overdose ◦ Signs and symptoms include muscular weakness & increased salivation ◦ Antagonist - Atropine  Teach client to Cholinergic Monitor their blood pressure and heart rate Agonist – and parameters to report Bethanechol Rise slowly from a lying position to prevent Chloride orthostatic hypotension Take on an empty stomach one hour before or two hours after meals Report increased muscle weakness or salivation Evaluations Client able to empty bladder  Action Cholinergic Constricts the pupil which opens the Agonist - canal of Schlemm to promote drainage Pilocarpine of the aqueous humor 1 Uses Decrease pressure in the eye in diseases such as glaucoma Given as eye drops – review for proper eye drop administration