Adrenergic Blockers - NUR 210/BSL 101 - Unit 4 PDF

Adrenergic Blockers NUR 210/BSL 101 Unit 4  Action Block the alpha1 receptor sites – will come up later in quarter ◦ Results in vasodilation, decreased Adrenergic...

Adrenergic Blockers NUR 210/BSL 101 Unit 4  Action Block the alpha1 receptor sites – will come up later in quarter ◦ Results in vasodilation, decreased Adrenergic blood pressure, pupil constriction, reduces contraction of the smooth Blockers – Alpha muscle in the bladder neck and prostate blockers Use ◦ Antihypertensive ◦ Benign prostatic hypertrophy (BPH) ◦ Reynaud’s disease All drugs in this class end in ‘sin’- these drugs works mainly on the vessels  Action Beta 1 Blocker Adrenergic ◦ Blocks beta adrenergic receptor sites Blockers – Beta ◦ Decreases movement of epinephrine ◦ Suppresses renin-angiotensin-aldosterone Blocker system Beta2 Bronchoconstriction Contracts uterus Inhibits glycogenolysis ◦ Leads to hypoglycemia  Uses ◦ Antihypertensive ◦ Angina Adrenergic ◦ Heart failure Blockers – Beta ◦ Dysrhythmias Blocker Drugs in this class end in ‘olol’ – these drugs work on the heart and vessels Selective versus non-selective Drug starts with A-M more selective to beta 1 Drug starts with N-Z non-selective and blocks beta 1 and beta 2  Side effects/Adverse reactions Beta Adrenergic Opposite of adrenergic drugs Blockers – Beta ◦ Drowsy, dizzy, headaches Blocker ‘olol’s ◦ Depression, decreased libido ◦ Orthostatic hypotension ◦ Bradycardia, hypotension ◦ Masking of hypoglycemia  Contraindications Heart block, bradycardia Asthma (unless selective beta 1 – these begin with letters A-M as a rule – atenolol. These are Beta Adrenergic safer than non-selective) Pregnancy Blockers – Beta ◦ Caution Blocker ‘olol’s ▪ Renal dysfunction ▪ Diabetes Interactions Decreased effect with NSAIDS Increased effect with other antihypertensives and antidysrhythmics Increased risk of hypoglycemia with insulin and sulfonylureas and masks the symptoms Beta Adrenergic Assessment Blockers – Beta Blocker ‘olol’s Baseline vital signs EKG Current medications Health history  Interventions Beta Adrenergic Monitor vital signs – report marked Blockers – Beta changes in blood pressure or pulse below 60 Blocker ‘olol’s Report bothersome side effects that don’t improve such as dizziness, lightheadedness, stuffy nose, or depression Provide for safety – orthostatic hypotension  Teaching Take medication at the same time every day Beta Adrenergic Therapeutic effect can take several Blockers – Beta weeks Blocker ‘olol’s Client to monitor their blood pressure and pulse and record Get up slowly to help prevent orthostatic hypotension To side effects/adverse reactions to report Do not drive until response to drug is known Beta Adrenergic Blockers – Beta Evaluation Blocker ‘olol’s Blood pressure decrease Pulse decrease Side effects managed