Organic Chemistry Training Tests PDF 2024-2025

«С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry departm...

«С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из ORGANIC CHEMISTRY TRAINING TESTS discipline _Chemistry_ course of study_1_ specialty_Medicine, Pediatrics_ language of instruction_English_ department/module_Chemistry_ academic year _ - Theoretical foundations of the structure and reactivity of organic compounds 1. What name corresponds to a hydrocarbon radical? *isobutyl *isopropyl *sec-butyl *tert-butyl *propyl 2. What name corresponds to a hydrocarbon radical С Н -СН - ? *propyl *isopropyl *phenyl *vinyl *benzyl. Which class of organic compounds does this compound belong to? *ester *ether *aldehyde *acid *ketone. Which functional group of the ethanolamine molecule is reflected in the title according to the IUPAC rules as a prefics? *hydroxy-group *carboxy-group *amino -group *nitro -group *oxo -group  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из. Which functional groups of the serine molecule ( ) is reflected in the title according to the IUPAC rules as a suffix? *hydroxy-group *carboxy-group *amino -group *nitro -group *oxo -group. Which alkane is the parent structure in the given compound? *hexane *heptane *pentane *butane *octane 7. How many primary carbon atoms are there in the compound? * * * * * 8. How many secondary carbon atoms are there in the compound? * * * * *. Are the compounds…  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из and *identical (same) *chain isomers *different compounds that are not isomers *dimensional (geometric) isomers *functional group isomers. Are the compounds… and *identical (same) *chain isomers *different compounds that are not isomers *dimensional (geometric) isomers *functional group isomers. Which pair of compounds are interclass isomers? *ketones and ethers *ethers and alcohols *alcohols and acids *esters and alcohols *aldehydes and acids. What is the name of the following compound according to the IUPAC nomenclature ( ) ( ) ? *2,3-dimethylpentane * ,2 dimethylpentane * ,3-dimethylpentane *2,2,3-trimethylbutane *2,3,3-trimethylpentane. What is the name of the following compound according to the IUPAC nomenclature? * -ethyl- -methylisohexane * ,5,6-trimethylheptane *2-ethyl- , -dimethylhexane * , , -trimethylheptane *2,3-dimethyl-5-ethylhexane  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из 14. What is the type of the folowing reaction CH CH NH CH + CH I→? *acylation *alkylation *decarboxylation *dehydration *hydrolysis 15. What is the type of the folowing reaction CH СН NH + (CH СО) О →? *decarboxylation *dehydrogenation *dehydration *acylation *hydrolysis. Polyatomic alcohol is *glycerol *methanol *ethanol *toluene *phenol 17. What alcohol is represented by this formula? *primary monoatomic alcohol *secondary monoatomic alcohol *tertiary monoatomic alcohol *secondary diatomic alcohol *primary diatomic alcohol. What is the functional group of aldehydes and ketones? *-ОН *-S-S- *-SH *-C(O)- *-COOH 19. Which of the Bronsted acids is the strongest (according to Bronsted-Lowry)? *phenol (pKa=10) *ethanethiol (pKa=10.5) *glycerol (pKa=14) *ethanol (pKa=16)  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *water (pKa=15.7 20. What is the name of the following compound according to the IUPAC nomenclature? *butanal *butanone *pentanal *propanone * -pentanol. What is the name of the following compound according to the IUPAC nomenclature? * -butanol * -methyl-2-propanol * -propanol * -butanol * , -dimethylethanol Homofunctional derivatives of hydrocarbons. Which of the following statements is TRUE in relation to the compounds – ( ) С Н ОН; ( ) С Н ОН; ( ) С Н СООН? *compounds , and are Arrhenius acids *compounds 2 and 3 are capable of interacting with alkali *compounds 1 and 3 are poorly soluble in water *compound 1 is a stronger acid than compound 2 *acidity decreases in the series of compounds 3>1>2 2. What compounds are Bronsted bases? *neutral molecules or ions capable of accepting a proton *neutral molecules or ions capable of donating a proton *electron pair acceptors *electron pair donors *particles with an unpaired electron 3. Compound which is capable of reacting with an aqueous alkaline solution is * * *  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из * * 4. What reagent is used to distinguish polyatomic alcohols? *bromine water *KMnO solution *Cu(OH) in the cold *Cu(OH) when heated *FeCl solution 5. What reagent is used to distingwish primary amines? *HNO *HNO *CuOH *FeCl *Cu(OH) [ ] 6. Which compound is formed by the reaction of ( ) → *propane *propene *propyne *propanone *propanal. Reduction of which compound gives primary alcohol as a product? *acetone *isopropylalcohol *benzaldehyde *methylpropyl ketone *acetophenone. In which reaction is the salt formed? [ ] *CH SH → [ ] *C H S-S C H → *С Н NH + HCl → *CH ОН + CH СООН → *CH CООН + C H NН →. In which reaction is an ether formed? [ ] *CH SH → [ ] *C H S-S C H →  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *С Н NH + HCl → *CH ОН + CH СООН → *CH ОН + CH ОН →. Choose esterification reaction *CH ОН + Н PO → *CH СН ОН + СН ОН→ *CH ОН + CH ОН → *НО СН СН ОН + Сu(OH) → *С Н NH + HCl→. Which compound is oxidized in reaction with Fehling's reagent when heated and gives a red precipitate of copper (I) oxide? *acetone *acetic acid *dimethyl ether *ethyl alcohol *formaldehyde 12. What is the product of the folowing reaction CH CH=O + C H OH → ? *ketone *acetal *aldehyde *semi-acetal *ether 3. Which pair of interacting compounds leads to the formation of aldol? * → * → * → * → * →. What reagent can detect aldehydes? *bromine water *nitrous acid *copper (II) hydroxide when heated *iron (III) chloride *copper (II) hydroxide when cold. Which compounds form hemiacetal as a product by interaction in acidic medium?  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из * propanol and ethanol in equimolar ratio * two moles of propanol and one mole of ethanal * one mole of propanol and one mole of ethanal * propanoic acid and ethanol in an equimolar ratio * two moles of propanal 16. What is the formula of oxalic acid? * * * ( ) * ( ) * ( ) 17. What are the salts of malonic acid called? *butyrates *malonates *oxalates *succinates *malates 18. Which of the following acids is the weakest? *acetic acid *formic acid *chloroacetic acid *trichloroacetic acid *dichloroacetic acid. Which of the following acids decarboxylates most easily when heated to form monocarboxylic acids? *succinic (butanedioic acid) *glutaric (pentanedioic acid) *acetic (ethanoic acid) *oxalic (ethanedioic acid) *butyric acid (butanoic acid). What is the product of the folowing reaction → ? *ester *ether *amide *anhydride *hydroxyacid. Which acid is formed by hydrolysis of ( ) ? *acetic acid  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *butyric acid *caproic acid *propionic acid *valeric acid. Which acid is formed by hydrolysis of ? *acetic acid *butyric acid *propionic acid *isobutyric acid *valeric acid 23. What compound forms an anhydride when reacted with acetic acid? *ethyl alcohol *acetic acid *acetaldehyde *acetone *benzene. Choose products of propylacetate hydrolysis *СН -СН -СН=О + С Н ОН *СН СООН + С Н ОН *НООС-СООН + С Н ОН *СН -СН -СООН + С Н ОН *СН -СН -СН=О + С Н ОН. What product is formed by the following reaction С Н СООН + С Н ОН → ? *ethyl acetate *ethyl formate *propyl acetate *ethyl propionate *propyl butyrate 26. Which product is missed in the deamination reaction? NH2-CH2-СН + HNO2 → …… + N2 + H2O? *НООС-СН -СН *CH -СН - СН *НО-CH -СН -ОН *HO-CH -СН *CH -СООН  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из Heterofunctional derivatives of hydrocarbons. Heterofunctional compound is… *НО-СН -СН -ОН *НО-СН -СН -NH *H N-СН -СН -NH *НОOC-СН -COOH *СН -СН -СОOH. What is the common name of the compound ( ) ? *lactic acid (2-hydroxypropanoic acid) *oxalic acid (ethanedioic acid) *glycolic acid (2-hydroxyethanoic acid) *tartaric acid (dihydroxybutanedioic acid) *pyruvic acid (2-oxopropanoic acid) 3. What is the common name of the compound? *lactic acid (α-hydroxypropionic acid) *glycolic acid (α-hydroxyacetic acid) *pyruvic acid (α-ketopropionic acid) *acetoacetic acid (β-ketobutyric acid) *oxaloacetic acid (α-ketosuccinic acid) 4. How many asymmetric (chiral) carbon atoms are present in the following compound СН СН(OH) CН(NH ) СООН? * * * * * 5. What product is formed when the next compound is reduced? *hydroxy acid *oxo acid *keto acid *amino acid *monocarboxylic acid 6. What functional groups does hydroxy carboxylic acid contain?  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *hydroxyl and carboxyl groups *carbonyl and carboxyl groups *hydroxyl and carbonyl groups *amide and carboxyl groups *thiol and carbonyl group 7. What is the name of the following type of tautomerism in organic chemistry? *lactim-lactam tautomerism *cyclo-oxo tautomerism *ring-chain tautomerism *keto-enol tautomerism *amino-imine tautomerism. What is product of the reaction: Oxaloacetic acid (2-oxobutanedioic acid) decarboxylation? * 3-oxopropanoic acid * 2-oxopropanoic acid * 3-hydroxypropanoic acid * 2-hydroxypropanoic acid * 3-oxobutanoic acid. What is the acylation product of the following compound ? *ethanolamine *choline *serine *ethanol *colamine. What is the type of reaction of malic acid preparation according to the cheme: Fumaric acid → Malic acid → Oxaloacetic acid *hydration *oxidation *alkylation *acylation *decarboxylation. The transformation scheme is given: What will be the name of substance X? *ethanol  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *choline *acetylcholine *serine *ethanolamine. The reaction scheme is given: β-hydroxybutyric acid → β-ketobutyric acid → acetone. What type of reaction is used to obtain β-ketobutyric acid from β-hydroxybutyric acid according to this scheme? *deamination *dehydrogenation *alkylation *acylation *decarboxylation. What is the product of reaction of glyoxalic acid (oxoethanoic acid) with Fehling’s reagent? *tartaric acid *pyruvic acid *oxalic acid *lactic acid *glycolic acid 14. What product is formed during the esterification of salicylic acid → ? *acetylsalicylic acid *salicylic acid *sodium salicylate *phenyl salicylate *methyl salicylate Amino acids. Biologically important properties of α-amino acids. Peptides. An essential α-amino acid is *serine *glycine *proline *alanine *isoleucine. Which formula is glycine (aminoacetic acid)? * *  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из * ( ) * * ( ). Hydrophilic ionogenic is a α-amino acid… *lysine *threonine *cysteine *leucine *methionine. A hydrophilic interaction takes place between the radicals of the following amino acids *lysine and aspartic acid *arginine and serine *leucine and lysine *alanine and leucine *serine and glutamine. What is the name of the following aminoacid ? *glycine (aminoacetic acid) *alanine (α-aminopropionic acid) *valine (α-aminoisovaleric acid) *leucine (α-aminoisocaproic acid) *isoleucine (α-amino-β-methylvaleric acid). 2-amino-4-methylpentanoic acid is the name of α-amino acid *isoleucine *glutamine *cysteine *leucine *methionine. Which natural α-amino acid contains an amide group? *threonine *lysine *asparagine *arginine *cysteine 8. How many peptide bonds are in a tetrapeptide? *  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из * * * *. The isoelectric point is in the range of pH values < 7 for the dipeptide *glycyl glycine *glycyl lysine *glutamyl lysine *alanyl glycine *asparagyl glutamine 10. Which of the following forms of alanine (pI=6.0) will predominate at pH=12? * * * * *. What substance contains in a test tube, when heated with ninhidrin acquires got a purple color? *protein *vitamin *nucleotide *coenzyme *polysaccharide. The xantoprotein reaction is provided by the α-amino acid *lysine *asparagine *valine *isoleucine *phenylalanine  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из. In which form does leucine (pI=6.0) predominantly exist as an ion in a solution of 0.01 M NaOH? *zwitter-ion *cationic *anionic *bipolar ion *uncharged. What type of bond occurs between the side chains of phenylalanine (2-amino-3-phenylpropanoic acid) and valine (2-amino-3-methylbutanoic acid)? *ionic *hydrogen *hydrophobic *anhydride *disulfide. What type of bond occurs between the side chains of arginine (2-amino-5-guanidinopentanoic acid) and glutamic acid (2-aminopentanedioic acid)? *hydrogen *anhydride *hydrophobic *ionic *disulfide. Choose correct characteristics of the structure of the amino acid *non-essential amino acid *α-amino acid with one center of chirality *D-amino acid *polar, ionogenic amino acid *polar, non-ionogenic amino acid. Choose correct characteristics of the structure of the amino acid  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *basic amino acid *zwitterion *D-amino acid *non-essential amino acid *polar, non-ionogenic amino acid. What would be the value (pI = 4.8) of pH of the solution (if albumin molecules are positively charged and go to the cathode by electrophoresis)? * * * , * *. Which -amino acid forms lactic acid (2-hydroxypropanoic acid) due to hydroxylation (hydrolytic deamination)? *alanine ( -aminopropionic acid) *valine ( -aminoisovaleric acid) *methionine ( -amino- -methylthiobutyric acid) *serine ( -amino- -hydroxypropionic acid) *phenylalanine ( -amino- -phenylpropionic acid). What reaction has an oxo acid as a product? *esterification of threonine with phosphoric acid *non-oxidative deamination of aspartic acid *decarboxylation of histidine *oxidative deamination of glutamic acid *deamination of isoleucine with НNO2. What reaction has an unsaturated acid as a product? *esterification of threonine with phosphoric acid *non-oxidative deamination of aspartic acid *decarboxylation of histidine *oxidative deamination of glutamic acid *deamination of isoleucine with НNO. Which amino acids are formed during the acid hydrolysis of the tripeptide given follow? *valine, isoleucine, alanine  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *isoleucine, valine, alanine *alanine, leucine, valine *leucine, valine, alanine *valine, leucine, alanine. What are the amino acids present in the following tripeptide? *glycine, methionine, serine *methionine, glycine, serine *serine, glycine, methionine *serine, methionine, glycine *methionine, serine, glycine. Statement that correspond to the structure and properties of phenylalanine is *has amphoteric properties *relates to a basic amino acids *does not belong to essential -amino acids *forms an ester with phosphoric acid *refers to heterocyclic -amino acids Carbohydrates 1. How many chiral carbon atoms are present in glucose? * * * * *. How many optical isomers can the oxo form of D-fructose have? * * * * *. What is the name of the given structure?  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *D-galactose *D-fructose *D-mannose *D-glucose *D-xylose 4. Which monosaccharide does the given structure correspond to? *D-mannose *D-glucose *D-fructose *D-xylose *D-galactose 5. Which monosaccharide corresponds to the structure in the form of the given cyclic hemiacetal? * -D-fructofuranose * -D-galactofuranose * -D-fructofuranose * -D-ribofuranose * -D-xylofuranose 6. What is the name of the given structure?  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *pentanoic acid *hyaluronic acid *mannuronic acid *glucuronic acid *galacturonic acid 7. Which stereoisomer is -D-galactopyranose to the -D-mannopyranose? *anomer *epimer *racemate *diastereomer *enantiomer. D-fructose and L-fructose are… *enantiomers *diastereomers *epimers *anomers *structural isomers. Which pair of carbohydrates would be called epimers? *L-mannose and D-mannose *D-glucose and D-fructose *D-galactose and D-glucose *D-galactose and D-mannose *D-glucose and L-glucose. What statement is correct for α- and β- anomers? *they are enantiomers *they exist in acyclic form *they differ in configuration of anomeric carbon atom *they are acetals *their aqueous solutions are resistant to mutarotation 11. What product is formed when a monosaccharide reacts with an alcohol in the presence of anhydrous hydrogen chloride? *ether *ester  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *hemiacetal *glycoside *acid 12. What of the following products are formed by the hydrolysis of methyl- -D-glucopyranoside in acidic medium? *methanol and glucose *methylamine and glucose *methanol and methylglycoside *methanoic acid and glucose *methanol and gluconic acid 13. What compound is formed in the reduction of D-galactose? *ribitol *xylitol *sorbitol *mannitol *dulcitol 14. The blue chelate complex is formed by the reaction of D-glucose with a reagent… *CH ОН/НСl, without heating *С Н ОН/Н+, with heating *Cu(OH) /NaOH, without heating *Cu(OH) /NaOH, with heating *[Ag(NH ) ]OH, with heating. Which oxidant transforms aldose into aldaric acid? *copper oxide *bromine water *copper sulfate *nitric acid *copper hydroxide 16. What product is formed when monosaccharides are reduced? *polyatomic alcohols *hydroxy acids *ethers *glycosides *amino alcohols. Which of the following reagent can be used to distinguished sucrose from maltose? *methyliodide *dimethyl sulfate *Fehling's reagent  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *nitrous acid *acetic anhydride. Which compounds are formed of hydrolysation of maltose? *glucose and mannose *glucose and fructose *galactose and glucose *galactose and fructose * molecules of glucose. Which monosaccharides form sucrose by condensation? * -D-glucopyranose + -D-glucopyranose * -D-glucopyranose + -D-glucopyranose * -D-glucopyranose + -D-glucopyranose * -D-glucopyranose + -D-fructofuranose * -D-galactopyranose + -D-glucopyranose 20. Which kind of glycosidic linkage present in amylopectin is absent in amylose? * - , * - , * - , * - , * - ,. Monosaccharide is *maltose *sucrose *fructose *starch *heparin. Disacchride is *ribose *amylose *glycogen *sucrose *galactose. Heteropolysaccharide *glycogen *heparin *amylose *amylopectin *starch  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из. Aldohexose is *deoxyribose *galactose *fructose *ribose *xylose. Statement which corresponds to the propertiers of laсtose is *consists of two glucose residues *contains an ( ) glycosidic bond *does not have reducing properties *enters into a hydrolysis reaction in the presence of alkali *has the ability to a cyclo-oxotautomerism Saponifiable and nonsaponifiable lipids. Which of the following fatty acids is essential? * * * * *. What is the formula for palmitic acid? * * * * * 3. The triacylglycerol with highest iodine number is *trioleoylglycerol *1-linolenoyl-2,3-dioleoylglycerol *tripolmitoylglycerol *1-oleoyl-2,3-dipalmitoylglycerol *1,2-dilinoleoyl-3-stearoylglycerol. Which compound is a simple saponifiable lipid? *cholic acid *triacylglyceride *phosphoglyceride *ergosterol  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *cholesterol. Solid at room temperature is *triolein *trilinolein *dioleopalmitin *dilinoleostearin *palmitodistearin. What title corresponds to the following compound? *1-oleoyl-2-palmitoyl-3-stearoyl glycerol *1-oleoyl-2-stearoyl-3-palmitoyl glycerol *1-oleoyl-2-stearoyl-3-linolenoyl glycerol *1-linoleoyl-2-oleoyl-3-palmitoyl glycerol *1-linolenoyl-2-palmitoyl-3-stearoyl glycerol. Product of complete hydrogenation from 3-linolenoyl-2-palmitoyl-1-stearoylglycerol is * 3- oleoyl-2-palmitoyl-1-stearoylglycerol * 1,2,3-tripalmitoylglycerol * 2-palmitoyl-1,3-distearoylglycerol * 1,2,3-tristearoylglycerol * 3-linoleoyl-2-palmitoyl-1-stearoylglycerol. Which of the following compounds are formed by acidic hydrolysis of triacylglycerol? *glycerol, oleic, linoleic, stearic acid *glycerol, stearic, linolenic, linoleic acid *glycerol, sodium oleate, sodium stearate, sodium palmitate *glycerol, oleic acid, stearic acid, palmitic acid *glycerol, sodium stearate, sodium linolenoate, sodium linoleate. Which of the following compounds are formed by the saponification of triacylglycerol?  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *glycerol, sodium stearate, sodium linolenoate, sodium linoleate *glycerol, oleic acid, palmitic acid, stearic acids *glycerol, sodium oleate, sodium palmitate, sodium stearate *glycerol, stearic, linolenic, linoleic acids *glycerol, stearic, oleic, linoleic acids 10. How many moles of hydrogen are required for the complete hydrogenation of 1 mole of the given fat? * * * * *. What is the structure of the amino alcohol, which is part of phosphatidylcholine? * ( ) * * ( ) * ( ) * ( ). Which aminoalcohol is contained in phosphatidylethanolamine? *serine *choline *taurine *colamine *propanolamine. What is the product of the reaction ? *phosphatidylserine *colamincefalin *glycerophosphate *serincefalin *lecithin. What kind of bond will hydrolyze in phosphatidylethanolamine?  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *amide bond *peptide bond *glycosidic bond *ester bond *ether bond 15. What reaction can be used to obtain phosphatidylethanolamine from phosphatidylserine? *deamination *esterification *decarboxylation *alkylation *dehydrogenation. With what compound does cholic acid interact to form glycocholic acid? * * ( ) * ( ) * ( ) * ( ) ( ). What is the product of the reaction of cholic acid with taurine? *ester *ether *anhydride *amide *amine. What bond may hydrolyze in glycocholic acid? *amide bond  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *hydrogen bond *glycosidic bond *ester bond *ether bond. Which statement characterizes the structure and properties of ergosterol? *can form an ester *isomerizes to vitamin *is a primary alcohol *undergoes hydrolysis reaction *refers to the saponifiable lipids. Correct statement characterizing saturated fatty acids of lipids is *they are liquid substances at room temperature *they contain an even number of carbon atoms *they do not show the properties characteristic of carboxylic acids *they take part in addition reactions *they have cis-, trans- configurations. Which statement characterizes the structure and properties of the linolenic acid? *it is an non-essential fatty acid *in the hydrocarbon radical there are two -bonds *at room temperature it is solid *in the hydrocarbon radical contains 15 carbon atoms *contains an even number of carbon atoms. Which statement characterizes the structure and properties of 1-oleoyl-2-palmitoyl-3- stearoylglyserol? *liquid consistency *contains the essential fatty acids *refers to complex saponifiable lipids *can be hydrolyzed in acidic and alkaline medium *contains one saturated acid and two unsaturated acids  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из Heterocyclic compounds. Nucleic bases and nucleotides 1. Which product is formed by the reaction: [ ] *pyridine *pyrroline *pyrimidine *piperidine *pyrrolidine 2. The fused ring heterocycle is *purine *pyran *pyrazole *imidazole *pyrrolidine. There is N-H acidic reaction center in a molecule of *furan *thiophene *pyrrol *pyrimidine *pyridine. Which heterocycle will react with acids? pyridine pyrrole thiophene indole furan. What is the product of the reaction: ? *pyridine-2-sulfonic acid *pyridine-3-sulfonic acid *pyridine-4-sulfonic acid *pyridine-2,4-disulfonic acid *pyridine-3,4-disulfonic acid. Purine molecule consists of structures *pyrimidine and imidazole *pyrimidine and pyrazole *imidazole and pyrazole *two benzene molecules *pyridine and pyrrole  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из 7. What is the product of the reaction: -methylpyridine + [O] *pyridine-2-carboxylic acid *N-methylpyridinium hydroxide *isonicotinic acid *nicotinic acid * -hydroxypyridine. Nicotinic acid is derivative of *pyran *purine *pyrazole *pyridine *pyrimidine 9. Which compound is an alkaloid? *hypoxanthine *uric acid *caffeine *xanthine *purine. Wich heterocycle is six-membered? *purine *pyrimidine *pyrazole *imidazole *pyrrolidine 11. Which nucleic base are adenine and guanine derivatives of? *pyrimidine *quinoline *pyrazole *purine *pyridine. Nucleotides are characterized by types of bonds … *ester and N-glycosidic *ester and anhydride *anhydride and ether *phosphodiester and N-glycosidic *anhydride and N-glycosidic 13. What name corresponds to the following purine derivative in lactam tautomeric form?  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *guanine (2-amino-6-oxopurine) *uracil (2,4-dioxopyrimidine) *thymine (2,4-dioxo-5-methylpyrimidine) *cytosine (4-amino-2-oxopyrimidine) *adenine (6-aminopurine). What bond is formed by the phosphorylation of GDF (guanozine- -diphosphate)? *amide *anhydrite *N-glycosidic *O-glycosidic *ester. Which type of bond forms during the interaction of uridine with phosphoric acid? *amide *anhydrite *N-glycosidic *O-glycosidic *ester. Which type of bond forms during the interaction of uracil with D - ribose? *amide *anhydrite *N-glycosidic *ester *O-glycosidic. What is the name of compound with following structure?  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из *guanosine *adenosine *thymidine *cytosine *uridine 8. What products are formed by complete hydrolysis of thymidine- /-phosphate in acidic medium? *thymine, 2-deoxy- -D-ribofuranose, phosphoric acid *thymine, -D-ribofuranose, phosphoric acid *timidinmonophosphate, phosphoric acid *thymine, 2-deoxy -D-ribofuranose *timidinmonophosphate 19. What products are formed by the hydrolysis reaction of uridine in an acidic environment? *uracil, deoxyribose *uridylic acid *uridine monophosphate *uracil, ribose *deoxyribose. Pyrimidine base is *purine *uracil *guanine *pyrimidine *adenine  «С.Ж. АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА» Редакция: Chemistry department Training tests Страница из. A deoxyribonucleotide is *guanosine-5'-phosphate *thymidine-5'-phosphate *5'-adenylic acid *deoxycytidine *deoxyadenosine. Which compound of the following is able to form a complementary pair with cytosine? *2,4-dioxopyrimidine *4-amino-2-oxopyrimidine *6-aminopurine *2-amino-6-oxopurine *6-hydroxypurine. Which of the following statements are correct with respect to the structure and properties of adenine *it forms a complementary pair with thymine *it has three hydrogen bonds with cytosine in the DNA chain *it is formed by alkaline hydrolysis of AMP *it is capable of lactam-lactym tautomerism *it is a derivative of pyrimidine. Which of the following statements are correct with respect to the structure and properties of nicotine? *it is derivative of pyrroline *it contains pyridine and pyrrole rings *it forms salt with organic acids *it is structural fragment of NAD+ *it contains sp and sp hybridized nitrogen atoms Head of the Chemistry Department __________________ D. 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