Thyroid Drugs Part 4.docx

\#\#\# \*\*Slide 19: Hyperthyroidism - Overview\*\* 1\. \*\*Which of the following is the most common cause of hyperthyroidism?\*\* \- A. Thyroid cancer \- B. Graves\' disease \- C. Toxic multinodular goiter \- D. Drug-induced thyroiditis \*\*Answer:\*\* B. Graves\' disease 2\. \*\*Which lab...

\#\#\# \*\*Slide 19: Hyperthyroidism - Overview\*\* 1\. \*\*Which of the following is the most common cause of hyperthyroidism?\*\* \- A. Thyroid cancer \- B. Graves\' disease \- C. Toxic multinodular goiter \- D. Drug-induced thyroiditis \*\*Answer:\*\* B. Graves\' disease 2\. \*\*Which lab finding is typical in hyperthyroidism?\*\* \- A. Elevated TSH \- B. Suppressed TSH, elevated T3 and T4 \- C. Decreased T3 and T4 levels \- D. Elevated reverse T3 \*\*Answer:\*\* B. Suppressed TSH, elevated T3 and T4 3\. \*\*Which symptom is characteristic of hyperthyroidism?\*\* \- A. Cold intolerance \- B. Bradycardia \- C. Heat intolerance \- D. Weight gain \*\*Answer:\*\* C. Heat intolerance \-\-- \#\#\# \*\*Slide 20: Graves\' Disease\*\* 1\. \*\*What is the primary immunologic feature of Graves\' disease?\*\* \- A. Production of thyroid-stimulating antibodies (TSI) \- B. Production of anti-thyroid peroxidase antibodies \- C. Decreased iodine uptake \- D. Destruction of thyroid follicular cells \*\*Answer:\*\* A. Production of thyroid-stimulating antibodies (TSI) 2\. \*\*Which eye-related condition is associated with Graves\' disease?\*\* \- A. Ptosis \- B. Orbital myositis \- C. Exophthalmos \- D. Optic neuritis \*\*Answer:\*\* C. Exophthalmos 3\. \*\*Which test can be used to confirm the diagnosis of Graves\' disease?\*\* \- A. Anti-thyroid peroxidase antibodies \- B. Radioactive iodine uptake (RAIU) test \- C. Serum cortisol levels \- D. Thyroid ultrasound \*\*Answer:\*\* B. Radioactive iodine uptake (RAIU) test \-\-- \#\#\# \*\*Slide 21: Treatment of Hyperthyroidism\*\* 1\. \*\*Which of the following is a first-line treatment for hyperthyroidism?\*\* \- A. Methimazole \- B. Propylthiouracil (PTU) \- C. Levothyroxine \- D. Liothyronine \*\*Answer:\*\* A. Methimazole 2\. \*\*Which of the following hyperthyroid treatments is contraindicated in the first trimester of pregnancy?\*\* \- A. Radioactive iodine \- B. Methimazole \- C. Propylthiouracil (PTU) \- D. Beta-blockers \*\*Answer:\*\* B. Methimazole 3\. \*\*What is the primary action of thioamide drugs (e.g., methimazole, PTU) in treating hyperthyroidism?\*\* \- A. Block thyroid hormone release \- B. Inhibit thyroid hormone synthesis \- C. Increase iodine uptake by the thyroid \- D. Decrease peripheral conversion of T4 to T3 \*\*Answer:\*\* B. Inhibit thyroid hormone synthesis \-\-- \#\#\# \*\*Slide 22: Methimazole and Propylthiouracil (PTU)\*\* 1\. \*\*Methimazole is preferred over PTU due to which of the following advantages?\*\* \- A. Lower incidence of side effects \- B. Safer for use during pregnancy \- C. Longer half-life and once-daily dosing \- D. Better efficacy for treating thyroid cancer \*\*Answer:\*\* C. Longer half-life and once-daily dosing 2\. \*\*Which of the following is a serious side effect of PTU?\*\* \- A. Hepatotoxicity \- B. Hyperkalemia \- C. Osteoporosis \- D. Nephrotoxicity \*\*Answer:\*\* A. Hepatotoxicity 3\. \*\*In what situation is PTU preferred over methimazole?\*\* \- A. During the first trimester of pregnancy \- B. In patients with liver disease \- C. In patients with renal failure \- D. For long-term therapy in children \*\*Answer:\*\* A. During the first trimester of pregnancy \-\-- \#\#\# \*\*Slide 23: Radioactive Iodine Therapy\*\* 1\. \*\*Which of the following is a common side effect of radioactive iodine therapy for hyperthyroidism?\*\* \- A. Hypothyroidism \- B. Hypercalcemia \- C. Weight gain \- D. Hyperkalemia \*\*Answer:\*\* A. Hypothyroidism 2\. \*\*Which patient population should avoid radioactive iodine therapy?\*\* \- A. Men with prostate cancer \- B. Women who are pregnant or breastfeeding \- C. Children under 18 years of age \- D. Patients with autoimmune disorders \*\*Answer:\*\* B. Women who are pregnant or breastfeeding 3\. \*\*How long should a patient wait to conceive after receiving radioactive iodine therapy?\*\* \- A. 1 month \- B. 3 months \- C. 6 months \- D. 12 months \*\*Answer:\*\* C. 6 months \-\-- \#\#\# \*\*Slide 24: Beta-blockers in Hyperthyroidism\*\* 1\. \*\*What is the primary use of beta-blockers in the treatment of hyperthyroidism?\*\* \- A. Reduce thyroid hormone production \- B. Alleviate symptoms such as tachycardia and tremors \- C. Block iodine uptake \- D. Inhibit thyroid-stimulating antibodies \*\*Answer:\*\* B. Alleviate symptoms such as tachycardia and tremors 2\. \*\*Which beta-blocker is most commonly used in the management of hyperthyroid symptoms?\*\* \- A. Propranolol \- B. Metoprolol \- C. Atenolol \- D. Labetalol \*\*Answer:\*\* A. Propranolol 3\. \*\*In addition to reducing heart rate, how do beta-blockers assist in hyperthyroidism management?\*\* \- A. Increase T4 production \- B. Decrease TSH secretion \- C. Block peripheral conversion of T4 to T3 \- D. Increase iodine uptake \*\*Answer:\*\* C. Block peripheral conversion of T4 to T3