Tableau Drugs PDF

+-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Drug | Funct | Admin | Mecha | Actio | ½ | ADR | Inter | Other | | Name | ion | istra | nism | n | Life | | actio | s | | | | tion | | | | | n | | +---...

+-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Drug | Funct | Admin | Mecha | Actio | ½ | ADR | Inter | Other | | Name | ion | istra | nism | n | Life | | actio | s | | | | tion | | | | | n | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Tetro | Neuro | | Bocks | Paral | | | | | | dotox | toxin | | Na | ysis | | | | | | in | (puff | | chann | | | | | | | | er | | els | Resp | | | | | | | fish) | | | failu | | | | | | | | | | re | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | **Bat | Cardi | | Keep | Convu | | | | | | racho | otoxi | | K | lsion | | | | | | toxin | c | | chann | | | | | | | ** | neuro | | els | Spasm | | | | | | (**BT | toxic | | open | s | | | | | | X**) | (frog | | = | | | | | | | | /fish | | persi | Paral | | | | | | | ) | | stent | ysis | | | | | | | | | depol | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | **Sna | | | Block | Ø m. | | | | | | ke** | | | s | contr | | | | | | **ven | | | Ach | actio | | | | | | om** | | | r. | n | | | | | | | | | | | | | | | | | | | Degra | m. | | | | | | | | | des | weakn | | | | | | | | | Ach | ess | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Adren | -\>Ca | IV, | Catec | β1 = | | Panic | | Ø | | aline | rdiac | SC, | holam | Cardi | | Anxie | | cross | | / | arres | IM, | ine | ovasc | | ty | | BBB | | Epine | t | inhal | adren | | | Tremo | | | | phrin | | ation | ergic | Vasoc | | r | | | | e | Heart | | | onstr | | Cereb | | | | | block | Ø | non-s | ictio | | rovas | | | | | | oral | elect | n | | c | | | | | Shock | | ive | (high | | Arrhy | | | | | Haemo | | α | doses | | thmia | | | | | rrhag | | (high | ) | | s | | | | | es | | doses | | | | | | | | | | ) | ↑ HR, | | | | | | | Nasal | | β | BP, | | | | | | | decon | | (low | systo | | | | | | | gesta | | doses | le, | | | | | | | nts | | ) | contr | | | | | | | | | | actio | | | | | | | Anaes | | inhib | n | | | | | | | thesi | | it | force | | | | | | | a | | β2 | | | | | | | | | | (alle | β2 = | | | | | | | Anaph | | rgy) | Smoot | | | | | | | ylaxi | | | h | | | | | | | s | | | m | | | | | | | (alle | | | /Meta | | | | | | | rgy) | | | bo | | | | | | | | | | | | | | | | | Angio | | | Bronc | | | | | | | -oede | | | hodil | | | | | | | ma | | | atati | | | | | | | | | | on | | | | | | | | | | | | | | | | | | | | Uteri | | | | | | | | | | ne | | | | | | | | | | contr | | | | | | | | | | actio | | | | | | | | | | n | | | | | | | | | | | | | | | | | | | | GI | | | | | | | | | | relax | | | | | | | | | | | | | | | | | | | | Hyper | | | | | | | | | | glyce | | | | | | | | | | mic | | | | | | | | | | Lipol | | | | | | | | | | ysis | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | NA / | -\>Lo | IV, | Agoni | Vasoc | | Tachy | | Ø | | NE | cal | IM | st | onstr | | cardi | | cross | | | bleed | | α | ictio | | a | | BBB | | | ing, | | (spe) | n | | | | | | | HypoT | | + β | | | Arrhy | | Quick | | | , | | | ↑ BP | | thmia | | elimi | | | Anaph | | | | | s | | natio | | | ylact | | | ↑ | | | | n | | | ic | | | Rate/ | | Hyper | | | | | shock | | | Contr | | T | | | | | , | | | actio | | (necr | | | | | | | | n | | osis/ | | | | | Topic | | | force | | bleed | | | | | al | | | | | ing) | | | | | nasal | | | ↓GI | | | | | | | decon | | | mobil | | | | | | | gesta | | | ity | | | | | | | nt | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Dopam | | | Small | Vasod | | | | | | ine | | | doses | ilata | | | | | | | | | = D1 | tion | | | | | | | | | r. | D1 | | | | | | | | | (rena | (smal | | | | | | | | | l/hea | l | | | | | | | | | rt) | doses | | | | | | | | | | ) | | | | | | | | | Moder | | | | | | | | | | ate | Vasoc | | | | | | | | | = | onstr | | | | | | | | | β1r. | ictio | | | | | | | | | (iono | n | | | | | | | | | tropi | α1 | | | | | | | | | c, | | | | | | | | | | chron | (high | | | | | | | | | otrop | doses | | | | | | | | | ic) | ) | | | | | | | | | | | | | | | | | | | High | ↓ | | | | | | | | | = α1 | Renal | | | | | | | | | r. | BF | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Napha | | Topic | α 1 | Vasoc | | | | | | zolin | | al | Agoni | onstr | | | | | | e | | | st | ictio | | | | | | | | | | n | | | | | | | | | | eye | | | | | | | | | | nose | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Pseud | -Cold | | α 1 | Bronc | | | | Combi | | oephe | | | Agoni | hodil | | | | ne | | drine | -Alle | | st | atato | | | | antih | | | rgic | | | r | | | | istam | | | rhini | | | | | | | inic | | | tis | | | | | | | + | | | | | | | | | | antit | | | | | | | | | | ussiv | | | | | | | | | | e | | | | | | | | | | NSAID | | | | | | | | | | s | | | | | | | | | | (dext | | | | | | | | | | romet | | | | | | | | | | horph | | | | | | | | | | an) | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Pheny | -Deco | | α 1 | | | | | | | lprop | ngest | | Agoni | | | | | | | anola | ant | | st | | | | | | | mine | | | | | | | | | | | -Cold | | | | | | | | | Xylom | /coug | | | | | | | | | etazo | h | | | | | | | | | line | | | | | | | | | | | | | | | | | | | | Oxyme | | | | | | | | | | tazol | | | | | | | | | | ine | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Pheny | -Hypo | Paren | Selec | ↑BP | | Photo | | Resis | | lephr | volae | teral | tive | | | sensi | | tant | | ine | mic | | synth | Refle | | tive | | MAO | | | shock | Topic | etic | x | | | | COMT | | | | al | direc | brady | | Conju | | | | | -Sinu | | t | cardi | | nctiv | | Combi | | | sitis | | α 1 | a | | al | | natio | | | + | | Agoni | Midri | | hyper | | n | | | Rhini | | st | asis | | emia | | Dextr | | | tis | | | | | | | ometh | | | | | | Nasal | | Hyper | | orpha | | | -Midr | | | decon | | sensi | | n | | | iatic | | | gesti | | tivit | | = | | | | | | on | | y | | Antit | | | | | | | | | | ussiv | | | | | | | | | | e | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Cloni | -Opio | | α 2 | ↓BP + | | ↓ | Ø | ↑ | | dine | id/Al | | Agoni | CO | | ocula | breas | doses | | | cohol | | st | | | r | t | = | | | withd | | | ↓ | | BP | cance | | | | rawal | | relea | ocula | | | r | \- | | | | | se | r | | ↓ | | feedb | | | | | NA | hyper | | flush | | ack | | | | | | T | | ing | | = - | | | | | | | | menop | | NA | | | | | | ↓ | | ause | | | | | | | | menau | | ↓ | | | | | | | | pose | | migra | | | | | | | | flush | | ine | | | | | | | | | | | | | | | | | | ↓ | | | | | | | | | | migra | | | | | | | | | | ine | | | | | | | | | | | | | | | | | | | | -\>-A | | | | | | | | | | nti-h | | | | | | | | | | ypert | | | | | | | | | | ensiv | | | | | | | | | | e | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Dobut | -Card | | β1 | | | | | | | amine | iogen | | agoni | | | | | | | | ic | | st | | | | | | | | shock | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Salbu | -Bron | Inhil | Selec | Bronc | 2-6h | | | | | tamol | chial | ator | tive | hodil | | | | | | | asthm | | | atati | | | | | | Terbu | a | | β 2 | on | | | | | | talin | | | Agoni | | | | | | | e | -Atta | | st | | | | | | | | ck | | | | | | | | | Salme | | | | | | | | | | terol | -Prem | | | | | | | | | | ature | | | | | | | | | (Form | labor | | | | | | | | | otero | (salb | | | | | | | | | l) | utamo | | | | | | | | | | l) | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Ritod | -Uter | | β 2 | | | | | ØMAO | | rine | ine | | Agoni | | | | | COMT | | | relax | | st | | | | | | | | ant | | | | | | | Cross | | | | | | | | | | BBB | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Mirab | -Blad | | β 2 | | | | | | | egron | der | | Agoni | | | | | | | | | | st | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Ephed | -Alle | Oral, | Mixed | α ↑ | | | Ø | Cross | | rine | rgic | Topic | actio | BP | | | MAOIs | BBB | | | Rhini | al | n | activ | | | antid | | | (Amph | tis | | | e | | | epres | | | etami | | | Ø | CNS | | | sant | | | ne, | -Anti | | recyc | Vasoc | | | -- | | | Tyram | flu, | | le | onstr | | | Tyram | | | ine) | | | NT | ictio | | | ine | | | | -Nasa | | | n | | | = | | | | l | | \+ | | | | hyper | | | | decon | | relea | β ↑ | | | T | | | | gesta | | se | heart | | | crisi | | | | nt | | NA | contr | | | s | | | | (Xylo | | | actio | | | | | | | meraz | | | n | | | -\>Ch | | | | oline | | | | | | eese | | | | ) | | | Bronc | | | effec | | | | | | | hodil | | | t | | | | | | | atati | | | | | | | | | | on | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Amphe | -ADHD | | Mixed | Alert | | Depen | | Short | | tamin | | | actio | ness | | dency | | lasti | | e | -Narc | | n | | | | | ng | | | oleps | | | Eupho | | Toler | | | | | y | | α/β | ria | | ance | | Banne | | | | | agoni | | | | | d | | | -Epil | | st | Talk | | Anore | | / | | | epsy | | | activ | | xia | | dope | | | | | activ | eness | | | | test | | | -Park | | e | | | | | | | | inson | | CNS | ↑ | | | | | | | ism | | | work | | | | | | | | | \+ | capac | | | | | | | | | relea | ity | | | | | | | | | se | | | | | | | | | | NA | ↑ | | | | | | | | | | physi | | | | | | | | | | cal | | | | | | | | | | activ | | | | | | | | | | ity | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Pheno | Phaeo | Oral | Irrev | Vasod | 12h | Ortho | | | | xyben | chrom | | ersib | ilata | | stati | | | | zamin | ocyto | | le | tion | | c | | | | e | ma | | Antag | | | hypoT | | | | | (tumo | | onist | HypoT | | | | | | | r | | α | | | Tachy | | | | | adren | | adren | Tachy | | cardi | | | | | al | | ergic | cardi | | a | | | | | g) | | | a | | | | | | | | | | | | Nasal | | | | | | | | Facil | | conge | | | | | | | | itate | | stion | | | | | | | | urina | | | | | | | | | | tion | | Impot | | | | | | | | | | ence | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Phent | | | Antag | | | Ortho | | | | olami | | | onist | | | stati | | | | ne | | | α | | | c | | | | | | | adren | | | hypoT | | | | | | | ergic | | | | | | | | | | | | | Ergot | | | | | | | | | | ic | | | | | | | | | | deriv | | | | | | | | | | ative | | | | | | | | | | s | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Prazo | -Hype | | Selec | Vasod | 4h | Same | | | | sin | rT | | tive | ilata | | | | | | | | | α1 | tion | | | | | | | | | antag | | | | | | | | | | onist | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Doxaz | -Seve | | Selec | | | | | | | osin | re | | tive | | | | | | | | Hyper | | α1 | | | | | | | | T | | antag | | | | | | | | | | onist | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Teraz | | | Selec | | | | | | | osin | | | tive | | | | | | | | | | α1 | | | | | | | | | | antag | | | | | | | | | | onist | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Tamsu | Benig | | Selec | | | Impai | | | | losin | n | | tive | | | red | | | | | prost | | α1 | | | ejacu | | | | | atic | | antag | | | latio | | | | | hyper | | onist | | | n | | | | | troph | | | | | | | | | | y | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Yohim | | | Selec | | | | | | | bine | | | tive | | | | | | | | | | α2 | | | | | | | Idazo | | | antag | | | | | | | xan | | | onist | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Ergot | | | Ergot | | | | | | | amine | | | deriv | | | | | | | | | | ative | | | | | | | Dihyd | | | s | | | | | | | roerg | | | block | | | | | | | otami | | | α r. | | | | | | | ne | | | 5HTr | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | **β-b | -Angi | Oral | β | antih | | -Hear | | Ø for | | locke | na | Paren | antag | yperT | | t | | | | rs** | pecto | teral | onist | | | failu | | Asthm | | | ris | | | ↓HR, | | re | | a | | | | | | BP | | | | | | | -Myoc | | | | | -Brad | | AV | | | ardia | | | ↓cont | | ycard | | block | | | l | | | racti | | ia | | | | | infar | | | bilit | | | | Uncom | | | ction | | | y | | -Cond | | pensa | | | | | | | | uctio | | ted | | | -Arrh | | | ↓CO, | | n | | heart | | | ythmi | | | O2 | | block | | failu | | | a | | | | | | | re | | | | | | ↓intr | | -Bron | | | | | -Hear | | | aocul | | choco | | \~ | | | t | | | ar | | nstri | | Brady | | | failu | | | P | | ct° | | cardi | | | re | | | | | | | a | | | compe | | | ↓gluc | | -Rayn | | | | | nsate | | | ose | | aud's | | Insul | | | d | | | toler | | d | | in | | | | | | ance | | (cold | | dep | | | -Hype | | | | | extre | | diabe | | | rT | | | Ø | | mitie | | tes | | | | | | Lipol | | s) | | | | | -Glau | | | ysis | | | | Heart | | | coma | | | | | -CNS | | failu | | | (Timo | | | Bronc | | insom | | re | | | lol) | | | hocon | | nia | | | | | | | | stric | | | | Perip | | | -Anxi | | | tion | | -Depr | | heral | | | ety | | | (not | | essio | | vasc | | | | | | selec | | n | | | | | -Migr | | | tive) | | | | | | | aine | | | | | -Tire | | | | | proph | | | ↑ | | dness | | | | | ylact | | | Uteri | | | | | | | ic | | | ne | | -Dizz | | | | | | | | contr | | iness | | | | | -Beni | | | actio | | | | | | | gn | | | n | | -↓Lib | | | | | tumor | | | | | ido | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Propr | -Angi | | Non | β1 = | 4h | Bronc | | | | anolo | na | | selec | ↓CO | | hocon | | | | l | | | tive | | | stric | | | | | -Hype | | β1,β2 | β2 = | | t° | | | | Alpre | rT | | antag | Bronc | | | | | | nolol | | | onist | hocon | | Brady | | | | | -Card | | | stric | | cardi | | | | Oxpre | iac | | 90% | tion | | a | | | | nolol | dysrh | | bound | | | | | | | | ythmi | | | Relax | | Cardi | | | | | as | | Parti | perip | | ac | | | | | | | al | heral | | failu | | | | | -Anxi | | agoni | vasoc | | re | | | | | ety | | st | onstr | | | | | | | | | β r | ictio | | | | | | | -Trem | | (Alpr | n | | | | | | | or | | e | | | | | | | | | | / | | | | | | | | -Glau | | Oxpre | | | | | | | | coma | | ) | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Ateno | | | β1 | | | | | | | lol | | | selec | | | | | | | | | | tive | | | | | | | Nebiv | | | antag | | | | | | | olol | | | onist | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Labet | Pregn | | Mixed | | 4h | Postu | | | | alol | ancy | | actio | | | ral | | | | | hyper | | n | | | hypoT | | | | | T | | | | | | | | | | | | α/β | | | Bronc | | | | | | | antag | | | hocon | | | | | | | onist | | | stric | | | | | | | | | | tion | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Carve | Heart | | Mixed | | 10h | More | | | | dilol | failu | | actio | | | Heart | | | | | re | | n | | | failu | | | | | | | | | | re | | | | | | | α/β | | | | | | | | | | antag | | | Renal | | | | | | | onist | | | failu | | | | | | | | | | re | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | **α-m | Phaeo | | Inhib | Ø | | | | | | ethyl | chrom | | it | Synth | | | | | | p | ocyto | | tyros | esis | | | | | | tyros | ma | | ine | NA | | | | | | ine** | | | hydro | | | | | | | | | | xylas | | | | | | | | | | e | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Methy | Pregn | | | Ø | | | | | | ldopa | ancy | | | Synth | | | | | | | hyper | | | esis | | | | | | | T | | | NA | | | | | | | | | | | | | | | | | | | | -\>An | | | | | | | | | | ti-hy | | | | | | | | | | perte | | | | | | | | | | nsive | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | L-DOP | Ortho | | | Ø | | | | | | S | stati | | | Synth | | | | | | | c | | | esis | | | | | | | hypoT | | | NA | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Imipr | Depre | | Inhib | ↑ | 4h | Cardi | | | | amine | ssion | | it | \[Na\ | | ac | | | | | | | NET | ] | | dysrh | | | | | | | | | | ythmi | | | | | | | \~Atr | | | a | | | | | | | opine | | | | | | | | | | | | | OD | | | | | | | 95% | | | | | | | | | | bound | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Cocai | Anaes | | Inhib | ↑ | | Hyper | | Drug | | ne | thesi | | it | \[Na\ | | T | | abuse | | | a | | NET | ] | | | | | | | | | | | | Convu | | | | | | | Relea | | | ltion | | | | | | | se | | | | | | | | | | NA | | | Depen | | | | | | | | | | dance | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Tuboc | Ø PΣ | | Inhib | Flacc | | Resp | | | | urari | | | it | id | | paral | | | | ne | Neuro | | nicot | paral | | ysis | | | | | muscu | | inic | ysis | | | | | | Atrac | bloke | | ion | | | Bronc | | | | urium | rs | | chann | | | hospa | | | | | | | el | | | sm | | | | Mivac | Non | | skele | | | (Atra | | | | urium | depol | | tal | | | , | | | | | | | m | | | Miva) | | | | **Pan | M. | | | | | | | | | curon | relex | | (comp | | | hypoT | | | | ium** | ant | | etiti | | | | | | | (mAch | / | | ve | | | ↓ art | | | | r.) | Anest | | antag | | | P | | | | | hesia | | onist | | | (M2) | | | | | | | Ach) | | | (Tubo | | | | | | | | | | ) | | | | | | | | | | | | | | | | | | | | Tachy | | | | | | | | | | cardi | | | | | | | | | | a | | | | | | | | | | (Pan) | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Suxam | Ø PΣ | IV | Neuro | Flacc | | Cardi | | | | ethon | depol | (long | muscu | id | | ac | | | | ium | | er) | block | paral | | arres | | | | | M. | | ers | ysis | | t | | | | Succi | relax | | | | | | | | | nylch | ant | | Depol | m. | | Hyper | | | | oline | (shor | | | relax | | therm | | | | | t) | | Hydro | | | ia | | | | Dantr | | | xyliz | | | | | | | olene | Intub | | ed | | | Anaph | | | | | ation | | plasm | | | ylact | | | | | | | a | | | ic | | | | | Elect | | choli | | | shock | | | | | rocon | | neste | | | | | | | | vulsi | | rase | | | Paral | | | | | thera | | | | | ysis | | | | | py | | K+ | | | | | | | | | | relea | | | M. | | | | | Malig | | se | | | pain | | | | | nant | | | | | | | | | | hyper | | | | | ↑ eye | | | | | therm | | | | | P | | | | | ia | | | | | | | | | | | | | | | Brady | | | | | | | | | | cardi | | | | | | | | | | a | | | | | | | | | | | | | | | | | | | | Arryt | | | | | | | | | | hmias | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Trime | Ø PΣ | | Inhib | | | | | | | tafan | | | it | | | | | | | | | | nicot | | | | | | | | | | inic | | | | | | | | | | ion | | | | | | | | | | chann | | | | | | | | | | el | | | | | | | | | | post | | | | | | | | | | gangl | | | | | | | | | | ionar | | | | | | | | | | N | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Atrop | Inhib | oral | Compe | ↑HR,C | | Dry | Ø | All | | ine | it | | titiv | O | | mucou | Glauc | tissu | | | PΣ | | e | = | | s | oma | es | | (bell | effec | | Inhib | tachy | | | = ↑ | (lipo | | adonn | ts | | it | cardi | | Bloat | eye P | solub | | a | | | Musca | a | | ing | | le) | | berri | Brady | | rinic | | | | | | | es) | cardi | | r | Bronc | | Const | | Cross | | | a | | | hodil | | ipati | | BBB, | | (dead | (Atro | | | atati | | on | | Place | | ly | pine | | | on, | | | | nta, | | night | 4 M2) | | | ↓secr | | Mydri | | milk | | shade | | | | etion | | asis | | | | ) | Motio | | | | | | | Low | | | n | | | ↓Muco | | Blurr | | doses | | Scopo | sickn | | | cilia | | ed | | = | | lamin | ess | | | ry | | visio | | brady | | e | (Scop | | | clear | | n | | cardi | | | a) | | | ance | | | | a | | (blac | | | | (Atro | | Photo | | | | k | Antis | | | pine) | | phobi | | | | henba | pasmo | | | | | a | | | | ne) | dic | | | ↓ GI | | | | | | | (Scop | | | secre | | ↑ eye | | | | -\>Na | a | | | t°, | | P | | | | tural | M3) | | | motil | | | | | | alkal | | | | ity | | Tachy | | | | oid | Dilat | | | | | cardi | | | | | ation | | | Relax | | a | | | | | pupil | | | bladd | | | | | | | M5 | | | er | | Urina | | | | | | | | ↓ | | ry | | | | | | | | urine | | reten | | | | | | | | | | tion | | | | | | | | Anti- | | | | | | | | | | kinet | | ↑ | | | | | | | | ic | | doses | | | | | | | | (Scop | | = | | | | | | | | a) | | hallu | | | | | | | | | | cinat | | | | | | | | Anti- | | ion/ | | | | | | | | emeti | | delir | | | | | | | | c | | e | | | | | | | | | | | | | | | | | | Sedat | | Lost | | | | | | | | ion | | memor | | | | | | | | / | | y | | | | | | | | Drows | | | | | | | | | | iness | | | | | | | | | | | | | | | | | | | | Anti- | | | | | | | | | | Parki | | | | | | | | | | nsoni | | | | | | | | | | an | | | | | | | | | | | | | | | | | | | | Midri | | | | | | | | | | asis, | | | | | | | | | | Photo | | | | | | | | | | phobi | | | | | | | | | | a, | | | | | | | | | | Cyclo | | | | | | | | | | plegi | | | | | | | | | | a, | | | | | | | | | | ↑ eye | | | | | | | | | | P, | | | | | | | | | | ↓tear | | | | | | | | | | ,  | | | | | | | | | | sweat | | | | | | | | | | , | | | | | | | | | | saliv | | | | | | | | | | ary | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Methy | Inhib | '' | '' | " | | " | | '' | | lamph | it | | | | | | | | | etami | PΣ | | | | | | | | | ne | effec | | | | | | | | | | ts | | | | | | | | | Benza | | | | | | | | | | tropi | Parki | | | | | | | | | n | nson | | | | | | | | | | (Benz | | | | | | | | | (tert | atrop | | | | | | | | | iary | in) | | | | | | | | | amine | | | | | | | | | | ) | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | -Meth | Inhib | Paren | '' | " | | " | | " | | ylsco | it | teral | | | | | | | | polam | PΣ | | | | | | | | | ine | effec | Inhal | | | | | | | | | ts | ed | | | | | | | | -Scop | | (ipa. | | | | | | | | olami | Asthm | ) | | | | | | | | ne | a | | | | | | | | | butyl | (Ipra | | | | | | | | | bromi | tropi | | | | | | | | | de | um) | | | | | | | | | | | | | | | | | | | -Ipra | | | | | | | | | | tropi | | | | | | | | | | um | | | | | | | | | | | | | | | | | | | | -Tiot | | | | | | | | | | ropiu | | | | | | | | | | m | | | | | | | | | | | | | | | | | | | | (quat | | | | | | | | | | erny | | | | | | | | | | deriv | | | | | | | | | | ative | | | | | | | | | | s) | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Piren | Inhib | | | | | | | | | zepin | it | | | | | | | | | e | Ac | | | | | | | | | | secre | | | | | | | | | | t° | | | | | | | | | | (M1) | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Oxybu | Overa | | | | | | | | | tynin | ctive | | | | | | | | | | bladd | | | | | | | | | Tolte | er | | | | | | | | | rodin | | | | | | | | | | e | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Carba | Activ | Oral | Agoni | ↓BP, | | Nause | Ø Ach | Ø | | chol | ate | | st | CO | | a, | -- | Bronc | | | PΣ | | musca | | | Vomit | Metha | hial | | **Bet | | | rinic | Vasod | | ing, | choli | asthm | | hanec | -GI | | r | ilata | | Epiga | ne | a | | hol\* | Atony | | | tion | | stric | = | | | ** | , | | | | | pain, | inact | Gastr | | | Bladd | | | ↑GI | | Hyper | ivati | ic | | Ach/M | er | | | secre | | V, | on | ulcer | | ethac | | | | tion, | | Heada | by | | | holin | -Abdo | | | trans | | ches, | AchE | Coron | | e | diste | | | it, | | Bronc | | ary | | | nsion | | | cramp | | hocon | Ø | insuf | | (Chol | after | | | ing | | stric | Musca | ficie | | ine | surge | | | | | tion, | rine | ncy | | ester | ry | | | ↑ | | Visua | = | | | ) | | | | bladd | | l | toxic | Ø | | | | | | er | | prob, | ity | cross | | | | | | sphin | | HypoT | | BBB | | | | | | cter | | | | | | | | | | (urin | | | | | | | | | | at°) | | | | | | | | | | | | | | | | | | | | ↑Bron | | | | | | | | | | choco | | | | | | | | | | nstri | | | | | | | | | | ction | | | | | | | | | | | | | | | | | | | | ↑ | | | | | | | | | | Exocr | | | | | | | | | | ine | | | | | | | | | | secre | | | | | | | | | | t° | | | | | | | | | | | | | | | | | | | | Miosi | | | | | | | | | | s | | | | | | | | | | (↓ P) | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Musca | '' | '' | '' | '' | | '' | '' | '' | | rine | | | | | | | | | | | Glauc | IV | | | | Tremo | | Cross | | **Pil | oma | only | | | | r, | | BBB | | ocarp | | \* | | | | Ataxi | | | | ine | Xeros | | | | | a | | | | \*** | tomia | | | | | | | | | | | | | | | | | | | (Alka | Sjogr | | | | | | | | | loid | en's | | | | | | | | | natur | syndr | | | | | | | | | al) | ome | | | | | | | | | | (dry | | | | | | | | | | mouth | | | | | | | | | | ) | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | **Cev | '' | '' | '' | '' | | '' | '' | '' | | iment | | | | | | | | | | ine | | | | | | | | | | \*** | | | | | | | | | | | | | | | | | | | | (synt | | | | | | | | | | hetic | | | | | | | | | | ) | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Neost | Myast | SC + | Anti | | | | | | | igmin | henia | IV | AchE | | | | | | | e | gravi | | | | | | | | | | s | (Ø | \+ | | | | | | | Physo | | lipos | -\> | | | | | | | stigm | (Neo+ | olubl | PΣ | | | | | | | ine | Edro+ | e) | | | | | | | | | Pyrid | | Rever | | | | | | | Edrop | ostig | (Neo | se | | | | | | | honiu | mine) | + | non-d | | | | | | | m | | Edro) | epol | | | | | | | | Rever | | n | | | | | | | Amben | se | Topic | | | | | | | | onium | neuro | al | | | | | | | | | muscu | (lipo | | | | | | | | (reve | block | solub | | | | | | | | rsibl | | le) | | | | | | | | e) | Atony | (Phys | | | | | | | | | GI | os+Am | | | | | | | | | | be) | | | | | | | | | Glauc | | | | | | | | | | oma | Eye | | | | | | | | | | drop | | | | | | | | | Treat | | | | | | | | | | ment | | | | | | | | | | of | | | | | | | | | | Bella | | | | | | | | | | donna | | | | | | | | | | berri | | | | | | | | | | es | | | | | | | | | | (Phys | | | | | | | | | | ostig | | | | | | | | | | mine) | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Ecoth | Glauc | | Anti | | | | | Poiso | | iopha | oma | | AchE | | | | | ning | | te | | | | | | | | | | | | | \+ | | | | | | | Parat | | | -\> | | | | | | | ion | | | PΣ | | | | | | | | | | | | | | | | | (irre | | | | | | | | | | versi | | | | | | | | | | ble | | | | | | | | | | organ | | | | | | | | | | oP) | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Buspi | Anxie | | Serot | | | | | | | rone | ty | | onine | | | | | | | | | | 5HT | | | | | | | | | | 1a | | | | | | | | | | agoni | | | | | | | | | | st | | | | | | | | | | | | | | | | | | | | (sero | | | | | | | | | | tonin | | | | | | | | | | e) | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Fluox | Depre | | selec | | | | | | | etine | ssion | | tive | | | | | | | | | | serot | | | | | | | | | | onin | | | | | | | | | | uptak | | | | | | | | | | e | | | | | | | | | | inhib | | | | | | | | | | itors | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Tript | Migra | | 5-HT1 | | | | | | | ans | ine | | D | | | | | | | (Suma | | | | | | | | | | tript | | | | | | | | | | an) | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Pizot | | | Serot | | | | | | | ifen | | | onin | | | | | | | | | | | | | | | | | | | | 5 HT | | | | | | | | | | 2 | | | | | | | | | | antag | | | | | | | | | | onist | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Ondan | Chemo | | 5-HT3 | | | | | | | setro | thera | | antag | | | | | | | n | py-in | | onist | | | | | | | | duced | | | | | | | | | | emesi | | | | | | | | | | s | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | HDMA | Mood | | | | | | | | | (exta | alter | | | | | | | | | sy) | ation | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Ketam | Anest | | Antag | | | | | | | ine | hesia | | onist | | | | | | | | | | NMDA | | | | | | | | Depre | | | | | | | | | | ssion | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Meman | Parki | | Antag | | | | | | | tine | nson | | onist | | | | | | | | | | | | | | | | | | | | NMDA | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Bicuc | | | Antag | | | | | | | ullin | | | onist | | | | | | | e | | | GABA | | | | | | | | | | r | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Baclo | | | Agoni | Spast | | | | | | fen | | | st | icity | | | | | | | | | GABAb | | | | | | | | | | | Motor | | | | | | | | | | depre | | | | | | | | | | ssion | | | | | | | | | | | | | | | | | | | | Drug | | | | | | | | | | dep | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Stryc | | | Glyci | M. | | | | | | hnine | | | ne | spasm | | | | | | | | | antag | s | | | | | | | | | onist | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Methy | | | Antag | ↑ | | | | | | lxant | | | onist | wakef | | | | | | hine | | | A1 | ulnes | | | | | | (caff | | | | s | | | | | | eine) | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | TCA : | Depre | Oral | Inhib | Tricy | 10-80 | Ortho | Ø | Cross | | | ssion | (lipo | it | clic | h | stati | **cat | BBB | | Imipr | | solub | reupt | Antid | | c | echol | | | amine | Anxie | le) | ake | epres | | hypoT | amine | | | | ty | | dopam | sant | | | ** | | | Desip | | | ine | | | Palpi | (**A* | | | ramin | Hyper | | + | Anxio | | tatio | *) | | | e | activ | | serot | lytic | | n | + | | | | ity | | onin | / | | | **MAO | | | Clomi | (Imi) | | | Sedat | | Tachy | I** | | | prami | | | ↑ | ive | | cardi | = ↑ | | | ne | Enure | | \[5HT | | | a | effec | | | | sis | | \] | Analg | | | ts | | | Amitr | (pee) | | | esic | | Tremo | | | | iptyl | (Imi) | | ↑ | | | r | Ø | | | ine | | | \[NA\ | ↓emot | | | **ant | | | | Neuro | | ] | ional | | Convu | icoag | | | Nortr | genic | | | sympt | | lsion | ulant | | | iptyl | pain | | | oms | | | ** | | | ine | | | | | | Coma | (**wa | | | | (phan | | | ↓bio | | | rfari | | | Doxep | tom | | | sympt | | Weigh | n**) | | | in | limb) | | | oms | | t | = ↑ | | | | | | | | | gain | bleed | | | | Oncol | | | | | | ing | | | | ogica | | | | | Sweat | | | | | l | | | | | ing | Ø | | | | | | | | | | **alc | | | | Heada | | | | | Photo | ohol* | | | | ches | | | | | sensi | * | | | | | | | | | tivit | + | | | | | | | | | y | **ana | | | | | | | | | | esthe | | | | | | | | | GI | tic** | | | | | | | | | | | | | | | | | | | OD | Ø | | | | | | | | | | **ant | | | | | | | | | \~ | ihype | | | | | | | | | Atrop | rtens | | | | | | | | | ine | ive** | | | | | | | | | anti | | | | | | | | | | musc | Ø | | | | | | | | | | **Ora | | | | | | | | | | l | | | | | | | | | | contr | | | | | | | | | | acept | | | | | | | | | | ion** | | | | | | | | | | = | | | | | | | | | | inhib | | | | | | | | | | it | | | | | | | | | | metab | | | | | | | | | | o | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | SSRI | Depre | Oral | Inhib | Selec | 15-25 | Nause | Ø | \+ | | : | ssion | | it | tive | h | a | **TCA | commo | | | | | reupt | serot | | | ** | n | | Fluox | OC | | ake | onin | 24-96 | Anore | = | | | etine | disor | | serot | reupt | H | xia | ↓meta | Fewer | | (PROZ | ders | | onin | ake | (Fluo | | bo | ADR | | AC) | | | | inhib | ) | Insom | ↑toxi | | | | Bulim | | ↑\[ | itor | | nia | city | Anxio | | Parox | ia | | \] | | | | | lytic | | etine | | | | Antid | | Loss | Ø**MA | w/ | | | Panic | | | epres | | libid | OI** | sedat | | Cital | attac | | | sant | | o | = | ion | | opram | k | | | | | | serot | effec | | | | | | Anxio | | Serot | onin | t | | Sertr | Preme | | | lytic | | onin | syndr | | | aline | nstru | | | | | syndr | ome | | | | al | | | | | ome | = | | | | disor | | | | | | Hyper | | | | der | | | | | Safe | therm | | | | | | | | | OD | ia | | | | Prema | | | | | | | | | | ture | | | | | Ventr | CV | | | | ejacu | | | | | icula | colla | | | | latio | | | | | r | pse | | | | n | | | | | arrhy | | | | | | | | | | thmia | Death | | | | Migra | | | | | | | | | | ine | | | | | Aggre | | | | | | | | | | ssivi | | | | | Atypi | | | | | ty, | | | | | cal | | | | | suici | | | | | antip | | | | | de | | | | | sycho | | | | | | | | | | tic | | | | | | | | | | (Fluo | | | | | | | | | | ) | | | | | | | | | | | | | | | | | | | | Anxie | | | | | | | | | | ty | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | MAOI | Depre | | Inhib | Monoa | short | Ortho | Ø**Ty | | | A/B: | ssion | | it | mine | | stati | ramin | | | | | | monoa | oxida | | c | e** | | | (non- | Parki | | mine | se | | HypoT | = | | | selec | nson | | oxida | inhib | | | hyper | | | tive | (Sele | | se | itor | | Exces | T | | | -- | gilin | | ↑ | | | s | crisi | | | irrev | e) | | avail | Antid | | CNS | s | | | ersib | | | abili | epres | | stimu | | | | le | | | ty | sant | | lat° | ↑NA,↑ | | | ) | | | | | | | vasoc | | | | | | A = | | | Tremo | ontri | | | Phene | | | Serot | | | r, | ction | | | lzine | | | onin, | | | Excit | | | | | | | Metat | | | ement | -\>Ch | | | Trany | | | onine | | | , | eese | | | lcypr | | | , | | | Insom | effec | | | omine | | | A | | | nia, | t | | | | | | | | | OD, | : | | | Ipron | | | NA, | | | Convu | | | | iazid | | | Tyram | | | lsion | Heada | | | | | | ine, | | | | ches | | | Pargi | | | Dopam | | | ↑Appe | | | | lin | | | ine | | | tite | Chest | | | | | | | | | | pain | | | (A-se | | | B= | | | | | | | lecti | | | Phene | | | | Nause | | | ve | | | thyla | | | | a | | | -- | | | mine | | | | | | | rever | | | | | | | Vomit | | | sible | | | Dopam | | | | | | | ) | | | ine | | | | Sweat | | | | | | | | | | | | | Moclo | | | MAO B | | | | Tachy | | | bemid | | | inhib | | | | cardi | | | e | | | itor | | | | a | | | | | | (Sele | | | | | | | (B-Se | | | ) | | | | Strok | | | lecti | | | | | | | e | | | ve | | | | | | | | | | ) | | | | | | | Ø**TC | | | | | | | | | | A** | | | Seleg | | | | | | | : | | | iline | | | | | | | Serot | | | | | | | | | | onin | | | | | | | | | | syndr | | | | | | | | | | ome | | | | | | | | | | | | | | | | | | | | -\>** | | | | | | | | | | Σ | | | | | | | | | | drugs | | | | | | | | | | , | | | | | | | | | | antih | | | | | | | | | | istam | | | | | | | | | | inic, | | | | | | | | | | opioi | | | | | | | | | | ds** | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | SNRI | Depre | Oral | Inhib | Serot | | Heada | | | | : | ssion | | it | onin/ | | ches | | | | | | | serot | NA | | | | | | Venla | Anxie | | onin/ | uptak | | Insom | | | | faxin | ty | | NA | e | | nia | | | | e | | | reupt | inhib | | | | | | | Perim | | ake | itor | | Sex | | | | Desve | enopa | | ↑ \[ | | | dysfc | | | | nlafa | usal | | \] | Reduc | | t | | | | xine | syndr | | | e | | | | | | | ome | | | nause | | Dry | | | | Dulox | | | | a | | mouth | | | | etine | Neuro | | | | | | | | | | pathi | | | | | Dizzi | | | | | c | | | | | ness, | | | | | pain | | | | | sweat | | | | | (Duo) | | | | | | | | | | | | | | | ↓ | | | | | Urina | | | | | appet | | | | | ry | | | | | ite | | | | | incon | | | | | | | | | | tinen | | | | | OD: | | | | | ce | | | | | CNS | | | | | | | | | | Depre | | | | | | | | | | ssion | | | | | | | | | | | | | | | | | | | | Serot | | | | | | | | | | onin | | | | | | | | | | toxic | | | | | | | | | | ity | | | | | | | | | | | | | | | | | | | | Convu | | | | | | | | | | lsion | | | | | | | | | | | | | | | | | | | | CV, | | | | | | | | | | Hepat | | | | | | | | | | otoxi | | | | | | | | | | city | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Bupro | Nicot | | Inhib | Antid | | ↑ | | Ø | | pion | ine | | it | epres | | doses | | Abuse | | | addic | | NA | sant | | = | | poten | | | tion | | reupt | | | seizu | | tial | | | | | ake | | | re | | | | | | | ↑ \[ | | | | | | | | | | \] | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Rebox | Atten | | NA | Antid | | | | | | etine | tion | | reupt | epres | | | | | | | defic | | ake | sant | | | | | | Atomo | it | | selec | | | | | | | xetin | | | tive | | | | | | | e | Hyper | | | | | | | | | | activ | | | | | | | | | | ity | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | St. | Depre | | Inhib | Antid | | | | | | John' | ssion | | it | epres | | | | | | s | | | 5HT, | sive | | | | | | Wort | Anxie | | Dopam | | | | | | | = | ty | | ine, | Anxio | | | | | | Hyper | | | NA, | lytic | | | | | | forin | | | GABA, | | | | | | | | | | Gluta | | | | | | | | | | mate | | | | | | | | | | reupt | | | | | | | | | | ake | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Mirta | Depre | | Monoa | Antid | | | | | | zapin | ssion | | mine | epres | | | | | | e | | | r. | sant | | | | | | | | | Antag | | | | | | | Trazo | | | onist | | | | | | | done | | | | | | | | | | | | | Mirta | | | | | | | | | | : | | | | | | | | | | Block | | | | | | | | | | α2 + | | | | | | | | | | 5HT2C | | | | | | | | | | + H1 | | | | | | | | | | | | | | | | | | | | Trazo | | | | | | | | | | : | | | | | | | | | | 5HT2A | | | | | | | | | | + | | | | | | | | | | 5HT2C | | | | | | | | | | | | | | | | | | | | Ø 5HT | | | | | | | | | | reupt | | | | | | | | | | ake | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Agome | Sever | | Melat | Antid | short | Hepat | | | | latin | e | | onin | epres | | otoxi | | | | e | Depre | | agoni | sant | | city | | | | | ssion | | st | | | | | | | | | | | | | | | | | | Circa | | Antag | | | | | | | | dian | | onist | | | | | | | | distu | | MT1 + | | | | | | | | rbanc | | MT2 r | | | | | | | | e | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Lithi | Bipol | Oral | ↑NA/ | | | GI | Ø | | | um | ar | | 5HT | | | disco | Pregn | | | salts | disor | | relea | | | mfort | ant | | | | der | | se | | | | | | | Lithi | | | | | | Nause | | | | um | Alzhe | | | | | a | | | | carbo | imer | | | | | | | | | nate | | | | | | Vomit | | | | | | | | | | ing | | | | | | | | | | | | | | | | | | | | Diarr | | | | | | | | | | hea | | | | | | | | | | | | | | | | | | | | Anore | | | | | | | | | | xia | | | | | | | | | | | | | | | | | | | | Weigh | | | | | | | | | | t | | | | | | | | | | gain | | | | | | | | | | | | | | | | | | | | Polyu | | | | | | | | | | ria | | | | | | | | | | (anti | | | | | | | | | | diure | | | | | | | | | | tic) | | | | | | | | | | | | | | | | | | | | Tremb | | | | | | | | | | ling | | | | | | | | | | hands | | | | | | | | | | | | | | | | | | | | Thyro | | | | | | | | | | id/ki | | | | | | | | | | dney | | | | | | | | | | disor | | | | | | | | | | ders | | | | | | | | | | | | | | | | | | | | Fetal | | | | | | | | | | malfo | | | | | | | | | | rmati | | | | | | | | | | on | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Carba | Bipol | | Enzym | Antie | | Few | Ø | | | mazep | ar | | e | pilep | | ADR | Pregn | | | ine | depre | | induc | tic | | | ant | | | | ssion | | er | | | | = | | | Valpr | | | | | | | terat | | | oate | Epile | | Acute | | | | ogeni | | | | psy | | attac | | | | c | | | Lamot | | | k | | | | / | | | rigin | | | (Carb | | | | Spina | | | e | | | a/Val | | | | bifid | | | | | | pro) | | | | a | | | | | | | | | | (Valp | | | | | | Preve | | | | ro) | | | | | | ntion | | | | | | | | | | recur | | | | | | | | | | rence | | | | | | | | | | (Lamo | | | | | | | | | | ) | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Olanz | Atypi | | Antag | | | | | | | apine | cal | | onist | | | | | | | | antip | | D2 r | | | | | | | Rispe | sycho | | + | | | | | | | ridon | tic | | 5HT2A | | | | | | | e | | | r | | | | | | | | Schiz | | | | | | | | | Queti | ophre | | | | | | | | | apine | nia | | | | | | | | | | (2^nd | | | | | | | | | Aripi | ^ | | | | | | | | | prazo | gene) | | | | | | | | | le | | | | | | | | | | | Mania | | | | | | | | | \+ | | | | | | | | | | Fluox | Bipol | | | | | | | | | etine | ar | | | | | | | | | (SSRI | depre | | | | | | | | | ) | ssion | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Halop | Proph | | | | | | | | | erido | ylaxi | | | | | | | | | l | s | | | | | | | | | | mania | | | | | | | | | | c- | | | | | | | | | | depre | | | | | | | | | | ssion | | | | | | | | | | disor | | | | | | | | | | der | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Benzo | Anxie | Oral | GABA | Anxio | \>24h | Safe | ↑ | Bind | | diaze | ty | (lipo | A r | lytic | | | **CNS | adipo | | pine | | solub | selec | : | 60h | ↑ | depre | se | | (BZD) | Epile | le) | tive | ↓ | (Dia) | doses | ssant | t. | | | psy | | CL- | aggre | | = | ** | | | Long | (acut | IV | chann | ssive | 6-12h | drows | | Cross | | ½ : | e | | el | ness | | iness | Alcoh | BBB + | | | seizu | Recta | agoni | | \2y) | | bine | | | | | | | | | | | | | | | | | | | | Pheno | | | | | | | | | | barbi | | | | | | | | | | tal | | | | | | | | | | (Lumi | | | | | | | | | | nal/L | | | | | | | | | | umina | | | | | | | | | | letas | | | | | | | | | | ) | | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Pheny | Epile | Oral | Inhib | Antie | 30h | Dizzi | | Oxcar | | toin | psy | | it | pilep | | ness, | | = | | | (psyc | | NA+ | tic | | drows | | ↓drug | | Lamot | homot | | chann | | | iness | | metab | | rigin | or=pa | | el | Anxio | | , | | o | | e | rtial | | | lytic | | sedat | | enzym | | | + | | | | | °,con | | e | | Lacos | neuro | | | | | fus°, | | | | amide | pathi | | | | | ataxi | | | | | c | | | | | a | | | | Carba | Carba | | | | | | | | | mazep | / Ø | | | | | Nause | | | | ine | seizu | | | | | a, | | | | (Tegr | re | | | | | vomit | | | | etol) | Lamo) | | | | | ing, | | | | | | | | | | dry | | | | Oxcar | Bipol | | | | | mouth | | | | bazep | ar | | | | | , | | | | ine | (Carb | | | | | const | | | | | a/Oxc | | | | | ipat° | | | | | ar) | | | | | | | | | | | | | | | Leuko | | | | | Mania | | | | | penia | | | | | c-dep | | | | | , | | | | | ressi | | | | | throm | | | | | ve | | | | | bocyt | | | | | | | | | | openi | | | | | Neuro | | | | | a | | | | | pathi | | | | | | | | | | c | | | | | Rash, | | | | | pain | | | | | photo | | | | | | | | | | sensi | | | | | STADH | | | | | tivit | | | | | (synd | | | | | y | | | | | rome | | | | | | | | | | inapp | | | | | Menst | | | | | ropri | | | | | rual | | | | | ate | | | | | irreg | | | | | antid | | | | | ulari | | | | | iuret | | | | | ty | | | | | ic | | | | | | | | | | hormo | | | | | ↑ | | | | | ne | | | | | enzym | | | | | secre | | | | | e | | | | | tion) | | | | | trans | | | | | (Carb | | | | | amina | | | | | a) | | | | | se | | | | | | | | | | hepat | | | | | | | | | | itis | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Pheny | Epile | Oral | Barbi | | | Ataxi | Ø | Pheny | | toin | psy | | turat | | | a, | antic | toin | | | (psyc | | e | | | verti | oagul | = | | | homot | | | | | go, | ant | barbi | | | or=pa | | ↑ | | | gum | (warf | turat | | | rtial | | rate | | | hyper | arin) | e | | | / | | metab | | | troph | = ↑ | | | | tonic | | o | | | y, | metab | ! not | | | /clon | | drug | | | hirsu | o | to | | | ic) | | | | | tism | | use | | | | | | | | m. | Salic | If no | | | Bipol | | | | | megal | ylate | seizu | | | ar | | | | | oblas | s | re | | | (Carb | | | | | tic, | | ! | | | a) | | | | | anaem | Pheny | | | | | | | | | ia, | lbuta | Stop | | | Mania | | | | | fetus | zone | treat | | | c-dep | | | | | malfo | | ment | | | ressi | | | | | rmati | Valpr | 6m | | | ve | | | | | on, | oate | (if | | | | | | | | hyper | +/- | \>2y) | | | Neuro | | | | | sensi | effec | | | | pathi | | | | | tivit | ts | | | | c | | | | | y | | | | | pain | | | | | | (anti | | | | | | | | | | coagu | | | | | | | | | | lant) | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Ethos | Epile | | Inhib | | 60h | Nause | | | | uximi | psy | | it | | | a, | | | | de | (Ø | | CA 2+ | | | Anore | | | | | seizu | | chann | | | xia, | | | | | re) | | el | | | Letha | | | | | | | | | | rgy, | | | | | | | | | | Dizzi | | | | | | | | | | ness, | | | | | | | | | | Hyper | | | | | | | | | | sensi | | | | | | | | | | tivit | | | | | | | | | | y | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Valpr | Epile | | | Ø | 15 h | Nause | Ø | | | oate | psy | | | sedat | | a, | pregn | | | | (infa | | | ive | | hair | ant | | | Depak | ntile | | | | | loss, | = | | | ine | / | | | | | weigh | spina | | | | tonic | | | | | t | bifid | | | | -clon | | | | | gain, | a | | | | ic/my | | | | | fetal | !! | | | | oclon | | | | | malfo | malfo | | | | ic/ | | | | | rmati | rmat° | | | | parti | | | | | on | !! | | | | al/ | | | | | | | | | | Ø | | | | | | | | | | seizu | | | | | | | | | | re/id | | | | | | | | | | iopat | | | | | | | | | | hic) | | | | | | | | | | | | | | | | | | | | Bipol | | | | | | | | | | ar | | | | | | | | | | | | | | | | | | | | Migra | | | | | | | | | | ine | | | | | | | | | | proph | | | | | | | | | | ylaxi | | | | | | | | | | s | | | | | | | | +-------+-------+-------+-------+-------+-------+-------+-------+-------+ | Gabap | Epile | | | | 6h | | No | Prega | | entin | psy | | | | | | inter | balin | | \* | (part | | | | | | actio | = | | | ial | | | | | | n | analo | | Prega | seizu | | | | | | | gue | | balin | res) | | | | | | | + | | | |