Document Details

FineMossAgate3803

Uploaded by FineMossAgate3803

R. Long, MSN, RN, CPNP

Tags

respiratory drugs pharmacology pulmonary medicine health

Summary

This presentation covers various respiratory drugs, including their uses, forms, and special considerations. It details bronchodilators, anticholinergics, corticosteroids, leukotriene modifiers, mast cell stabilizers, methylxanthines, expectorants, antitussives, and mucolytics. It also mentions potential drug interactions and cautions.

Full Transcript

Respiratory Drugs NSG 170 R. LONG, MSN, RN, CPNP Used for bronchodilation Beta2- adrenergic Forms agonists  Inhalation (I) Examples  Systemic Albuterol (S,I)  Long-acting (L) Bitolterol (S,I)...

Respiratory Drugs NSG 170 R. LONG, MSN, RN, CPNP Used for bronchodilation Beta2- adrenergic Forms agonists  Inhalation (I) Examples  Systemic Albuterol (S,I)  Long-acting (L) Bitolterol (S,I)  Short-acting (S) Levalbuterol (S,I) Beta-adrenergic blockers Metaproterenol (S,I) decrease the bronchodilating Pirbuterol (S,I) effects of these drugs Often used with inhaled Terbutaline(S,Sy) Formoterol (L,I) corticosteroids Treat symptoms of COPD and Salmeterol (L,I) asthma Inhaled forms (neb or MDI) Anticholinergic Work locally s Bronchodilator Example: Relieve symptoms of COPD Ipratroprium bromide (Atrovent)… most commonly used and asthma Works in 15-20 minutes, lasts 3-5 hours Forms Corticosteroid  Inhaled s  Systemic-IV Examples: Most effective treatment and Beclomethasone (inhaled) prevention of acute asthma Prednisone (po) attacks Prednisolone (po- Special considerations liquid)  Peds-growth Hydrocortisone- sodium succinate  Elderly-osteoporosis Methylprednisolone  Diabetics- more carefully monitor -IV sodium blood glucose levels succinate  Passed to infant through breast milk Leukotriene Stop the effects of leukotrienes. modifiers Decreases: Examples:  airway constriction Montelukast (Singulair)  increased permeability of the vasculature Zafirlukast  increased secretions Zileuton  activation of inflammatory response. Used in place of steroids for control of mild to moderate asthma Mast cell Stabilize mast cell membrane Stabilizers preventing the release of Cromolyn sodium (Intal) inflammatory mediators nedocromil Prevention and long- term control of asthma symptoms Drug of choice for children and patients with exercise induced asthma Inhaled or oral.  Theophylline toxicity  Diet- High fat meals can increase risk Methylxanthine s  Must monitor blood levels. Therapeutic serum levels 10- Aminophylline (IV) 20mcg/mL Theophylline (oral)  Decrease airway reactivity and Caffeine bronchospasm  Bronchodilation * Caution… S/S of toxicity include GI,  Decreased inflammatory response nervous system,  Non-reversible airway disease and cardiac arrhythmias  Increase brains sensitivity to CO2  Reduce diaphragm fatigue  ACE (Asthma, chronic bronchitis, emphysema)  Used when there is increased production of respiratory secretions  Reduces thickness, adhesiveness, and Expectorants surface tension of mucus; making it Guaifenesin most easier to clear airway. Makes it easier commonly used to cough up secretions. (Mucinex) PO  Relieves symptoms of non- productive cough associated with  Bronchitis  Colds  Emphysema  Influenza  Sinusitis  Bronchial asthma  Minor bronchial irritation Treat serious non-productive cough Antitussives Drug interaction with *Dextromethorphan (Delsym, Robitussin, MAOI’s can lead to coma in Dayquil). PO-OTC. Codeine with other CNS depressants may increase Benzonatate (Tessalon) –RX only CNS depression (lethargy, Codeine-RX only drowsy, dizzy, respiratory Hydrocodone depression, coma, and death) bitartrate-Rx only Not advised to use with *most commonly used chronic conditions (asthma, COPD).  Break down sticky, thick secretions, thin it out and help it Mucolytics move easily from the lungs. Acetylcysteine (N-  Uses acetylcysteine)  Bronchitis Dornase Alpha (CF  Cystic fibrosis pts. Only)  COPD/asthma (Mucomyst and Pulmozyme..brand  Acetylcysteine also the antidote names). for Acetaminophen toxicity  Activated charcoal decreases the (Po, IV or nebulized) effectiveness  Not recommended for asthma patients due to risk of bronchospasm  Cause vasoconstriction which decreases inflammation and decreases capillary Decongestant permeability s  Topical decongestants have minimal Ephedrine (S, T) adverse reactions and act quickly Phenylephrine (Sudafed  Systemic decongestants PE) (S, T)  Cause jitteriness, trouble sleeping. Pseudoephedrine  combined with MAOIs may cause (Sudafed) (S,T) hypertensive crisis Oxymetazoline (Afrin nasal spray)  Combined with other sympathomimetic Naphazolone (T) drugs may cause greater CNS stimulation Tetrahydrozoline (T)  Pseudoephedrine sold behind the Xylometazoline (T) counter, due to it’s use in making (T- topical S-systemic- methamphetamines. po pills and liquid,  Phenyephrine no potential for misuse. nose gtts, nasal sprays). Epogen Colony Epogen increases RBC production by acting Stimulating like the hormone erythropoietin (in kidneys). Factors Used to treat anemia by helping the body Epogen, Procrit create more RBC’s (thus more Hgb). (RBC’s) (epoetin Hgb allows the body to carry O2 to the cells, alfa) (injection-SQ or thus increasing function of the organs. IV)) Decreases need for blood transfusions. Neupogen (WBC’s) Not for acute anemia/blood loss. Give 1-3 (filgrastim) x/week. (injection-SQ) Improves ability to walk, move, and do self care. Neupogen Bone marrow stimulant Helps the body make white blood cells (neutrophils). May give daily for 2 weeks. Side effects: bone pain, rash, headache.

Use Quizgecko on...
Browser
Browser