Rau's Chapter 6 Adrenergic Bronchodilators PDF
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Uploaded by CheapestPrudence4122
San Joaquin Valley College
2016
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Summary
This document is a chapter from a medical textbook discussing adrenergic bronchodilators. It covers clinical indications, short-acting and long-acting agents, and mechanisms of action. The chapter also includes information on the different routes of administration and adverse effects of these drugs.
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Rau’s Chapter 6 ADRENERGIC (SYMPATHOMIMETIC) BRONCHODILATORS Copyright © 2016, Elsevier Inc. All rights reserved. 2 CLINICAL INDICATIONS FOR ADRENERGIC BRONCHODILATORS Re...
Rau’s Chapter 6 ADRENERGIC (SYMPATHOMIMETIC) BRONCHODILATORS Copyright © 2016, Elsevier Inc. All rights reserved. 2 CLINICAL INDICATIONS FOR ADRENERGIC BRONCHODILATORS Relaxation of smooth airway muscle in the presence of reversible obstruction Asthma Acute, chronic, exercise-induced Bronchitis Emphysema Bronchiectasis Other obstructive airway diseases 3 INDICATION FOR SHORT- ACTING AGENTS (SABA) Acute reversible airflow obstruction Short-acting agents: a.k.a. “rescue” agents a.k.a. “relievers” Albuterol Levalbuterol Metaproterenol Copyright © 2016, Elsevier In. All rights reserved. 4 INDICATION FOR LONG- ACTING AGENTS (LABA) Maintenance bronchodilation, control of bronchospasm, and control of nocturnal symptoms a.k.a. “controllers” Salmeterol Formoterol Arformoterol Indacaterol Olodaterol Copyright © 2016, Elsevier Inc. All rights reserved. 5 INDICATIONS FOR RACEMIC EPINEPHRINE (RE) To control airway bleeding during endoscopy Strong a-adrenergic vasoconstricting effect to reduce airway swelling Postextubation stridor Epiglottitis Croup Bronchiolitis Coyright © 2016, Elsevier Inc. All rights reserved. 6 SPECIFIC ADRENERGIC AGENTS AND FORMULATIONS Ultrashort acting Duration
