Propylthiouracil (PTU) Medication Information
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Summary
This document provides information about the medication Propylthiouracil (PTU), highlighting its use in treating Graves' disease and related conditions. It also details potential side effects like liver dysfunction and agranulocytosis, crucial for monitoring patients. Important precautions and related conditions are discussed.
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**PROYLTHIOURACIL ( PTU)** \*used for graves disease (pre surgery) Monitor for hypo \* too much can cause hypo\* Liver function test is needed ( ALT/AST Does it work?? Yeah are the TSH and T4 levels good? **METHIMAZOLE** Hyperthyroid (graves disease) ( heat) A/E: hepatotoxic Agranulocytosis:...
**PROYLTHIOURACIL ( PTU)** \*used for graves disease (pre surgery) Monitor for hypo \* too much can cause hypo\* Liver function test is needed ( ALT/AST Does it work?? Yeah are the TSH and T4 levels good? **METHIMAZOLE** Hyperthyroid (graves disease) ( heat) A/E: hepatotoxic Agranulocytosis: s/s of infection CBC FEVER PALPIATION Monitor: TLC ( TSH , LFT CBC) TSH -- for the thyroid LFT- for the liver function CBC- for the infection **Lugol's solution (non-radioactive)** Thyroid storm Used to shrink thyroid before surgery \*Thyroid storm: high fever tachy agitation restless **I131- radioactive potassium iodine** Used to suppress thyroid activity Stay away ! Hypothyroidism : TSH stimulates the relase of T3 T4 Low T3 T4 HIGH TSH Cause: Hashimoto\'s : immune disorder most common Iodine plays. Key role in the synthesis of T3/T4 **LEVOTHYRONINE** Hypothyroidism: Take in the morning! Ask them when they take it DONOT TAKE FOR WEIGHTLOSS s/s for too much : Increase HR and Hot flashes BBW: use of thyroid hormone in treat of weight loss or obesity is contraindicated **HYDROCORTISON-** Addison's disease (life threating) inflammation Asthma allergies cancer copd \* take as ordered not when symptoms are present A/E HTN \*long term effects too much can turn into crushing\'s ( moon face and weight gain ) -\> ketoconazole **Steroid:** increase risk of infection \* suppresses immune system\* report low grade fever Teaching: maintain calcium report infection do not stop abruptly **COSYNTROPIN pg.681** \*Treats adrenocortical insufficient\* Resembles ACT\* and used to diagnosis cause of insufficiency Addison disease \* most common cause is stop corticosteroid without tappering **OCTEOTIDE-** acromegaly Too much growth hormone **Ketoconazole** -\>antifungal to decrease steroid levels in the body **Cushing disease:** causes elevated BP DM Meds. DM A1C: Glucose over the last 6-12 weeks \>6.5% indicates DM DM patients want \
