Biophysics for Dentistry (PHY113) Fall 2024/2025 Lecture 1 PDF

Class 2024/25 Biophysics for Dentistry ( PHY113 ) Fall 2024/2025 Lecture 1 Prof. Radwa Hassan Abou-Saleh [email protected]  PHY113--Lec 1 About The Course 2...

Class 2024/25 Biophysics for Dentistry ( PHY113 ) Fall 2024/2025 Lecture 1 Prof. Radwa Hassan Abou-Saleh [email protected]  PHY113--Lec 1 About The Course 2 Cr. Hrs. : 1CH= 1H Lecture/week 1CH= 2H Lab/ week SWL includes: Assessment is not 100% exam Course Grading Contact hours + Student time to Grade Distribution fulfil other activities Grade Distribution Example: Assessment measures Weight Presentations Participation Quizzes and Assignments 20% Projects Midterm exam 10% Assignments Lab book reports 15% Quizzes Practical Exam 15% Final Exam 40% Total 100% 3  PHY113--Lec 1 General Rules The lecture is 1 hour: 4  PHY113--Lec 1 About The Course Main Idea The course introduces the biophysics of cells with more details on the molecular structure of the plasma membrane and its role in controlling different transport mechanisms across the plasma membrane. 5  PHY113--Lec 1 About The Course Course content No. of weeks 1. Introduction 2. Cell Structure 3. Cell Dynamics 15 4. Transport across cell membrane. (Passive) weeks 5. Transport across cell membrane. (Active) 6. Membrane potential. 7. Nernest potential 8. Electrochemical driving force of ions across cell membrane 9. Action potential 10.Neurons and signal transmission 11.Mechanism of muscle contraction 12.Electromyogram 13.Electrocardiogram 6  PHY113--Lec 1 1- What is Biophysics? The field of science that collate basics of Physics, Math, Chemistry and Computer simulations to understand biological systems function and behaviour Use physical based methods and techniques and apply Laws of basic science together to understand and control biological systems 7  PHY113--Lec 1 2- Cells Types of cells Cells have the same internal chemical structure, same molecules, DNA with same 4 bases,…. BUT Cells have diverse range of functions and they broadly vary in size, appearance and chemical requirements to match their function Can you give example of cell shape that relates to its function ? 8  PHY113--Lec 1 2- Cells Types of cells 1. All living organisms are made up of cells. 2. Cells are the fundamental units of life; they are the smallest working unit that can perform functions 3. Solitary cells presents the simplest form of life. 4. Each living organism is a big colony of cells derived from pre-existing cells through cell growth and division. 5. Each cell in the colony has a specific function, and they are all organised through cell-to-cell communication 9  PHY113--Lec 1 2- Cells Types of cells Functional Examples White blood cell chases and catches a bacterium Fibroblast & Epithelial cells – David Rogers 1950 eg wound healing 10  PHY113--Lec 1 2- Cells Types of cells 11  PHY113--Lec 1 2- Cells Types of cells 12 PHY113--Lec 1 13