1st Prelim Exam PDF

1\. Free forms of fats are those that form ester bonds with carbon or alcohol a\. True b. False 2\. Phospholipids differ from triglycerides in structure by containing a phosphate group. a\. True b. False 3\. The bigger the lipoprotein the lesser protein fraction it has. a\. True b. False 4\. T...

1\. Free forms of fats are those that form ester bonds with carbon or alcohol a\. True b. False 2\. Phospholipids differ from triglycerides in structure by containing a phosphate group. a\. True b. False 3\. The bigger the lipoprotein the lesser protein fraction it has. a\. True b. False 4\. The bigger the lipoprotein the heavier it is. a\. True b. False 5\. In conditions where there is an elevated chylomicron and/or VLDL, triglyceride is elevated a\. True b. False 6\. Turbid serum is associated with the presence of chylomicrons. a\. True b. False 7\. Absence of apoprotein B100 is associated with the absence of LDL. a\. True b. False 8\. In conditions of hypercholesterolemia the HDL is expected to be low. a\. True b. False 9\. High levels of which lipoprotein class are associated with decrease risk of accelerated atherosclerosis? a\. Chylomicrons b. VLDL c. LDL d. HDL 10\. Which apoprotein is inversely related to risk or coronary heart disease? a\. apoprotein A1 b. apoprotein B100 c. apoprotein CII d. apoprotein E 11\. Which of the following mechanisms accounts for the elevated plasma level of beta-lipoproteins seen in familial hypercholesterolemia (formerly type III hyperlipoproteinemia)? a\. hyperinsulinemia b. ApoB-100 receptor defect b.Apo E deficiency d. Apo C-II activated lipase deficiency 12\. Select the lipoprotein fraction that carries the most of the endogenous triglycerides. a\. chylomicrons b. HDL c. LDL d. VLDL 13\. The protein composition of HDL is what percentage by weight? a\. less than 2% b. 25% c. 50% d. 90% 14\. The most cathodic lipoprotein which stays at the point of origin. a\. chylomicrons b. HDL c. LDL d. VLDL 15\. Recommended cut point for HDL cholesterol? a\. \/=60mg/dL c. 40-59 mg/dL 16\. Each lipoprotein fraction is composed of varying amounts of lipid and protein components. The beta-lipoprotein fraction consists primarily of which lipid? a\. fatty acid b. cholesterol c. phospholipid d. triglyceride 17\. What substance is the precursor to all steroid hormones? (use same choices in no. 16) ANSWER B 18\. The function of the major lipid components of the VLDL is to transport. a\. cholesterol from peripheral cells to the liver b\. cholesterol and phospholipids to peripheral cells c\. exogenous triglyceride d\. endogenous triglyceride 19\. Which of the following lipid results would be expected to be falsely elevated on a serum specimen from a non-fasting patient? a\. cholesterol b. HDL c. LDL d. triglyceride 20\. Transportation of 60%-75% of the plasma cholesterol is performed by. a\. chylomicrons b. HDL c. LDL d. VLDL 21\. Premature atherosclerosis can occur when which of the following becomes elevated? (use same choices in no. 20) ANSWER D 22\. In familial hypercholesterolemia, the hallmark finding is an elevation of a\. LDL b. chylomicrons c. HDL d. Apolipoprotein A1 23\. The function of the major lipid components of the very low-density lipoprotein is to transport. a\. cholesterol from peripheral cells to the liver b\. cholesterol and phospholipids to peripheral cells c\. exogenous triglyceride d\. endogenous triglyceride 24\. Which of the following lipid results would be expected to be falsely elevated on a serum specimen from a non-fasting patient? a\. cholesterol b. triglyceride c. HDL d. LDL 25\. Following ultracentrifugation of plasma, which fraction correlates with pre-beta lipoprotein? a\. VLDL b. LDL c. HDL d. chylomicron 26\. Protein with \>40% carbohydrates attached a\. metalloproteins b. glycoproteins c. mucoproteins 27\. The function of the protein binding or releasing H+ ions as needed. a\. cellular protein b. transporter c. buffer d. water distribution 28\. Catalysts that accelerate chemical reaction. a\. structural proteins b. antibodies c. enzymes 29\. All proteins are synthesized by the liver a\. True b. False 30\. Under normal condition proteins are excreted in urine in the form of a\. amino acids b. ammonia c. urea 31\. Reference range for total proteins a\. 6.2-7.5g/dL b. 6.3-8.0g/dL c. 6.5-8.3g/dL 32\. Which of the following conditions result to hyperproteinemia? a\. dehydration b. malnutrition c. urinary loss d. liver disorders 33\. Has the highest concentration of all plasma proteins. a\. pre-albumin b. albumin c. haptoglobin 34\. Indicator of nutritional status a\. pre-albumin b. albumin c. haptoglobin 35\. An acute-phase reactant which binds to basic drug a\. alpha-1-antitrypsin b. alpha-1-acid glycoprotein c. alpha-2-macroglobulin 36\. Binds with free hemoglobin. a\. alpha-2-globulin b. haptoglobin c. both 37\. Copper-containing protein. a\. C-reactive protein b. alpha-2-macroglobulin c. ceruloplasmin d. haptoglobin 38\. Predict risk of premature birth. a\. ceruloplasmin b. alpha-2-macroglobulin c. fibronectin d. immunoglobulins 39\. A test method for protein determination which is based on cupric ions complexing with peptide bonds in alkaline medium produce a purple-colored complex a\. dye binding b. Kjeldahl c. refractometry d. biuret 40\. The technique is based on the quantification of the nitrogen content of protein. (use same choices in no. 39) ANSWER B 41\. Buffer pH to carry out protein electrophoresis. a\. pH 8.0 b. pH 8.2 c. pH 8.4 d. pH 8.6 42\. Proteins in an electrophoresis has a \_\_\_\_ and travels towards the \_\_\_\_\_ a\. negative charge; anode b\. positive charge; anode c\. negative charge; cathode d\. positive charge; cathode 43\. The farthest travelling protein in an electrophoresis. a\. albumin b. alpha-1-globulins c. alpha-2-globulins d\. beta globulins e. gamma globulins 44\. Which is not used in dye binding method for albumin a\. bromcresol green b. Coomassie brilliant blue c. bromcresol purple d. none from the choices 45\. Bence Jones protein is associated with a\. glomerular dysfunction b. tubular dysfunction c. diabetes d\. multiple myeloma 46\. Microalbuminuria is associated with (use same choices in no. 45) ANSWER C 47\. Reference range for urine albumin. a\. \30mg/dL c. \50mg/dL 48\. Reference range for CSF proteins. a\. 15-25mg/dL b. 15-35mg/dL c. 15-45mg/dL 49\. Prostate specific antigen is specific to differentiating prostatic tumors. a\. True b. False 50\. Alpha feto protein normally has trace amounts in adults with levels \>20ng/mL a\. True b. False 51\. Tumor marker for colorectal a\. CEA b. CA 19-9 c. both 52\. Breast cancer marker a\. CA 15-3 b. CA 125 c. CA 19-9 For numbers 53-58, use the following choices: a\. monosaccharides b. disaccharides c. polysaccharide A 53. Galactose A 54. Fructose B 55. Maltose C 56. Starch B 57. Sucrose A 58. Glucose 59\. A fructose metabolism disorder which is characterized by a deficiency in the enzyme necessary for the formation of glucose from pyruvate a\. essential fructosuria b. hereditary fructose intolerance c\. fructose 1,6 diphosphate deficiency 60\. A tumor in the adrenal medulla causing excessive production of epinephrine and norepinephrine a\. Acromegaly b. Cushing's syndrome c. Pheochromocytoma 61\. Excessive desire to eat. a\. polyuria b. polydipsia c. polyphagia For numbers 62-67, use the following choices: a\. Type 1 DM b. Type II DM c. Gestational DM d. all of the choices A 62. Insulin dependent B 63. Maturity onset A 64. Seen in thin patients C 65. Seen in pregnant women A 66. Juvenile onset A 67. Ketosis prone 68\. If a fasting glucose was 90mg/dL, which of the following 2-hour post prandial glucose would most closely represent normal glucose metabolism? a.55mg/dL b.100mg/dL c.180mg/dL d.260mg/dL 69\. A healthy person with a blood glucose of 90mg/dL would have a simultaneously determined CSF glucose value of? a\. 30mg/dL b. 60mg/dL c. 80mg/dL d. 120mg/dL 70\. The conversion of glucose or other hexoses into lactate or pyruvate is called: a\. glycogenesis b. glycogenolysis c. gluconeogenesis d. glycolysis 71\. Monitoring long term glucose control in patients with adult onset diabetes can best be accomplished by measuring. a\. FBS b. GTT c. 2-hour post prandial d. HgbA1C For numbers 72-75, choose a\. if the first statement is true and second statement is false b\. if the first statement is false and second statement is true c\. if both statements are true d\. if both statements are false A 72. Insulin reduces blood glucose level. In diabetes mellitus there is overproduction of insulin that results to hyperglycemia. A 73. Glucose requires insulin for it to be distributed in the different cells of the body. Deficiency of insulin leads to hypoglycemia. D 74. Glucose is an inactive reducing substance. It is the only reducing sugar. C 75. Glucose is the only functional form of sugar in our body. It is the main source of energy our body needs.