Medication List-Module 2 PDF
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Summary
This document provides a list of medications, their uses, and pharmacological details. It covers topics such as pain relief and anti-inflammatory drugs, which are common in medical study materials.
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1. Acetaminophen o Use: Mild to moderate pain and fever; first-line analgesic. o Pharmacodynamics: Centrally acting weak COX-1 and COX-2 inhibitor; may activate serotonergic pathways. o Pharmacokinetics: Absorbed in the GI tract; metabolized in the liver; excreted in...
1. Acetaminophen o Use: Mild to moderate pain and fever; first-line analgesic. o Pharmacodynamics: Centrally acting weak COX-1 and COX-2 inhibitor; may activate serotonergic pathways. o Pharmacokinetics: Absorbed in the GI tract; metabolized in the liver; excreted in urine. Half-life: ~2–3 hours. o Details: Maximum dose: 4 grams/day. Risk of liver damage with overdose. Suitable during pregnancy if non-pharmacologic therapy fails. 2. Ibuprofen o Use: NSAID for pain, inflammation, and fever. o Pharmacodynamics: Inhibits COX-1 and COX-2, reducing prostaglandin synthesis. o Pharmacokinetics: Well absorbed orally; metabolized in the liver; excreted in urine. Half-life: ~2 hours. o Details: Contraindicated in late pregnancy. Associated with GI side effects. 3. Aspirin o Use: NSAID for pain, fever, inflammation, and as an antiplatelet agent. o Pharmacodynamics: Irreversibly inhibits COX-1 and COX-2, decreasing prostaglandin and thromboxane synthesis. o Pharmacokinetics: Rapidly absorbed in the stomach and small intestine; metabolized to salicylic acid; excreted in urine. o Details: Avoid in children
