Medication List-Module 2 PDF
Document Details
Uploaded by BonnyAntigorite9581
Tags
Summary
This document is a list of medications, detailing their uses, pharmacodynamics, pharmacokinetics, and key details. It appears to be part of a module, possibly in a pharmacology course, covering various drugs and their applications.
Full Transcript
1. **Acetaminophen** - **Use**: Mild to moderate pain and fever; first-line analgesic. - **Pharmacodynamics**: Centrally acting weak COX-1 and COX-2 inhibitor; may activate serotonergic pathways. - **Pharmacokinetics**: Absorbed in the GI tract; metabolized in t...
1. **Acetaminophen** - **Use**: Mild to moderate pain and fever; first-line analgesic. - **Pharmacodynamics**: Centrally acting weak COX-1 and COX-2 inhibitor; may activate serotonergic pathways. - **Pharmacokinetics**: Absorbed in the GI tract; metabolized in the liver; excreted in urine. Half-life: \~2--3 hours. - **Details**: Maximum dose: 4 grams/day. Risk of liver damage with overdose. Suitable during pregnancy if non-pharmacologic therapy fails. 2. **Ibuprofen** - **Use**: NSAID for pain, inflammation, and fever. - **Pharmacodynamics**: Inhibits COX-1 and COX-2, reducing prostaglandin synthesis. - **Pharmacokinetics**: Well absorbed orally; metabolized in the liver; excreted in urine. Half-life: \~2 hours. - **Details**: Contraindicated in late pregnancy. Associated with GI side effects. 3. **Aspirin** - **Use**: NSAID for pain, fever, inflammation, and as an antiplatelet agent. - **Pharmacodynamics**: Irreversibly inhibits COX-1 and COX-2, decreasing prostaglandin and thromboxane synthesis. - **Pharmacokinetics**: Rapidly absorbed in the stomach and small intestine; metabolized to salicylic acid; excreted in urine. - **Details**: Avoid in children \
