MED1003 Molecules, Cells, and Genes Seminar PDF

MED1003 Molecules, Cells and Genes by Siu Wai (Phyllis) TSANG, PhD TUNG WAH COLLEGE email: [email protected] Office#: 3190-6713 Prepared by SWT 2024 email: [email protected] 1 Self-test question 1 What is the base sequence of the DNA strand that wo...

MED1003 Molecules, Cells and Genes by Siu Wai (Phyllis) TSANG, PhD TUNG WAH COLLEGE email: [email protected] Office#: 3190-6713 Prepared by SWT 2024 email: [email protected] 1 Self-test question 1 What is the base sequence of the DNA strand that would be complementary to the following single-stranded DNA molecule? 5'─GGATCTGATCCAGTCA─3' Answer: Prepared by SWT 2024 email: [email protected] 2 Self-test question 2 If a double stranded DNA has 20% of cytosine, calculate the % of adenine in such strand. Answer: Prepared by SWT 2024 email: [email protected] 3 Self-test question 3 If a double stranded DNA has 38% of adenine, calculate the % of cytosine in such strand. Answer: Prepared by SWT 2024 email: [email protected] 4 DNA sequence The order of the DNA bases (i.e., DNA sequence) determines the genetic code (i.e., gene) Prepared by SWT 2024 email: [email protected] 5 Activity GenBank (NIH genetic sequence database) https://www.ncbi.nlm.nih.gov/genbank/ Search for the gene encodes insulin in humans (Homo sapiens) Prepared by SWT 2024 email: [email protected] 6 Activity Prepared by SWT 2024 email: [email protected] 7 Cells and organelles by Siu Wai (Phyllis) TSANG, PhD TUNG WAH COLLEGE email: [email protected] Office#: 3190-6713 Prepared by SWT 2024 email: [email protected] 8 Study of cells (Cell biology) The cell is the basic structural and functional unit of life Cells provide structure and function for all living things, from microorganisms to humans The study of the cell structure and functions → cell biology Based on cellular structures, cells are of two classic categories: eukaryotic and prokaryotic cells Three domains Prepared by SWT 2024 email: [email protected] 9 Prokaryotes vs eukaryotes Eukaryotic cells have a true, membrane-bounded nucleus Prokaryotic cells are non-nucleated cells, i.e., have no true nucleus da338.webp?image_crop_resized=1280x720 ssl.wistia.com/deliveries/3854dd6eae570ac870fd63d5273 https://embed- 真核細胞 原核細胞 Prepared by SWT 2024 email: [email protected] 10 Prokaryotes Prokaryotes are mostly single-celled (i.e., unicellular 單細胞) microorganisms archaea and bacteria Cell size ranges from 1 to 5 µm in diameter Hereditary material can either be DNA or RNA Genetic material is freely suspended in the region called nucleoid Three common shapes: spheres, rods & spirals http://baels.weebly.com/uploads/3/0/4/1/30415598/3078032_orig.png Prepared by SWT 2024 email: [email protected] 11 Eukaryotes https://labster-image-manager.s3.amazonaws.com/v2/NAP/2496ca78- fcf8-4143-b537-b6bd3509601c/NAP_DNALocation.en.x1024.png Eukaryotes are characterized by a true nucleus plants, fungi, protozoa and animals Cell size ranges between 10−100 µm in diameter Hereditary material DNA is packed in the nucleus https://miro.medium.com/max/2048/0*25ZMg14TARvhv4Bg.png Prepared by SWT 2024 email: [email protected] 12 Prepared by SWT 2024 email: [email protected] 13  Prepared by SWT 2024 email: [email protected] 14 Prokaryotes vs eukaryotes ene_Intron_Exon_nb.svg/800px-Gene_Intron_Exon_nb.svg.png https://upload.wikimedia.org/wikipedia/commons/thumb/2/27/G https://ib.bioninja.com.au/_Media/pro-vs-eukaryote_med.jpeg Prepared by SWT 2024 email: [email protected] 15 Prepared by SWT 2024 email: [email protected] 16 https://haygot.s3.amazonaws.com/questions/1170402_963466_ans_7a5794475a36497b87747cd3a92eb21a.jpg Prepared by SWT 2024 email: [email protected] 17 ~ The end ~ Thank you ! Prepared by SWT 2024 email: [email protected] 18