Mark Klimek Notes PDF
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Mark Klimek
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These lecture notes by Mark Klimek cover various medical topics, including Acid-Base Balance, Ventilators, and Alcohol. The notes include definitions, values, rules, causes, and treatment options for the topics mentioned.
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Key: - bold (titles) - red (important letters or mnemonics) - yellow (highlighted info) Lecture 1 Acid Base Balance - Convert lab values to words & interpret - Rule of the B’s - If the pH & the Bicarbonate are Both in the same...
Key: - bold (titles) - red (important letters or mnemonics) - yellow (highlighted info) Lecture 1 Acid Base Balance - Convert lab values to words & interpret - Rule of the B’s - If the pH & the Bicarbonate are Both in the same direction then it’s metaBolic — otherwise it’s respiratory (since it has no B in it) - Values - pH = 7.35-7.45 - HCO3 = 22-26 - CO2 = 35-45 - Principles - As the pH goes, so goes my patient — except for K+ - pH goes up — alkalotic — hyper & irritable - Pt needs suctioning cause they could seize & aspirate - pH goes down — acidosis — low & slow - Pt needs Ambu bag cause they could go into respiratory arrest - MAC Kussmaul — only acid base balance to cause Metabolic ACidosis with Kussmaul respirations - Example: Pt has respiratory acidosis. SATA - +1 reflexes !! - Diarrhea – high X - Adynamic ileus !! (Without movement) - Spasm – high X - Urinary retention !! - Paroxysmal atrial tachycardia – high X - Second degree Mobitz Type II Heart Block !! - Hypokalemia – would be hyperkalemia due to exclusion of K+ - Causes - First ask “is it LUNG?” → respiratory problem - Second ask “are they over ventilating or under ventilating?” - OVERventilating = alkalosis (OVER 7.45) - UNDERventilating = acidosis (UNDER 7.35) - Ventilation is about gas exchange not respiratory rate — not about RR, it’s about the SAO2 - Important to look at SAO2 instead cause RR could end up compensating & lead you to wrong answer - If it is not LUNG → metabolic problem - If patient has prolonged gastric vomiting or suctioning (losing acid)— pick alkalosis - Everything else that isn't lung — pick acidosis Ventilators - Alarms - High pressure alarms — always triggered by increased resistance to air flow - Machine is having to push too hard to get the air into the lungs - Caused by obstructions! - Kinks = unkink it - Water condensing in the tube = empty it - Mucus secretions in airway = change position, turn, cough, deep breathe, & then suction - More suction = more secretions problems - Only suction when necessary — when they cannot mobilize secretions after they turn, cough, & deep breathe - Low pressure alarms — always triggered by decreased resistance - Machine works too little/too easy to get air into lungs - Caused by disconnections! - Main tubing = reconnect - O2 sensor tubing (measures FIO2; oxygen delivered) = plug it back in - Only reconnect unless tube is on floor — bag pt & call RT - Settings - Overventilated = setting too high = respiratory alkalosis — panting - Underventilated = setting too low = respiratory acidosis — retaining CO2 Lecture 2 Alcohol - Number one problem in all abusive situations = Denial - Abusers have an infinite capacity to deny - Deny in order to continue the behavior — allows them to keep doing it without having to answer for it/deny that they have a problem - Why is this a problem? → can’t treat someone who denies they have problem - Definition — refusal to accept the reality of a problem - How to treat? - Confront them with what they do & say - Confrontation attacks problem while aggression attacks person - When dealing with psychodynamic issues with staff, use the “I” statements not “You” - Denial is okay in loss & grief situations — support not confront! - Stages of grief — DABDA - Number two problem that abusers have = dependency/codependency - Dependency — abuser asks partner to do things for them - Codependency — partner gets positive self esteem from doing things for abuser - How to treat? Set limits & enforce them - Teach partner to say no - Work on self esteem of codependent person - Because when they say no, the abuser will attack their self esteem Manipulation - When abuser gets partner to do things that are not in the best interest of partner — dangerous & harmful - Like dependency — getting partner to do things - Manipulation = dangerous & harmful - Dependency = not inherently dangerous & harmful - How to treat? Set limits & enforce them Wernicke (Korsakoff) Syndrome - Go together - Wernicke — encephalopathy - Korsakoff — psychosis - Psychosis induced by Vit B1, thiamine deficiency (lose touch with reality d/t deficiency) - Primary S/Sx - Amnesia (memory loss) - Confabulation (making up stories) - They believe their lies — just as real as reality - How to deal with pt with this: - Do not present reality because they can’t learn it - Do not get in fight about what is real — pointless - Redirect instead to something that they can do - Characteristics: - Preventable —> take Vit B1 (needed to metabolize alcohol — if not it will accumulate & destroy brain cells) - Arrestable (stop from getting worse) —> take Vit B1 - Irreversible (70%) Antabuse & Revia (Disulfiram) - Aversion therapy — develop a gut hatred for habit - When you take in the alcohol, you will get super sick - Doesn’t work as well as they say it does — just in theory - Onset & duration = 2 weeks - Patient teaching: - Teach to avoid all forms of alcohol — to avoid N/V, death - Items that contain alcohol: mouth wash, cologne, perfume, aftershave, any OTC that ends in elixir, insect repellant, alcohol based hand sanitizer, uncooked icing since it has vanilla extract - Do not pick Red Wine vinaigrette! — it does not have alcohol! Overdose & Withdrawal - Every abused drug is either an Upper or Downer - Laxatives are abused by the elderly - Upper - Types: - Caffeine - Cocaine - PCP/LSD (psychedelics/hallucinogens) - Methamphetamines - Adderall - Signs & Symptoms: - Things go UP! - Euphoria, tachycardia, restlessness, irritability, hyper reflexes (3+, 4+) increased bowels (borborygmi), diarrhea, spastic, seizures - Priority: check reflexes - Anticipate suctioning d/t seizures - Downer - If it’s not an upper, then it’s a downer - Signs & Symptoms: - Things go DOWN! - Lethargic, respiratory depression/arrest, constipated - Priority: check respirations - Anticipate intubation/ventilation d/t respiratory arrest - After knowing that the drug is an Upper or Downer, ask yourself if it’s an Overdose or Withdrawal - Too little upper — makes everything go down - Too little downer — makes everything go up - Upper overdose = downer withdrawal - Biggest risk — seizures - Downer overdose = upper withdrawal - Biggest risk — respiratory arrest Drug Abuse in Newborn - Always assume intoxication not withdrawal at birth - After 24 hours or more after birth — withdrawal Alcohol Withdrawal Syndrome vs Delirium Tremens - Not the same - Every alcoholic goes through alcoholic withdrawal approx. 24 hrs after they stop drinking - Less than 20% alcoholics in alcoholic withdrawal syndrome progress to delirium tremens — about 72 hrs after they stop drinking - AWS — not life threatening to self to others - Regular diet - Semi private; anywhere - Up ad lib (free to move around anywhere) - No restraints - DT — can kill you; life threatening to self or others - NPO (seizures) or clear liquids - Private; near nursing station - Restricted bed rest (no bathroom privileges; not free to move around) - Restraints (vest or 2 point (extremities; opposite arm & leg) lock leathers) - Switch extremities every 2 hours - Both get anti-HTN med, tranquilizer, multivitamin containing Vit B1 - Anti-HTN since everything is going up due to downer withdrawal - Tranquilizer since they’re up - Multivitamin to prevent Wernicke Aminoglycosides - Dangerous; powerful class of abx — use it when nothing else works - Common tested drugs: - Top 5 - Psychiatric, Insulin, Anticoagulant, Digitalis, Aminoglycosides - Others - Steroids, Beta blockers, CCB, Pain, OB meds - Aminoglycosides = A Mean Old Mycin - Abx used to treat serious, resistant, life-threatening, gram negative infections - Treat a mean old infection with mean old mycin - Yes — TB, septic peritonitis, fulminating pyelonephritis, septic shock, infection from third degree wound covering >80% of body - No — sinusitis, otitis media, bladder infections, viral pharyngitis, strep throat - All aminoglycosides end in Mycin - Not all drugs ending in Mycin are aminoglycosides - Azithromycin, Erythromycin, Clarithromycin have THRO in middle = THRO them off the list! - Toxic effects: - Mycin — sounds like mice (think ears of Mickey Mouse) = Ototoxic - Monitor hearing, balance, tinnitus - Human ears are shaped like kidneys = Nephrotoxic - Monitor Creatinine (best indicator of kidney function) - If they ask 24 hr creatinine or serum creatinine, 24 hr is better - Number 8 drawn inside the ear reminds you of: - Toxic to CN8 (ear nerve) - Administer every 8 hours - Route: IM or IV - Do not give PO — they are not absorbed - Except in: - Hepatic encephalopathy (hepatic coma) when ammonia gets too high — kills E. coli (#1 producer of ammonia) in the gut & decreases ammonia level - Pre-op bowel surgery to sterilize the bowel - Will not have ototoxicity or nephrotoxicity because they are not absorbed - Oral Mycin = sterilizes bowel - Neomycin & Kanamycin - ”Who can sterilize my bowel?” — Neo Kan! Peak & Trough - Trough — when drug is at its lowest - Peak — when drug is at its highest - TAP levels — trough, administer, peak - Trough before drug admin - Peak after drug admin - Drawn due to narrow therapeutic window — small difference in what works & what kills (such as digoxin) - Mean Old Mycins have TAPs drawn on them due to their narrow therapeutic windows — not the only drugs that have TAPs drawn but they a major class in which you draw TAPs - When to draw Trough & Peak: - Don’t have to know what the drug is — not medication dependent but route dependent - Troughs — always drawn 30 mins before next dose - Peaks — depend on route - SubL — 5-10 min after drug dissolves - IV — 15-30 mins after drug is finished (start clock when bag is empty) - IM — 30-60 mins - SubQ — depends on insulin (diabetes lecture) - PO — not necessary, not tested (forget about it) - If there are two right answers with peak questions, choose the answer with the highest time without going over time range Lecture 3 Calcium Channel Blockers - CCB are like Valium for the heart — calm heart down - CCBs are negative inotropic, chronotropic, dromotropic = fancy words to say that they relax & calm heart — cardiac depressant - When would you want to relax, slow, calm heart down? - To treat A, AA, AAA - Antihypertensive — relax heart & blood vessels = BP goes down - AntiAnginal — relaxes heart & uses less oxygen; decreases oxygen demand - Angina will speed up heart & cause issues - AntiAtrialArrhythmia — treats atrial arrhythmias - Also treats SVT since Supraventricular means above the ventricles & atrium is above - Side effects: H&H — headache & hypotension - Headache = d/t vasodilation in brain & gives you a migraine (HA pertains to a lot of situations) - Hypotension = relaxes heart & blood vessels - Names: ends in “dipine” NOT “pine” — - “Dipine in the calcium channel’ - Others that are in this category: - Verapamil - Cardizem — can be given continuous IV drip - Assess BP & hold if SBP where? In water seal chamber - Intermittent = good (document it) - Continuous = bad (there is a leak; find it & tape it until it stops leaking) - Bubbling —> where? In suction control chamber - Intermittent = bad (suction is too low; go to wall & increase until continuous) - Continuous = good (document it) - If something is sealed — you should NOT have continuous bubbling cause that would mean it’s leaking (intermittent is good) Analogies - A straight catheter is to a Foley catheter as a thoracentesis is to a chest tube - The one staying in has a higher risk of infection Rules for clamping tubes - Do not clamp for more than 15 secs without order - Use rubber tipped double clamps (cover teeth of clamp with rubber so it won’t puncture tubing) Congenital Heart Defects - Every defect is either trouble or no trouble — nothing in between - Memorize: TRouBLe (lowercase vowels) - If a congenital heart defect is TRouBLe: - Need surgery now/soon to live - Has slowed/delayed growth & development (failure to thrive) - Has a shortened life expectancy - Parents will experience a lot of grief, financial & emotional stress - Pt is likely to be discharged home on a cardiac monitor - After birth, pt will be in hospital for weeks - Pediatrician or pediatric nurse will likely refer pt to a pediatric cardiologist - TRouBLe —> shunts blood Right to Left - TRouBLe —> Blue (cyanotic) - All TRouBLe starts with letter T - Tetralogy of Fallot - Truncus arteriosus - Transposition of the great vessels - Tricuspid atresia - Totally anomalous of pulmonary vasculature (TAPV) - Except, Left ventricular hypoplastic syndrome - No TRouBLe congenital heart defects - Ventricular septal defect (VSD) - Patent ductus arteriosus (PDA) - Patent foramen ovale - Atrial septal defect - Pulmonic stenosis - All children with a congenital heart defect (whether TRouBLe or not TRouBLe) will have murmur & echocardiogram done to find out cause of murmur - 4 defects of Tetralogy of Fallot - VarieD PictureS Of A RancH - VD = ventricular defect - PS = pulmonary stenosis - OA = overriding aorta - RH = right hypertrophy Infectious Disease & Transmission-Based Precautions - 4 types: standard/universal, contact, droplet, airborne - Contact precautions: - Types: - Anything enteric (can be caught by intestine; fecal/oral) - C diff, Hep A, E. coli, cholera, dysentery - Staph - RSV (droplets fall onto object then pt touches object or put it in mouth — kids get it from touching things that other kids touched) - Herpes - PPE: - Private room is preferred - Can be placed in same room as long as you cohort — same disease based on culture & NOT symptoms - Hand washing, Gown, Gloves - Disposable supplies (gloves, paper plates, plastic utensils) - Dedicated equipment (stethoscope, BP cuff) & toys stay in room - Droplet precautions: - For bugs traveling 3 feet on large particles due to coughing or sneezing - Types: - Meningitis - H. Influenzae b - Causes epiglottitis (nothing in throat) - PPE: - Private room is preferred - Can be in same room if cohort based on culture - Meningitis culture from spinal taps/lumbar punctures - Hand washing, Mask, Gloves - Pt wears mask when leaving room - Disposable supply - Dedicated equipment - Airborne precautions: - Types — “MTV” - MMR (measles, mumps, rubella) - TB (spread by droplet but airborne precaution since particles stays in air) - Varicella (chickenpox) - PPE: - Private room required unless cohorting - Hand washing, Mask, Gloves - Pt wears mask when leaving room - Special filtered mask for TB - Keep door closed - Disposable supply (not essential) - Dedicated equipment (not essential) - Negative airflow PPE - Order to put it on — reverse alphabetical for G’s but mask comes second - Gown - Mask - Goggles/Face Shield - Gloves - Order to take it off — in alphabetical order - Gloves - Goggles/Face Shield - Gown - Mask Math Problems - Dosage calculation - IV drip rates = Volume x Drop factor/Time - Micro/Mini drip = 60 drops per mL - Macro drip = 10 drops per mL - Pediatric dose (2.2 lbs = 1 kg) - Always be dividing by 2.2 - Leading zeros as long as they maintain place — NO trailing zeros - Boards will tell you what to round to - You do not have to put units in answer Lecture 4 Crutches, Canes, Walkers - Measuring Crutches - Important for risk reduction & avoiding nerve problems - Length of crutch — 2-3 finger widths below anterior axillary fold to a point & lateral to slightly in front of foot - Wrong — landmarks on foot or say axilla! - Hand Grip measurement - Can be adjusted up & down - When hand grips are properly placed, the angle of elbow flexion will be about 30 degrees - How to Teach Crutch Gaits - 2 point gait — move a crutch & opposite foot together followed by the other crutch & other foot together — always moving 2 things 2gether 2,2,2… - 3 point gait — moving two crutches & bad leg together followed by good leg — 3,1,3,1… - 4 point gait — move everything separately - Move crutch, opposite leg, other crutch, other leg, etc. — very slow but stable - Swing through — for non-weight bearing such as amputation — bad leg never touches down - Can move really fast - When to Use Gaits - Even for even, Odd for odd - Even numbered gaits when the weakness is evenly distributed — even number of legs messed up - 2 point for mild problem - Mild bilateral weaknesses - 4 point for severe problem - Severe bilateral weaknesses - Odd numbered gait when affected leg is odd - 3 point - If pt cannot bear weight or have amputation - Swing through - Going Up & Down Stairs with Crutches - Up with the Good, Down with the Bad - Up stairs — lead with good leg - Down stairs — lead with bad leg - Crutches always move with bad leg - Canes - Hold cane on strong side - Advance with bad leg for wide base of support which keeps you upright - Walker - Pick them up, Set them down, Walk to them - Don’t tie belongings to front of walker, tie on side so it won’t tip over - Wheels & tennis balls can create problems Psych - Non-psychotic vs psychosis - First decide if pt is non-psychotic or psychotic - Matters since it’ll determine treatment, goals, prognosis, medications, length of stay, legalities, etc. - Non-psychotic person - Has insight & reality based - They know they have a problem, they know what the problem is, they know how it’s messing up their life & what they sense is what you can sense - Good therapeutic communication - Tell me more about… - That must be very difficult.. - How are you feeling… - Reflection, clarification, amplification, restatement, etc. - Psychotic person - Has no insight & not reality based - They don’t know they’re sick & think everyone else has the problem & not them — blames everyone but themselves - They may be able to state the disease but doesn’t mean they have the insight - Delusions, hallucinations, & illusions — psychotic symptoms - Delusions — false, fixed belief or idea or thought - Fixed — they don’t change it - No sensory component — all in head - 3 types of delusions: - Paranoid: people are out to harm you - Grandiose: you are superior (I am the world’s smartest man; I am the President) - Somatic: body part (I have X-ray vision; there are worms inside my arm; my body is hollow) - Hallucinations — false, fixed sensory experience - Auditory (1st most common) - Hearing things that aren’t there - Voices telling you to harm yourself - Visual (2nd most common) - Seeing things that aren’t there - Tactile (3rd most common) - Feeling things that aren’t there - Gustatory - Tasting things that aren’t there - Olfactory - Smelling things that aren’t there - Illusions — misinterpretation of reality/what’s going on - Sensory experience Differentiation between hallucinations & illusions - Illusion — there is a referent in reality - Something in reality to which a person refers when they say something — something's there but they just misinterpret what it is - Hallucination — there is absolutely nothing there How to Deal with Psychotic Patients - First ask what type of psychosis does pt have - 3 types of psychosis: - Functional psychotic - Can function in everyday life (have a job, married, take care of themselves, pay taxes, etc.) - No brain damage but chemicals are out of balance — have potential to learn reality - Role as nurse — teach reality - 4 step process: - Step 1: Acknowledge feeling - Usually word “feel” is in answer/or word specifies feeling - I see you’re upset…that must be distressing…that’s so sad…tell me more about what you’re feeling… - Step 2: Present reality - You can tell them what reality is or compare their views with yours - I know…is real to you..but I don’t…I understand those voices are real to you but I don’t hear them….I am a nurse, this is a hospital and this is your breakfast - Step 3: Set limits - That topic is off limits in our conversation…When we talk together, we’re not going to talk about that…Stop talking about… - Step 4: Enforce limits - Ending the conversation — not taking away privilege like a punishment - Good because you won’t accomplish anything & by continuing you’re just reinforcing non-reality - I see you’re too ill to stay reality based so our conversation is over… - 4 diseases that make up 90% of this category: - “Skeezo, Skeezo, Major, Manics” - Schizophrenia, Schizoaffective disorder, Major depression (not depression), Mania - Bipolars are only psychotic in mania phase - Example: ”I can see that would be frightening. They are not plotting. We are not going to talk about that. I can see you are too ill. We are ending the conversation.” - Psychosis of dementia - Actual damage to brain - Due to Alzheimer’s, stroke, organic brain syndrome - Anything that says Senile/Dementia falls in this category - Cannot learn reality — do not present it - Will only frustrate & anger them & discourage you - Presenting reality is not the same as reality orientation (person, place, time) — appropriate with dementia - 2 steps: - Step 1: Acknowledge feeling - Step 2: Redirect them - Channel them from something they can’t do to something they can do - Example: “I understand you seem to be scared. Let’s go somewhere you feel safe” - Psychotic Delirium - Temporary, sudden, dramatic, episodic, secondary loss of reality - Usually due to some chemical imbalance in body - Crazy for the short term because of something else causing them to be crazy — due to drugs/medications (withdrawal, overdose, post op, UTI, thyroid storm, adrenal crisis, electrolytes) - Manage by treating underlying cause - 2 steps: - Step 1: Acknowledge feeling - Step 2: Reassure them of safety & temporariness of condition - Do not present reality since they lost touch with reality — won’t do anything - Example: “That must be scary. But you are safe. Your fear will go away when you get better.” How to Approach Questions - 1st step: Is pt non-psychotic or psychotic? - 2nd step: If non-psychotic → good therapeutic communication - 3rd step: If psychotic → figure out which of the 3 categories - All three start with acknowledge feeling - Next step always begins with Re — Reality, Redirect, Reassure Psychotic Symptoms - Loose associations — thoughts are wrapped too tight/all over the map - Flight of Ideas — go from thought to thought - Say phrases that are coherent but phrases aren’t connected/coherent together - Word Salad - Sicker than flight of ideas - Can’t make phrase that is coherent — just babble random words - Neologisms — making up imaginary words - Narrowed self-concept — when a psychotic refuses to leave their room or change their clothes - Functional psychotic - Self-concept — how you define who you are - They define themselves very narrow — based on two things: where they are & what they’re wearing - Reason for doing so — they don’t know who they are unless they are wearing those things in that room — terrifies them to change & leave - Don’t make them do it — they will cease to know who they are & they will panic = someone will get hurt - “I see you are uncomfortable/upset. You do not have to leave your room or change your clothes until you are ready.” - Idea of reference – You think everyone is talking about you Lecture 5 Diabetes Mellitus — error of glucose metabolism (glucose is body’s primary fuel source — w/o it, cells die) - Lack of insulin - Insulin resistance Diabetes Insipidus — not a type of DM - Polyuria & polydipsia leading to dehydration d/t low ADH - Just the fluid part of DM — high UOP - Opposite of DI — SIADH DM has polyuria & polydipsia — DI has polyuria & polydipsia - SIADH is the opposite of those conditions so… - Low UOP (oliguria) & not thirsty (retaining water) Amount of urine & specific gravity relationship — inverse - Less urine out = higher specific gravity - SIADH - More urine out = lower specific gravity - DM, DI Fluid volume deficit = DM, DI Fluid volume excess = SIADH Diabetes - Type I — Insulin dependent, Ketosis prone - Type II — Non-insulin dependent, Non-ketosis prone - S/S: Polyuria (pee a lot), polydipsia (drink a lot), polyphagia (eat a lot/inc swallowing) - Treatment: - Type I — don’t treat, they will DIE - Diet (least important) - Insulin (most important) - Exercise - Type II — don’t treat, they are DOA - Diet (most important) - Oral hypoglycemic (pill) - Activity - Least important for type I = most important for type II - Diet for DM2 - Calorie restriction — primary dietary modification - They need 6 small feedings a day - Smaller more frequent meals keeps blood sugar more stable - Best – Restrict calories or divide meals? - Restrict calories is best bc eating 6 meals doesn’t limit calories with each meal Insulin — acts to lower blood glucose - 4 types: - R - Regular - Onset: 1 hr - Peak: 2 hrs - Duration: 4 hrs - Clear, solution — can be IV drip - HESI: Intermediate acting insulin - FDA: Rapid short acting insulin - R: regular, rapid, run IV - Pattern: 1-2-4 — remember peak! (2) - N - NPH - Onset: 6 hrs - Peak: 8-10 hrs - Duration: 12 hrs - Intermediate acting insulin - Cloudy, suspension = precipitates (particles fall to bottom over time) — cannot be given IV drip - N: NPH, not so fast (intermediate), not in bag (no IV) - Pattern: 6-8-10-12 — remember peak! (8-10) - Lispro/Humalog - Fast acting insulin - Give as pt begins to eat — with meal not AC (before meals) - Onset: 15 mins - Peak: 30 mins - Duration: 3 hrs - Pattern: 15-30-3 - Glargine/Lantus - Long acting insulin - No peak — slowly absorbed - Little to no risk for hypoglycemia - Only one you can safely give at bedtime - Duration: 12-24 hrs - Always check insulin expiration dates! - What action invalidates the manufacturer's expiration date? - Opening the package/vial - Expiration date is only good if still closed - Once the package is open, manufacturer's expiration date is irrelevant — new expiration date is 30 days after that - Make sure to write: - ”OPEN” and the date when it was opened or ”EXP” and expiration date - Refrigeration is optional in the hospital but you should teach patients to refrigerate insulin at home - Unopened vials of insulin should be refrigerated in the hospital - When vial is opened: you must write new expiration date & it does not need to be refrigerated any longer — in the hospital - Exercise potentiates (does the same thing as) insulin - Exercise is like having another shot of insulin - More exercise = more shots of insulin = need less insulin - Less exercise = need more insulin Sick days - When a diabetic gets sick = glucose will go up (due to stress of illness) - Have to take insulin even if they aren’t eating - Take sips of water because they will get dehydrated - Any sick diabetic has 2 problems: - Hyperglycemia & Dehydration - Stay active as possible — helps lower glucose Acute complications - Low blood glucose (in DMT1 or 2) called hypoglycemia, hypoglycemic shock, or insulin shock/reaction - Causes: - Not enough food - Too much insulin/medication - #1 cause of hypoglycemia in diabetics — danger: permanent brain damage - Too much exercise - Signs & Symptoms: Drunk in Shock - Drunk - Staggering gait - Slurred speech - Poor judgment - Cerebral impairment (labile: all over the place; laugh, cry, laugh, cry) - Slow/delayed reaction time - Decreased social inhibition - Shock — vasomotor collapse - Low BP - Tachycardia - Tachypnea - Cold/clammy - Pale - Mottled skin Treatment - Administer sugars (rapidly metabolizable carbohydrates) - Juice (any), candy, regular soda, milk (lactose), honey, icing, jam, jelly - Boards wants combo: sugar + starch or protein - Orange juice + crackers - Apple juice + slice of turkey - Milk is sugar + protein — use ½ skim milk to they don’t burn fats for ketones - Bad answer: - Candy + soda — too much sugar - 5 packs of sugar emptied into a glass of orange juice - Unconscious patients: - Setting will determine what you give - Give Glucagon IM - Instruct mom over phone - Give Dextrose (D10, D50) IV - In ER DKA — high blood glucose in type I (keto is the clue!) - Type I — ketosis prone - Causes: - Too much food - Not enough insulin/med - Not enough exercise - None of these three are the #1 cause of DKA — the #1 cause is acute viral upper respiratory infection within last 2 weeks (stress of illness caused it to go up — started burning fat for fuel) - Signs & Symptoms: DKA - Dehydration (dry mucous membranes, weak, threads pulses, poor skin elasticity + turgor, headache, dry skin, hot, flushed, dry) - Running out of coolant/water in car — it overheats - So when you’re dehydrated, you overheat & your skin is flushed - Ketones in serum, Kussmauls, high K+ - Not everyone with ketones in urine has DKA - Kussmaul's — hyperventilate - Acidosis, Acetone breath (fruity odor), Anorexia (due to nausea) - Treatment: - Insulin IV (Regular) - IV fluids (fast rate — around 200 ml/hr) HHNK or HHS or HHNS — high blood glucose in type II - These pt don’t burn ketones = no acid - Whenever you think of HHNK, think of dehydration! - Skin is dry, warm, flushed, decreased turgor, increased HR - #1 Nursing Diagnosis — Fluid volume deficit - #1 Nursing Intervention — Rehydrate with fluids - Outcomes — Increased UOP, moist mucous membranes, etc. Between DKA & HHNK - Which is more dependent on insulin? DKA - Which one has a higher mortality rate? HHNK - Which has higher priority? - HHNK pts come later since they don’t have the symptoms — they come in when they’re already bad & may not make it - DKA pts are acutely ill that come in with all these symptoms that we can treat with rehydration with insulin Long term complications of diabetes: - Related to 2 things: poor tissue perfusion or peripheral neuropathy - Examples: Renal failure, gangrene, stasis ulcers, blindness, heart disease, brain disease, etc. - If they say, diabetics have renal failure = d/t poor tissue perfusion - If they say, diabetics lost control of bladder & are now incontinent = d/t peripheral neuropathy - Can’t feel when they injure themselves — peripheral neuropathy - Can’t heal well once they injure themselves — poor tissue perfusion Hb A1C — lab test that is the best indicator of long-term blood glucose level - Aka Glycosylated Hb — avg blood sugar over last 90 days - Want it to be 6 or lower — normal - Hb >8 — out of normal - Hb 7 — borderline; have pt come in for evaluation/work up Lecture 6 Drug Toxicities - Lithium (anti-mania drug) - Used for bipolar — not used for the depression just the mania - Therapeutic level — 0.6-1.2 - Toxic level — greater than or equal to 2 - Notice gray area — higher than 1.2 but under 2 - Lanoxin/Digoxin - Used to treat Afib & CHF - Therapeutic level — 1-2 - Toxic level — greater than or equal to 2 - If given 2, it’s safer to call something toxic when it may not be than to say it’s therapeutic when it might not be — err on safe side - Aminophylline - Airway antispasmodic — relieves spasms in airway - Therapeutic level — 10-20 - Toxic level — greater than or equal to 20 - Non-therapeutic level — lower than 10 - They need to take more or question if they’re even taking it - Dilantin/Phenytoin - Used for seizures - Therapeutic level — 10-20 - Toxic level — greater than or equal to 20 - Bilirubin - Waste product of the breakdown of RBCs - Normal adult level — 0.2-1.2 - Always tested on Newborns - Newborns have higher bilirubin than adults since they are breaking down the mother’s RBCs - Elevated level — 10-20 - Toxic level — greater than or equal to 20 - Physicians want to hospitalize newborns with bilirubin of about 14-15 - Once you hit 15, you’re halfway to toxic Patterns for toxic levels - 2s & 20s - 2s: Lithium & Lanoxin — start with L = Low number - 20s: Aminophylline, Dilantin, Bilirubin = go High Jaundice — yellow color of skin due to bilirubin in blood - Yellow skin & sclera Kernicterus — excess bilirubin in brain - Occurs when level in blood gets to around 20 - In the brain — causes aseptic (sterile) meningitis & encephalopathy due to irritation of bilirubin - Can be deadly - Causes Opisthotonos - Position that the newborn assumes when they have bilirubin in brain due to irritation of meninges - Hyperextended posture - Medical emergency - Place newborn on side Pathological vs. Physiological Jaundice - If newborn comes out yellow at birth = pathological - Something is wrong - If newborn turns yellow 2-3 days postpartum = physiological - That’s okay; typical & expected Dumping Syndrome vs. Hiatal Hernia - Both gastric emptying problems & are opposites - Hiatal Hernia - Regurgitation of gastric acid upward into esophagus - Gastric contents move in the wrong direction at the correct rate — stomach empties at a normal rate but the direction is the problem - S/S: Similar to GERD (heartburn & indigestion) - Hiatal hernia is GERD if you lie down after you eat - Treatment: want the stomach to empty faster so it doesn’t reflux/go back up - Elevate HOB during & after meals - Causes gravity to empty it faster - Increase amount of fluids with meals - Liquidity meal will go through stomach faster - Increase amount of Carb content - Carbs go through stomach fast - High-atal Hernia = everything High for tx - Dumping Syndrome - Usually follows gastric surgery - Gastric contents are dumped too quickly into duodenum - Gastric contents move in the correct direction at the wrong rate - S/S: - Drunk: staggering gait, slurred speech, impaired judgment, delayed reaction time, emotional/labile - d/t cerebral impairment from decreased blood flow to brain since all blood is going to the gut - Shock: hypotension, tachycardia, tachypnea, pale, cold, clammy - Acute Abdominal Distress: N/V, diarrhea, cramping, pain, guarding, borborygmi, bloating, distension, tenderness - Treatment: want stomach to empty slower - Lower HOB (flat) during meals & turning to side to eat - Decrease amount of fluids — 1-2 hrs before or after meals - Decrease the amount of Carb content - Everything Low = stomach empties Slow Protein in diet? - Protein does opposite of carbs - Protein bulks gastric content, takes longer to digest, & moves slower through gut - Low protein in HH - High protein in DS Electrolytes - Kalemias do the same as the prefix (hypo/hyper) except for HR & UOP - Calcemias do the opposite as the prefix - Magnesemias do the opposite as the prefix Kalemias S/S - Hyperkalemia: - Brain: seizures, agitation, restlessness, aggression, irritability, obnoxiousness, decreased inhibitions - Lungs: tachypnea - Heart: bradycardia, tall T waves, elevated ST - Bowel: diarrhea, borborygmi - Muscle: spasticity, increased tone, hyperreflexia (+3 +4) - UOP: decreased UOP/oliguria - Hypokalemia: - Lethargy, bradypnea, tachycardia, polyuria, constipation, paralytic ileus, muscle flaccidity, hyporeflexia (+1) Calcemias S/S - Hypercalcemia: - Bradycardia, bradypnea, flaccid muscles, hypoactive reflexes, lethargy, constipation - Hypocalcemia: - Agitation, Irritability (clonus), +3 +4 reflexes, spasm, seizure, tachycardia, Chvostek sign (tap cheek — cheek spasms (sign of neuromuscular irritability associated with low calcium)), Trousseau (inflate BP cuff — hand spasm) Choosing answers - For potassium — pick answers related to heart - Any other symptom not related to nerve or skeletal involvement - Generally anything affecting BP - For calcium — pick answers related to muscle & nerves/skeletal muscle & nerve involvement Common mistake - Tetany is caused by hyperkalemia not hypercalcemia even if it’s muscles! - Pay attention to the prefix! Natremias — Sodium - HypErnatremia = DEhydration - Hot, flushed, dry skin, thready pulse, rapid HR - Give fluid - HypOnatremia = Overload - Crackles, distended neck veins - Fluid restriction, Lasix - Nursing Diagnosis: Fluid volume excess Besides high potassium, what other electrolyte imbalance is possible in DKA? - Hypernatremia d/t dehydration SIADH — overload = hyponatremia DI — dehydration = hypernatremia HHNK — dehydration = hypernatremia Earliest sign of any electrolyte disorder - Paresthesia = numbness & tingling - Circumoral paresthesia = numb & tingling around lips Universal sign of all electrolyte imbalance - Paresis = Muscle weakness Treatment - Potassium is the only one boards will test - NEVER push potassium IV - Not more than 40 of K per L of IV fluid - If you receive an order of more than 40 — question, call, & verify with HCP How To Lower Potassium - High potassium is bad — can stop the heart - High potassium is the worst electrolyte imbalance - Fastest way to lower potassium: - Give D5W with regular insulin — drives potassium into cells & out of blood to decrease potassium (potassium in blood will kill you — not the potassium in the cells) - Doesn’t get rid of excess potassium but hides it in the cell - Good side: Quick - Bad side: Temporary solution — potassium will just leak back out - Long-term solution: Kayexalate/Sodium polystyrene sulfonate - Through enema or ingestion - Full of sodium — trades potassium for sodium - Potassium is eliminated through feces & pt becomes hypernatremic - Hypernatremic = dehydration - Managed with IV fluid administration - Good side: Permanent — gets rid of potassium outside of body never to reoccur - Bad side: Takes hours to work - To solve problem: - Give them both — D5W & regular insulin & Kayexalate at the same time - D5W & regular insulin work instantly — K Enters Early - Potassium — K - Makes K enter cell - Does it quick/early - Kayexalate works in a few hours — K Exits Late - Potassium — K - Makes K exit out body - Does it slow/late Lecture 7 Thyroid & Adrenals - Thyroidism = Metabolism - Hyperthyroidism — Hypermetabolism — Graves Disease - S/S: Weight loss, HR up, BP up, Hyperpersonality (irritable, hyper, obnoxious, excited), heat intolerance (they’re already burning up), cold tolerance (they’re like a furnace; cold doesn’t affect them), exophthalmos (bulging eyes) - “You’re going to run yourself into the grave-s disease” — running all the time = hyper - Treatment - Radioactive iodine - Pt should be in a private room by themselves for 24 hrs — after that, they have to be really careful with their urine (flush 3x, call hazmat team if they spill on the floor) - No family visitation in first 24 hrs — if at home, they need to stay in room & no one can go in for 24 hrs - PTU (Propylthioruracil) — Puts Thyroid Under - Primary use: Cancer — monitor WBC d/t immunosuppression - Thyroidectomy - Surgical removal — most common tx - Pay attention if question is asking about total or sub (partial) - Total thyroidectomy: lifelong hormone replacement - Thyroid is gone & pt is at risk for hypocalcemia (almost impossible to spare the parathyroids) - Hypocalcemia S/S: - Paraesthesia, tetany, spasms, clonus, seizures, tachycardia, hypertension, irritability, jitteriness, tremor, Chvostek & Trousseau signs - Sub Thyroidectomy: do not need lifelong hormone replacement - Still have some thyroid left; may need to be on replacement/supplement for a little while - Risk for thyroid storm/crisis/thyrotoxicosis: medical emergency! (Can cause brain damage — permanent) - S/S: - Super high temp 105 or above - Extremely high BP — stroke category (about 210/180) - Severe tachycardia (180s & high as 200s) - Psychotically delirious - Treatment: get temp down & oxygen up! - First step: Ice packs - Best step: Cooling blanket - Oxygen per mask at 10L - Stay with patient - Self-limiting condition — not really medicating; all we’re doing is sparing their brain until pt comes out of it - Post-op Risks: - First 12 hrs (doesn’t matter what type) - Top priority — airway (d/t edema) - Next problem — hemorrhage (since it is an endocrine gland which has lots of blood vessels) - Next 12-48 hrs (type matters) - Total: big danger = tetany (d/t low calcium) - Dangerous since it could close vocal cords in irreversible spasm = airway gets cut off - Total = Tetany - Subtotal: big danger = thyroid storm - Sub = Storm - After 72 hrs, big risk = infection - Hypothyroidism — Hypometabolism — Myxedema - S/S: Weight gain (obese), Hypopersonality (flat, boring, dull), cold intolerance, heat tolerance (can’t tolerate what you are), HR down, BP down, academically challenged (slow test takers, lower grades = can’t process fast enough) - Treatment: - Give hormones d/t not enough hormones — Levothyroxine (Synthroid) - Caution: - DO NOT sedate - They’re already super slow— could go into coma = myxedema coma - DO NOT hold thyroid pills unless explicitly ordered — especially before surgery (d/t suppressing effects of anesthesia) Adrenal Cortex - All adrenal cortex diseases start with A or C (Addison Disease, Cushing) - Addison Disease - Under secretion of adrenal cortex - S/S: - Hyperpigmented (very tan) - Do not adapt to stress - Purpose of stress response: to perfuse brain with blood & give brain glucose (raise glucose & BP) - With Addison Disease, when they undergo stress — glucose & BP will go down = shock - Treatment: - Steroids - Glucocorticoids — end in -sone - “In Addison, you ADD a SONE” - Cushing’s Syndrome - Oversecretion of adrenal cortex - “Cushy bank account = more money” - S/S: (of both Cushing’s & Steroid medications) - Moon face - Hirsutism (beard) - Truncal/Central obesity (big body) - Muscle atrophy (arms & legs are skinny) - Gynecomastia (big breasts/bump on front) - Buffalo hump (bump on back) - Retaining sodium & water (full of water) - Loss of K+ (out the back) - Striae (stretch marks) - High serum glucose - Most important — hyperglycemics; look like diabetics - Need more insulin d/t steroid use - Accu-checks Q6H - Easy bruising (bruises) - “Roid rage” (grouchy/irritable) - Immunosuppressed - Treatment: - Adrenalectomy - Bilateral adrenalectomy = Addison’s - Give steroids (sone) to treat - Steroids can have side effects that cause pt to look like Cushman - Takes about a year or two to get pt to start looking/feeling normal Kids Toys - Things to consider when choosing toys & play activities: - Is it safe? - Is it age appropriate? - Is it feasible? (Possible to do easily/conveniently) - Safety: - No small toys for children under 4 - Over 4 — small parts are fine - No metal (dye-cast) toys if oxygen is in use - Due to flint-sparks - Beware of fomites - Non-living object that harbors microorganisms (stuffed animals — worst fomites) - Hard plastic toys are fine — easily disinfected - Age Appropriate: - Infants: - 0-6 months - Sensorimotor (something that stimulates both motor & sensory) - Best: Musical mobile - 2nd best: Toy that should be large but soft (so they don’t hurt themselves or choke) - 6-9 months - Object permanence (concept that the object is still there even if they can’t see it) - Best: Cover/Uncover toys - Teaching them that concept - Examples: Jack in the Box, Peek a Boo, books that have windows - 2nd best: Toy that should be large but firm/hard (wood, metal, plastic) - Worst toy after 6 months — musical mobile d/t risk of strangulation - 9-12 months - Vocalization (learning to speak) - Best: Speaking/Verbal toys - Examples: Woody Cowboy, Tickle me Elmo, See and say barnyard friends, Talking books - Purposeful play — should be at least 9 months - Purpose words: build, sort, stack, make, & construct - Toddlers: - 1-3 years - Gross motor skills (run, jump) - Best: Push/Pull toys - Examples: Lawn mower, wagon, strollers, dogs with floppy feet - DO NOT choose activities that take finger dexterity — colored pencils, scissors, etc. - They CAN paint (use hands) - Characterized by Parallel Play (play alongside others but not with others) - Preschoolers: - 3-6 years - Fine motor skills (finger dexterity — write, draw, use colored pencils, scissors - Balance (dance, ice skates, tricycles, tumbling) - Characterized by Cooperative Play (play with others) - Like to pretend — highly imaginative - School age: - 7-11 years - Concrete - Characterized by 3 C’s: - Creative - Give them blank paper to draw, they make whatever they’re playing - Toys: Legos, Transformers - Collective - Beanie bears, Pokémon, Baseball cards, Barbies - Competitive - Winner/losers (don’t like being the loser but like playing games where there is a winner & losers) - Adolescents: - 12-18 years - Peer group association (want to hang out with friends) - Allow adolescents to be in each other’s room unless one of them has been/is: - Recently post-op for 30 mins - Lie flat, log roll for 6 weeks - DO NOT drive for 6 weeks - DO NOT lift more than 5 lbs for 6 weeks (gallon of milk) - Permanent restrictions: - Laminectomy patients will never be allowed to lift objects by bending at waist (use knees) - Cervical laminectomy should never be allowed to lift anything over the head - No horseback riding, off trail biking, jerky amusement park rides, etc. Lecture 8 Lab Values - Need to know lab values & which one is low, middle, high priority when compared to others — prioritize patients - Not enough to just know normal/abnormal values - ABCD scheme - A — low priority (abnormal but no big deal; don’t have to do anything about it — can be ignored for a few hours, all night long, & have doctor discover it in the morning) - B — concerning (abnormal & need to be concerned but there’s nothing to be done — just watch closely) - C — critical (you must do something about it) - D — highest priority (stay at bedside — can’t leave) - Creatinine — best indicator of kidney or renal function - Range: 0.6-1.2 - Level A (never prioritize a pt with high creatinine as high priority; they do have kidney disease but won’t die in the next few hours) - If pt will have dye procedure like catheterization — can be moved to Level B - INR — monitors Coumadin therapy; variation of PT - Range: 2-3 - Level C (if 4 & above) - Actions: Hold Coumadin —> Focus Assessment for bleeding —> Prepare to give Vit K —> Call HCP - Potassium - Range: 3.5-5.3 - Level C (if lower than 3.5) - Actions: Nothing to hold —> Focus Assessment of heart —> Prepare to give K+ —> Call HCP - Level C (if higher than 5.3) - Actions: Hold K+ —> Focus Assessment of heart —> Prepare to give Regular Insulin/Kayexalate & D5W—> Call HCP - Level D (if over 6) - Actions: Hold K+ —> Focus Assessment of heart —> Prepare to give Regular Insulin/Kayexalate & D5W STAT —> Call HCP & stay with pt - pH - Range: 7.35-7.45 - Level D (if pH is in the 6s) - Actions: Nothing to hold —> Focus Assessment of V/S —> Nothing to prepare —> Call HCP & stay with pt - BUN (Blood Urea Nitrogen) — waste product in blood - Range: 8-25 - Level A - Actions if elevated (no big deal): Nothing to hold —> Focus Assessment for dehydration —> Prepare IV fluid —> Call HCP - Hemoglobin — blood - Range: 12-18 - Level B (if 8-11) - Assess them for bleeding/anemia/malnutrition - Level C (if less than 8) - Actions: Nothing to hold —> Focus Assessment for bleeding/anemia/malnutrition —> Prepare blood —> Call HCP - Bicarbonate - Range: 22-26 - Level A - CO2 - Range: 35-45 - Level C (if in 50s) - Actions: Nothing to hold —> Focus Assessment of breathing/respiratory status —> Ask pt to perform pursed-lip breathing (prolonging exhaling to get rid of CO2) —> Call HCP - Not a COPD pt - Most of the time the pursed lip breathing will fix so you don't’ have to call — they breathe easier instead of being dyspneic - Level D (if in 60s or higher) — one of the criteria to make it respiratory failure - Actions: Nothing to hold —> Focus Assessment of breathing/respiratory status —> Prepare to intubate/ventilate —> Call (RT first & then HCP) & stay with pt - Hematocrit - Range: 36-54 (remember by mult 3 to Hgb) - Level B - Actions if elevated: Assess for dehydration - O2/PaO2 (from arterial blood gas NOT pulse ox) - Range: 78-100 - Level C (if 70-77) - Actions: Nothing to hold —> Focus Assessment for respiratory difficulty & dyspnea —> Prepare to give oxygen —> Call HCP - If pt with hypoxia — HR increases first & then RR increases after d/t compensation - In a coronary care unit, the two most common causes of episodic tachycardia in heart pt = hypoxia & dehydration - Treatment: giving O2 to pt & increasing rate of fluid administration usually solves the problem - Know it worked when dyspnea, restlessness, tachycardia, & anxiety goes away - Level D (if in the 60s or lower) — other criteria to make it respiratory failure - Actions: Nothing to hold —> Assessment for respiratory difficulty & dyspnea —> Prepare to intubate/ventilate —> Call (RT first then HCP) & stay with pt - Can put oxygen on pt — won’t solve problem but will make them more calm - *Resp failure — CO2 & O2 both in 60s = intubate/ventilate! - COPD pts have various ranges (usually high on CO2 & low on O2) - *Assess before you do — unless delaying doing put pt at higher risk (in that case, do before you assess) - *Other example: - Best: Oxygen - First: Elevate HOB - O2 Saturation - Range: 93-100 - Level C (if less than 93) - Action: Nothing to hold —> Assess —> Give pt O2 —> Call HCP - Less than 95 is bad in peds cause they don’t desaturate like adults - What could invalidate reading? - Anemia & dye procedure in last 48 hrs (colors blood) - Both are falsely elevated — seems like pt is better off than they actually are - BNP (brain natriuretic peptide) — best indicator for CHF - Range: Assess for fluid overload (hyponatremia)/Assess for dehydration (hypernatremia) —> Prepare for furosemide (hyponatremia)/IV fluid (hypernatremia) —> Call HCP - Level C (if abnormal & there is a change in pt LOC) - Safety issue - WBC - Total WBC: 5k-11k - Level C (if less than 5k) - ANC (absolute neutrophil count): >500 - Level C (if less than 500) - CD4: >200 - HIV = CD4 >200 but Place pt on neutropenic precautions - Platelet - Range: 150k-450k - Level C (if less than 90k) - Level D (if less than 40k) - Place pt on bleeding precautions - RBC - Range: 4-6 million - Level B (if abnormal) Five Deadly D’s - K+ in the 6s - pH in the 6s - CO2 in the 60s - O2 in the 60s - Plt