Lymphatic System PDF Study Notes
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Loyola Marymount University
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Summary
This document provides an overview of the lymphatic system, including its function in fluid drainage and immune response. It explains the components of the lymphatic system and how it works within the body's larger circulatory and immune systems.
Full Transcript
The Lymphatic System 8/27/24, 3:46 PM Platform | Study Fetch (00:00:12 - 00:00:23)The lymphatic system is a network of lymph nodes and vessels that get rid of unwanted materials from the body. It connects with the circulatory and...
The Lymphatic System 8/27/24, 3:46 PM Platform | Study Fetch (00:00:12 - 00:00:23)The lymphatic system is a network of lymph nodes and vessels that get rid of unwanted materials from the body. It connects with the circulatory and immune system. Lesson Overview: The lymphatic system Lymphatic vessels Lymph nodes (00:00:34 - 00:00:47)The Lymphatic System: Lymphatic vessels and organs make up the lymphatic system This includes lymphatic ducts, lymph nodes, and the thymus These structures contribute to the immune system and the lymphatic system (00:00:58 - 00:01:16)Lymphatic Vessels: Lymphatic vessels collect the interstitial fluid from capillary beds during nutrient exchange This fluid is forced out of the small capillaries and into the tissue, carrying nutrients "Lymphatic vessels collect the interstitial fluid from vas capillary beds during nutrient exchange. And this is important to remember. So you have our pressure going into our capillary beds and this is going to force out some fluid from the small capillaries." (00:01:16 - 00:01:30) The interstitial fluid that is forced out of the capillaries carries nutrients with it Fluid Dynamics and the Lymphatic System (00:01:30 - 00:01:45) Fluid exchange between the capillaries and tissues is driven by oncotic pressure Oncotic pressure is the pressure exerted by proteins like albumin that draw fluid back into the capillaries However, a small fraction of the fluid remains in the tissues and needs to be drained (00:01:45 - 00:01:59) If the lymphatic system is blocked, this can lead to edema or fluid buildup in the tissues The lymphatic system provides an alternative method to drain this excess fluid from the tissues (00:01:59 - 00:02:10) Draining the excess fluid through the lymphatic system is important to prevent too much fluid accumulation in the tissues This fluid drainage provides an opportunity for the immune system to screen the fluid for any foreign invaders (00:02:10 - 00:02:24) The lymphatic system drains the extra fluid from local tissues https://www.studyfetch.com/platform/studyset/66cd116dd279f5220d947c66/material/66ce2ca815efc412ba2f7d62/document?go=note 1/4 This fluid drainage allows the immune system to screen the fluid for any potential threats 8/27/24, 3:46 PM Platform | Study Fetch (00:02:24 - 00:02:38)Diagram of the Cardiovascular and Lymphatic Systems: The heart pumps blood through the circulatory system Fluid exchange occurs between the capillaries and tissues Excess fluid is drained through the lymphatic system Key Points: Oncotic pressure drives fluid exchange between capillaries and tissues Lymphatic system drains excess fluid from tissues to prevent edema Lymphatic drainage provides an opportunity for immune system surveillance The Lymphatic System (00:02:38 - 00:02:48) Fluid from the capillary bed is forced out into the interstitial fluid surrounding the tissues. This interstitial fluid then drains into the lymphatic capillaries. (00:02:48 - 00:03:05) The lymphatic capillaries carry the fluid to a lymph node. In the lymph node, the fluid undergoes immune surveillance to check for any invaders or pathogens. After passing through the lymph node, the fluid returns to the circulatory system via the lymphatic ducts. (00:03:05 - 00:03:16) The lymphatic system helps the body remove excess fluid from the tissues. It also uses this fluid drainage for immune surveillance. (00:03:16 - 00:03:29) The major lymphatic vessels drain into the large veins of the neck, specifically the subclavian veins just before the brachiocephalic vein on the left side. (00:03:29 - 00:03:41) The right lymphatic duct drains lymph from the right upper quadrant of the body. The thoracic duct, also known as the left lymphatic duct, drains lymph from everywhere else in the body. Key Terms and Concepts: Interstitial Fluid: The fluid that surrounds the body's cells and tissues. Lymphatic Capillaries: The smallest lymphatic vessels that drain the interstitial fluid. Lymph Nodes: Organs that filter lymph fluid and provide immune surveillance. Lymphatic Ducts: The vessels that return lymph fluid to the circulatory system. Right Lymphatic Duct: Drains lymph from the right upper quadrant of the body. Thoracic Duct (Left Lymphatic Duct): Drains lymph from the rest of the body. Importance of the Lymphatic System: Removes excess fluid and waste from the body's tissues. Provides a route for immune cells and substances to circulate and monitor for infections or diseases. Plays a crucial role in the body's overall immune response. https://www.studyfetch.com/platform/studyset/66cd116dd279f5220d947c66/material/66ce2ca815efc412ba2f7d62/document?go=note 2/4 8/27/24, 3:46 PM Platform | Study Fetch Lymphatic System Drainage (00:03:41 - 00:03:58) The lymphatic system drains fluid from the left side of the body The lymphatic ducts come up around the collarbone area and then drain back into the circulatory system (00:03:58 - 00:04:08) Lymphatic fluid drains from the capillary beds, up through the lymph nodes, and then back into the circulatory system This completes the lymphatic drainage circuit (00:04:08 - 00:04:30) The right lymphatic duct drains the right side of the body, including the right torso, head, arm, and thorax Remembering that the right duct drains the upper right side can help you recall this system (00:04:30 - 00:04:40) The thoracic duct drains everything else in the body except the right upper quadrant Knowing this can help you answer questions about lymphatic drainage (00:04:40 - 00:04:55) Lymph nodes contain immune system cells that can screen for pathogens Lymph nodes are important areas for the immune system to function Key Terms and Concepts: Lymphatic ducts Circulatory system Capillary beds Lymph nodes Right lymphatic duct Thoracic duct Immune system cells Lymphatic Drainage Mnemonic: Right lymphatic duct drains the right torso (T), head (H), arm (A), and thorax (T) Importance of Lymph Nodes: Screen for pathogens Contain immune system cells Critical for immune system function The Lymphatic System and Immune Cells https://www.studyfetch.com/platform/studyset/66cd116dd279f5220d947c66/material/66ce2ca815efc412ba2f7d62/document?go=note 3/4 (00:04:55 - 00:05:07) 8/27/24, 3:46 PM Platform | Study Fetch The lymphatic system helps filter out any foreign invaders that may have entered the local tissue. If you have a skin infection, the lymph would drain through the lymphatic system and go to the local lymph node, where it would pick up anything that shouldn't be there. (00:05:07 - 00:05:25)Immune Cells in the Lymph Nodes: Lymph nodes contain lymphocytes, which include: B lymphocytes T lymphocytes Macrophages The words "lymph" and "lymph nodes" should remind you of lymphocytes, as they are all connected. (00:05:25 - 00:05:37) Lymphocytes and macrophages are the major types of cells found in the lymph nodes. Macrophages also play an important role in the lymph nodes. (00:05:37 - 00:05:52) The lymphatic system and immune system are closely integrated and work together. We'll be covering more specific cell types and details about the immune system in the upcoming sections. It's important to understand how the lymphatic system and its ducts and drainage are connected to the immune system and how they all work together. https://www.studyfetch.com/platform/studyset/66cd116dd279f5220d947c66/material/66ce2ca815efc412ba2f7d62/document?go=note 4/4