Lower Respiratory Drugs KEY (2) PDF

+-------------+-------------+-------------+-------------+-------------+ | **Class** | **Action** | **Indicatio | **Adverse | **Misc** | | | | ns** | Effects** | | +=============+=============+=============+=============+=============+ | **Sympatho...

+-------------+-------------+-------------+-------------+-------------+ | **Class** | **Action** | **Indicatio | **Adverse | **Misc** | | | | ns** | Effects** | | +=============+=============+=============+=============+=============+ | **Sympathom | Stimulates | **Albuterol | CNS: | **Caution** | | imetics/** | beta2 | :** | tremors, | : | | | adrenergic | | headaches, | cardiac | | **Alpha and | receptors | Treat | restlessnes | dysrhythmia | | Beta 2 | in the | asthma | s | s, | | Adrenergic | lungs \--\> | | | heart | | Agonists** | relaxation | Prophylaxis | CV: | failure, | | | of | and | tachycardia | cardiac | | **Albuterol | bronchial | treatment | and | disease, | | ** | smooth | of | palpitation | diabetes | | | muscle\--\> | bronchospas | s | | | **Salmetero | bronchodila | m | (with high | Given via | | l** | tion | | doses) | inhaler or | | | | **Salmetero | | nebulizer | | | | l:** | Hyperglycem | | | | | asthma, | ia | Salmeterol | | | | COPD and | | use 1 puff | | | | exercise-in | | at least 30 | | | | duced | | minutes | | | | bronchospas | | before | | | | m | | exercise | | | | prophylaxis | | | | | | | | Can develop | | | | | | tolerance | | | | | | | | | | | | Monitor | | | | | | glucose | | | | | | levels | +-------------+-------------+-------------+-------------+-------------+ | **Anticholi | Blocks | COPD | **CNS:** | **Contraind | | nergic** | muscarinic | | headache, | ications**: | | | cholinergic | Allergy | blurred | | | **Ipratropi | receptors | induced | vision | allergy to | | um** | and | asthma | | soy or | | | antagonizes | | **GI:** | peanuts | | | acetylcholi | Bronchospas | dyspepsia, | | | | ne | m | dry mouth | **Caution:* | | | by | due to the | | * | | | inhibiting | common cold | **CV:** | BPH, | | | M3 receptor | | Palpitation | glaucoma | | | response to | | s | | | | acetylcholi | | | Commonly | | | ne | | **GU:** | used in | | | \--\> | | urinary | combination | | | relaxing | | retention | with | | | smooth | | | albuterol | | | muscle of | | Less | for | | | bronchi | | adverse | enhanced | | | | | effects | effectivene | | | \--\>dilati | | than other | ss | | | on | | drugs in | and longer | | | | | this class | duration of | | | | | | | | | | | | Action | | | | | | | | | | | | Given | | | | | | inhalation | | | | | | or | | | | | | nebulizer | +-------------+-------------+-------------+-------------+-------------+ | **Xanthines | Inhibits | Maintenance | **CNS:** | **Contraind | | ** | phosphodies | therapy in | irritabilit | icated:** | | | terase | chronic | y, | seizure | | **Aminophyl | which | stable | headaches, | disorders, | | line/Theoph | increases | asthma and | restlessnes | cardiac, | | ylline** | cAMP | COPD when | s, | renal or | | | \--\>relaxa | other drugs | insomnia, | liver | | | tion | have failed | dizziness, | disease | | | of smooth | | seizures | | | | muscle of | | | **Therapeut | | | bronchi, | | **GI:** | ic | | | bronchioles | | anorexia, | level** | | | and | | nausea, | 10-20 | | | pulmonary | | vomiting, | mcg/mL | | | blood | | diarrhea, | | | | vessels\--\ | | gastric | Given: PO | | | > | | pain | or IV | | | bronchodila | | | | | | tion | | **CV:** | Smoking | | | | | palpitation | increases | | | | | s, | metabolism | | | | | tachycardia | \--\>decrea | | | | | , | sing | | | | | arrhythmias | half-life | | | | | , | \--\> | | | | | hypotension | increased | | | | | | dose | | | | | Hyperglycem | requirement | | | | | ia | s | | | | | | | | | | | Decreased | Avoid: | | | | | clotting | caffeinated | | | | | time | products | | | | | | | | | | | **Rapid IV | Given on IV | | | | | administrat | pump | | | | | ion:** | | | | | | dizziness, | Increases | | | | | flushing, | risk of | | | | | hypotension | digoxin | | | | | , | toxicity | | | | | severe | | | | | | bradycardia | Betablocker | | | | | and | s | | | | | palpations | increase | | | | | | effects | | | | | | | | | | | | If given | | | | | | with beta | | | | | | adrenergic | | | | | | agonists | | | | | | can get | | | | | | cardiac | | | | | | dysrhythmia | | | | | | s | +-------------+-------------+-------------+-------------+-------------+ | **Class** | **Action** | **Indicatio | **Adverse | **Misc** | | | | ns** | Effects** | | +-------------+-------------+-------------+-------------+-------------+ | **Leukotrie | Binds with | Allergic | **CNS:** | Caution: | | ne | leukotriene | rhinitis | headache, | hepatic | | Receptor | receptors | | dizziness, | dysfunction | | Antagonists | to inhibit | Chronic or | insomnia, | | | and | smooth | exercise | irritabilit | Given PO, 1 | | synthesis | muscle | induced | y, | hour before | | inhibitors* | contraction | Asthma | depression, | or 2 hours | | * | and | | anxiety | after meals | | | bronchocons | Not for | hallucinati | | | **Monteluka | triction | acute | ons | Safe for | | st** | | attacks, | suicidal | children 2 | | | | prophylacti | thinking | years and | | | | c | | older | | | | and | **GI:** | | | | | maintenance | nausea, | | | | | therapy | vomiting, | | | | | only | dyspepsia, | | | | | | diarrhea | | +-------------+-------------+-------------+-------------+-------------+ | **Inhaled | Anti-inflam | Asthma that | **Local:** | Takes 1-4 | | steroids** | matory | is | throat | weeks to | | | effect | unresponsiv | irritation, | reach | | **Budesonid | | e | hoarseness, | effective | | e** | | to | dry mouth, | levels | | | | bronchodila | coughing | | | | | tor | | Given via | | | | therapy | Fungal | inhaler | | | | | infections | | | | | Asthma | | Not for | | | | attack | | emergency | | | | while on | | use or | | | | max doses | | acute | | | | of | | attack | | | | theophyllin | | | | | | e | | To prevent | | | | or | | fungal | | | | adrenergic | | infections, | | | | drug | | use a | | | | | | spacer and | | | | | | rinse mouth | | | | | | and throat | | | | | | after each | | | | | | dose, wash | | | | | | deliver | | | | | | apparatus | | | | | | with warm | | | | | | water daily | +-------------+-------------+-------------+-------------+-------------+