Summary

This document provides an in-depth study or notes on nucleic acids, covering monomeric units, DNA, RNA structures, and interactions. It discusses the important differences between DNA and RNA components and details crucial concepts.

Full Transcript

Note that monomeric units are parts of a polymer, the chains continue outside of our drawing! The little dashes (apostrophe) next to the 5 and 3 indicate prime! 5’ refers to the 5’-carbon in deoxyribose, while 3’ refers to the 3’-carbonin deoxyribose. Thymine and Uracil are structurally very similar...

Note that monomeric units are parts of a polymer, the chains continue outside of our drawing! The little dashes (apostrophe) next to the 5 and 3 indicate prime! 5’ refers to the 5’-carbon in deoxyribose, while 3’ refers to the 3’-carbonin deoxyribose. Thymine and Uracil are structurally very similar, differing only by a methyl group on Thymine! There are regions of double stranded DNA that need to have strands separate sometimes (e.g., to begin DNA replication or transcription), and these regions tend to be rich in A-T, which is easier to separate than G-C. Drawing a 3D double helix is super important to do well, so please note how it looks to be drawn out correctly! This Stem Loop structure is found in tRNA which is very important for Translation! (We’ll get there later) Not a universal abbreviation, but useful for the purposes of this course Remember our ATP structure from Unit 2 to recall what makes ATP unstable and breakable! (Though this is dATP, the same principle applies.) We left off here, we will resume this topic on Monday!