Summary

This document provides an overview of the history of immunology and the components of the immune system. It defines key terms and details the different types of immunity, including innate and adaptive immunity. The paper also examines examples, the cells involved, and the response times in each type of immunity.

Full Transcript

History of Immunology Immune System Definition of Terms Innate DIFF INNATE ADAPTIVE First line and secondlinebarriers IMMUNITY IMMUNITY Adaptive Humoral-mediated immunity...

History of Immunology Immune System Definition of Terms Innate DIFF INNATE ADAPTIVE First line and secondlinebarriers IMMUNITY IMMUNITY Adaptive Humoral-mediated immunity AKA NONSPECIFIC ACQUIRED NATURAL SPECIFIC Cell-mediatedimmunity Active immunity Ability to resist body function Passiveimmunity infection by First line of Antigens and Immunogens F means of normal defense against body function pathogens First line of Ability to Definition of Terms defense against remember a prior Immunology pathogens exposure to a Stevens: Study of host’s reactions to foreign specific pathogen substances that are introduced to Second line of the body defense Turgeon : Resistance to disease, specifically EXAMPLES Physical barriers T cells & B cells infectious disease; and consists of the Chemical barriers Vaccination molecules, cells, organs, and systems Cellular Humoral Cellular Humoral responsible for the recognition and disposal of foreign (nonself) material; how CELLS Leukocytes in the B cells and body components respond and INVOLVED blood Tissue cells plasma cells T (macrophages, cells NK cells interact; the desirable and undesirable mast cells, consequences of immune interactions; dendritic cell) and the ways in which the immune system can be advantageously manipulated Response Short and Slower than to protect against or treat disease Time immediate innate Specificity Slower than Specific Immunity innate Condition which is resistant to infection Antigens Potency Low potency High potency Substances that induces immune response Inheritance / May be present X Develops over Antibodies at birth a lifespan Serum proteins produced by lymphocytes when exposed to a foreign Other notes NO MEMORY PRESENCE OF substance MEMORY Phagocytosis “Cells eating cells” NATURAL IMMUNITY vs. ADAPTIVE IMMUNITY ACTIVE - Individual produces antibody follows immunization or infection memory NATURAL (innate) ADAPTIVE ( Acquired) (lasting) PASSIVE Non- specific Specific - Antibody transferred to individual No memory example : gamma globulin injections. Memory Placental transfer example : - exogenous (skin) Examples: No memory ( temporary) - Endogenous T cells (cytokines) What type of immunity is associated with (stomach acid) B cells (antibodies) rubella immunization? Active immunity - Phagocytosis What type of immunity is associated with (PMNS) neonatal (

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