WhatsApp Image 2025-02-05 at 19.46.04.jpeg

# La sinapsis ## Potencial postsináptico * Los agentes químicos del interior de los neurotransmisores pueden tener dos efectos: * **Potenciales Postsinápticos Excitatorios (PPE)** → Despolariza * **Potenciales Postsinápticos Inhibitorios (PPI)** → Hiperpolariza *(Diagram with two graphs and a neu...

# La sinapsis ## Potencial postsináptico * Los agentes químicos del interior de los neurotransmisores pueden tener dos efectos: * **Potenciales Postsinápticos Excitatorios (PPE)** → Despolariza * **Potenciales Postsinápticos Inhibitorios (PPI)** → Hiperpolariza *(Diagram with two graphs and a neuron diagram)* **Description:** The diagram illustrates the concept of excitatory and inhibitory postsynaptic potentials (EPSPs and IPSPs).  A neuron (the presynaptic neuron) is shown sending a signal to another neuron (the postsynaptic neuron) through a synapse. **(Graph 1 for PPE)** The graph displays the change in membrane potential (mV) over time (ms) for a presynaptic and a postsynaptic neuron when excitatory signal occurs. The Presynaptic neuron shows a sharp increase in membrane potential. The postsynaptic neuron's membrane potential depolarizes accordingly. Notice the positive peak that appears briefly. This is known as an EPSP, it makes the membrane potential in the postsynaptic neuron more positive, bringing it closer to the threshold for an action potential. **(Graph 2 for PPI)** Another graph is shown similar to the first one for the presynaptic neuron and postsynaptic neurons when an inhibitory signal occurs. An inhibitory signal is shown, the Presynaptic neuron shows a rapid decrease in membrane potential. The postsynaptic neuron's membrane potential hyperpolarizes accordingly. This is known as an IPSP, it makes the membrane potential in the postsynaptic neuron more negative, moving it away from the threshold for an action potential. *In the figure, the pre-synaptic neuron is releasing a neurotransmitter that produces an excitatory postsynaptic potential (EPSP) and a post-synaptic potential (PP) or inhibitory postsynaptic potential (IPSP) in the post-synaptic neuron. The figure is a schematic representation of the mechanism involved in neuronal communication.* *Neurons can be either excitatory or inhibitory based on their effect on the postsynaptic potential and not on the conduct.*