Intracellular Compartments and Protein Sorting PDF
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Universidad Complutense de Madrid
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Summary
This document details the location of DNA in eukaryotes, the functions of the inner and outer membranes, and the selective transport of materials across the nuclear envelope. It also discusses energy production, oxidative metabolism, protein sorting, and other related biological concepts.
Full Transcript
Location of DNA in eukaryotes **Main Functions**:...
Location of DNA in eukaryotes **Main Functions**: Site of DNA replication, transcription, and RNA modification This double membrane structure (inner and outer membrane) separates nuclear content from the cytoplasm. It has pores allowing selective exchange of materials **Perinuclear Space**: Located between the inner and outer membranes Structure: Composed of nucleoporins arranged in octagonal symmetry with a central channel and outer and inner rings **Main Functions**: Energy production via oxidative metabolism Nuclear Localization Signal (NLS): If a protein want to enter the nucleus it must have this Signals Outer Membrane charged amino acids like lysine - Contains porins for passive molecule transport (
