MEDT 4531 Immunology Exam Study Guide PDF

# Study Guide MEDT 4531 Examen Módulo 1 ## Question 1 Which is the most significant agent formed in the phagolysosome for the killing of microorganisms? ## Question 2 The first line of defense against infection is: ## Question 3 The presence of normal flora acts as a defense mechanism by which of th...

# Study Guide MEDT 4531 Examen Módulo 1 ## Question 1 Which is the most significant agent formed in the phagolysosome for the killing of microorganisms? ## Question 2 The first line of defense against infection is: ## Question 3 The presence of normal flora acts as a defense mechanism by which of the following ways? ## Question 4 Enhancement of phagocytosis by a coating of foreign particles with serum proteins is called: ## Question 5 Skin, lactic acid secretions, stomach pH, and cilia motility represent which type of immunity? ## Question 6 Which of the following can be attributed to antigen-stimulated T cells ## Question 7 Which of the following is a primary lymphoid organ? ## Question 8 Which of the following is true description of NK cells? ## Question 9 MHC antigens are associated with all except: ## Question 10 All the following are true description of IgM except that it: ## Question 11 Which of the following are light chains of antibody molecules? ## Question 12 Which interferon acts as an activating factor for macrophages? ## Question 13 Which is the correct order for activation of the components in the classical pathway? ## Question 14 The classic component pathway is initiated by interaction of C1 with ## Question 15 The membrane IgM and IgD on the surface of an individual B cell ## Question 16 Cytotoxic T cells induced by an infection with virus A will kill target cells ## Question 17 Graft and tumor rejection are mediated primarily by ## Question 18 Normal controls for a quantitative B lymphocytes assay should have a value of what percentage of total lymphocytes counted? ## Question 19 Refer to the following results for peripheral blood samples. | Patient | % T lymphocytes | |---|---| | Patient 1 | 85% | | Patient 2 | 23% | | Patient 3 | 50% | | Patient 4 | 82% | | Normal control | 44% | The data above indicates: ## Question 20 Refer to the following results for peripheral blood sample flow cytometric data. Absolute WBC: 8, 930 / mm³ Total lymphocytes: 30% B lymphocytes: 40% T lymphocytes: 58% Calculate the absolute count for B lymphocytes: ## Question 21 Refer to the following results for a peripheral blood sample. Total WBC 10.0 × 10³/dL | Differential | percentage | |---|---| | Neutrophils | 68% | | Lymphocytes | 25% (40% T cells) | | Monocytes | 4% | | Eosinophils | 2% | | Basophils | 1% | The expected number of T cells is: ## Question 22 Match cells descriptions 1. Release lymphokinins. Regulates cellular immunity. They contain CD1 and CD2 in the membrane. It requires the intervention of macrophages to activate. Generates cytotoxic cells. 2. Generates plasma cells. They mature in lymph nodes, bone marrow, or the spleen. ## Question 23 Match cells descriptions 1. destroys microorganism or cells infected by viruses 2. recognizes the antigen that previously invaded the body 3. inhibits antibody production 4. stimulates the "helper" 5. induces the formation of antibodies 6. causes allergies 7. fight cancer ## Question 24 Match descriptions 1. delays the degradation of C3 convertase 2. potent anaphyllotoxin 3. formed 6 triple helix molecules that attach to the Fc portion 4. formed by 6 molecules and creates a tunnel in the cell membrane 5. most abundant complement factor 6. component of the complex that initiates the attack on the cell membrane 7. enzyme (protease) that breaks down C4 and C2 8. sequence activated by viruses, IgA, bacteria and cobra venom 9 sequence activated by IgM and IgG molecules 10. C3 convertase ## Question 25 Match with definitions 1. Xenotransplants 2. Alotransplantes 3. Isotranplants 4. Autotransplants ## Question 26 Match chronic, acute, accelerate, hyperacute 1. takes months, precipitation immune complexes in transplant 2. takes weeks, due to lymphocyte activation 3. It takes days, due to sensitized lymphocytes 4. takes minutes or hours, for preformed antibodies ## Question 27 Match with hapteno, paratope, epitope, antigen 1. substance that when combined with another can create an immune response 2. portion of the antibody that binds to the antigen 3. portion of the antigen that activates the antibody 4. substance that stimulates the production of specific antibodies ## Question 28 Match lymphocytes, eosinophils, neutrophils, natural killer cell, monocytes, basophils, macrophages, immature B lymphocyte, mast cell 1. regulate immunity through antibodies and cytokines 2. effective to combat allergies and parasites 3. first in diapedesis and phagocytosis 4. effective in killing cancer cells 5. produce type I interferon 6. IgE, allergies 7. Kupffer cells 8. IgD 9. basophils in tissue ## Question 29 Match with, gel and coombs type I reaction, gel and coombs type II reaction, gel and coombs type III reaction, gel and coombs type IV reaction 1. Release of histamines, leukotrins and prostaglandins that cause inflammation and rash. Bronchial asthma, rhinitis and allergic conjunctivitis. Excessive production of IgE in the presence of mites. Produces anaphylactic shock. Mast cell degranulation in case of allergies 2. Rejection reaction due to wrong transfusion. Cytotoxic disease due to excess IgM. Exogenous hapten produces hemolytic anemia or thrombocytopenia 3. Disease due to excess IgG in the serum causing inflammatory damage to the capillaries. Serum sickness, Arthus reaction and lupus erythematosus 4. Contact dermatitis due to T lymphocytes. Granuloma forms. ## Question 30 Match: pentamer, more effective in agglutination and lysis. First to form in the fetus. / Effective against viruses in mucous membranes.Dimer present in secretions. / Crosses the placenta. Most abundant in humanserum. / (IgG, IgM, IgA, IgD, IgE) 4. Matures B lymphocytes 5. Intervenes in allergic reactions. Present in mast cell and basophil membranes. ## Question 31 Match Id Structure The structure of immunoglobulin G A B C D E F G 1. Region where the antibody binds to the antigen 2. light chain 3. Where it joins the complement 4. heavy chain 5. Portion Fc 6. Fab Fragment 7. disulfide bond