Genetics Questions PDF

## Genetics Questions ### Question Text | Question Type | Points ------- | -------- | -------- Which type of mutation is characterized by the substitution of a single amino acid with another? | Multiple Choice| 1 Which of the following statements best describes the role of genetic mutations in the...

## Genetics Questions ### Question Text | Question Type | Points ------- | -------- | -------- Which type of mutation is characterized by the substitution of a single amino acid with another? | Multiple Choice| 1 Which of the following statements best describes the role of genetic mutations in the development of inherited diseases? | Multiple Choice | 1 Which of the following inheritance patterns is characteristic of autosomal dominant inheritance? | Multiple Choice | 1 Which of the following statements accurately describes autosomal dominant inheritance? | Multiple Choice | 1 Which of the following is an example of a chromosomal abnormality in the context of genetic disorders? | Multiple Choice | 1 In the context of genetic disorders, what does "penetrance" refer to? | Multiple Choice | 1 What is the term used to describe the complete set of genetic anomaly in the organism? | Multiple Choice | 1 Which of the following genetic disorders is characterized by an abnormality in the number of sex chromosomes? | Multiple Choice | 1 Which of the following inheritance patterns is characteristic of X-linked recessive inheritance? | Multiple Choice | 1 What is the term used to a change in a DNA sequence? | Multiple Choice | 1 What is the probability of having a child with a genetic disorder if both parents are carriers of an autosomal recessive disorder? | Multiple Choice | 1 Which of the following genetic disorders is caused by a mutation in the HTT gene? | Multiple Choice | 1 What is the term used to describe a pair of genes that are located at the same position on homologous chromosomes? | Multiple Choice | 1 What is the term used to describe an individual who has one copy of a mutated gene but does not show signs or symptoms of the associated disorder? | Multiple Choice | 1 Which of the following is an example of a multifactorial genetic disorder? | Multiple Choice | 1 Which of the following genetic disorders is caused by a mutation in the FMR1 gene? | Multiple Choice | 1 Which of the following is an example of a polygenic trait? | Multiple Choice | 1 Which of the following is an example of an X-linked recessive trait? | Multiple Choice | 1 Which of the following statements about genetic inheritance is incorrect? | Multiple Choice | 1 Which type of genetic disorder requires the presence of two copies of a mutated gene? | Multiple Choice| 1 Which type of genetic disorder is caused by a mutation in a normal human chromosome? | Multiple Choice | 1 What is the normal human chromosome diploid number? | Multiple Choice| 1 In DNA adenine normally pairs with? | Multiple Choice | 1 Genetic testing can provide information about? | Multiple Choice | 1 Which of the following is true about genetic disorders? | Multiple Choice | 1 What does a genotype refer to? | Multiple Choice | 1 Which of the following is an important factor in assessing genetic risks? | Multiple Choice | 1 What is the term for a genetic disorder caused by a mutation on the sex chromosomes? | Multiple Choice | 1 Which of the following best describes a mutation? | Multiple Choice | 1 Which of the following genetic disorders is caused by a trisomy of chromosome 21? | Multiple Choice | 1 What is the inheritance pattern of Duchenne muscular dystrophy? | Multiple Choice | 1 Which of the following is an example of a polygenic trait? | Multiple Choice | 1 Which of the following is an example of an X-linked recessive trait? | Multiple Choice | 1 Which of the following genetic disorders is characterized by a deletion in the gene that codes for dystrophin? | Multiple Choice | 1 What is the term used to describe a pair of genes that are located at the same position on homologous chromosomes? | Multiple Choice | 1 In the context of genetic disorders, what does "penetrance" refer to? | Multiple Choice | 1 The term phenotype can be applied to a wide range of manifestations. Which of the following properties, if any, do not constitute a phenotypic manifestation? | Multiple Choice | 1 Which, if any, of the following is incorrect? When used in human genetics, the term phenotype can be applied to a wide range of manifestations. | Multiple Choice | 1 Which, if any, of the following is incorrect? When used in human genetics, the term phenotype can be applied to a wide range of manifestations. | Multiple Answers | 1 Which, if any, of the following is incorrect? When used in human genetics, the term phenotype can be applied to a wide range of manifestations. | Multiple Answers | 1 Which, if any, of the following is incorrect? When used in human genetics, the term phenotype can be applied to a wide range of manifestations. | Multiple Choice | 1 With respect to autosomal dominant inheritance in humans, which, if any, of the following statements is incorrect? | Multiple Answers | 1 With respect to autosomal recessive inheritance, which, if any, of the following statements is incorrect? | Multiple Choice | 1 With respect to X-chromosome inactivation in females, which, if any, of the following statements is incorrect? | Multiple Choice | 1 With respect to X-linked recessive inheritance , which, if any, of the following statements is incorrect? | Multiple Choice | 1 With respect to X-linked dominant inheritance, which, if any, of the following statements is incorrect? | Multiple Choice | 1 With respect to mosaicism, which, if any, of the following statements is incorrect? | Multiple Choice | 1 An individual single gene disorder can show different levels of phenotypic expression. Which, if any, of the following statements is incorrect? | Multiple Answers | 1 The term phenotype can be applied to a wide range of manifestations. Which, if any, of the following statements is incorrect? | Multiple Choice | 1 Which, if any, of the following is incorrect? When used in human genetics, the term phenotype can be applied to a wide range of manifestations. | Multiple Answers | 1 Which, if any, of the following is incorrect? When used in human genetics, the term phenotype can be applied to a wide range of manifestations. | Multiple Answers| 1 Which, if any, of the following is incorrect? When used in human genetics, the term phenotype can be applied to a wide range of manifestations. | Multiple Choice | 1 With respect to autosomal dominant inheritance in humans, which, if any, of the following statements is incorrect? | Multiple Answers | 1 With respect to autosomal recessive inheritance, which, if any, of the following statements is incorrect? | Multiple Choice | 1 With respect to X-chromosome inactivation in females, which, if any, of the following statements is incorrect? | Multiple Choice | 1 With respect to X-linked recessive inheritance, which, if any, of the following statements is incorrect? | Multiple Choice | 1 With respect to X-linked dominant inheritance, which, if any, of the following statements is incorrect? | Multiple Choice | 1 With respect to mosaicism, which, if any, of the following statements is incorrect? | Multiple Choice | 1 An individual single gene disorder can show different levels of phenotypic expression. Which, if any, of the following statements is incorrect? | Multiple Answers | 1 Choose the disease due to unstable repeat expansions | Multiple Choice | 1 In DNA adenine normally pairs with | Multiple Choice | 1 Which of the following is not characteristic of the inheritance pattern of autosomal dominant disorders? | Multiple Choice | 1 Which is true of newborn screening tests for genetic disorders? | Multiple Choice | 1 Which of the following statements about the role of genetic mutations in the development of inherited diseases is incorrect? | Multiple Choice | 1 The idea that different pairs of alleles are passed to offspring during gamete formation is known as? | Multiple Choice | 1 Characteristics of women with Turner's syndrome include | Multiple Choice | 1 Which of the following enzymatic steps is the rate-limiting step in the synthesis of purine nucleotides? | Multiple Choice | 1 What is the normal human chromosome diploid number? | Multiple Choice | 1 Which of the following patients has the highest risk of developing childhood cancers? | Multiple Choice | 1 Which syndrome is according to isochromosome existing? | Multiple Choice | 1 Which syndrome is monosomy is, Where the individual is born with one copy less of chromosome 18? | Multiple Choice | 1 Which karyotype is Edwards Syndrome's? | Multiple Choice | 1 Which staining is used to the diagnosis of Cytogenetic disorders? | Multiple Choice | 1 A chromosome entering meiosis is composed of two chromatids | Multiple Choice | 1 The enzyme adenosine deaminase (ADA) is important for the synthesis of what molecule? | Multiple Choice | 1 Interleukin-10 (IL-10) is known for its role in? | Multiple Choice | 1 During the process of rolling adhesion, neutrophils initially bind to what type of molecules? | Multiple Choice | 1 Which statement best describes xanthine? | Multiple Choice | 1 Choose the correct statement | Multiple Choice | 1 Which of the following is correct? When used in human genetics, the term "penetrance" refers to? | Multiple Choice | 1 X chromosome inactivation is a mechanism for which of the following processes? | Multiple Choice | 1 The purine nucleotide salvage pathway involves the synthesis of what molecule? | Multiple Choice | 1 Which of the following X-linked disease has homozygous females rarely affected? | Multiple Choice | 1 Which of the following disease is a good example of allelic heterogeneity? | Multiple Choice | 1 Choose the disease due to unstable repeat expansions. | Multiple Choice | 1 Choose the incorrect statement: For every base pair there is a corresponding pair of nitrogenous bases. | Multiple Choice | 1 **Answer 1** | **Answer 2** | **Answer 3** ------- | -------- | -------- Frameshift mutation | Reverse mutation | Nonsense mutation A) Genetic mutations are always harmful and cause all inherited diseases. | B) Genetic mutations have no impact on the development of inherited diseases. | [Y]c)Genetic Mutations can either be harmful or have no significant effect on the development of inherited diseases [Y]A) The disorder primarily affects females | B) The disorder is passed on from father to son | [Y]c) The Disorder affects males more A) The disorder primarily affects females | B) The disorder is passed on from father to son | C) The disorder requires both parents to be carriers. A) Cystic fibrosis | [Y]B) Down Syndrome | C) Huntington's disease A) The likelihood of passing on a genetic disorder to the next generation. | B) The severity of symptoms experienced by individuals affected by a genetic disorder | C) The age at which symptoms of a genetic disorder typically manifest. A) Genotype | B) Phenotype | C) Chromosome [Y]A) Turner Syndrome | B) Marfan syndrome | C) Cystic fibrosis A) Autosomal recessive | B) Autosomal dominant | C) X-linked recessive A) PolyMorphism | [Y] Mutation | C) Deletion A) 75% | B) Cystic fibrosis | [Y]c) 25% [Y]A) Huntington's Disease | B) Cystic fibrosis | C) Down syndrome A) Homozygous | B) Heterozygous | [Y]c) Locus A) Homozygous | B) Heterozygous | [Y] c) Carrier A) Huntington's disease | B) Sickle cell anemia | [Y]C) Cleft Lip and palate A) Duchenne muscular dystrophy | [Y]B) Fragile X Syndrome | C) Down syndrome A) Cystic fibrosis | B) Sickle cell anemia | [Y]c) Height A)Down syndrome | B) Marfan syndrome | [Y]c) HemoPhilia A) In autosomal dominant inheritance, the disorder is caused by a mutation in a single gene. | [Y]B) A Carrier Of a recessive genetic disorder | C) Incomplete dominance occurs when the recessive allele is expressed | A) Autosomal dominant disorder | [Y] B) Autosomal Recessive disorder | C) X-linked dominant disorder A) Multifactorial disorder | B) Chromosomal disorder | C) Autosomal recessive disorder A. 23 | B. 24 | [Y] c. 46 [Y]A. Thymine | B. guanine | C. cytosine a) An individual's genetic ancestry. | b) An individual's risk for developing a genetic disorder | c) Whether a person will have a genetic disorder. a) They are always caused by mutations in multiple genes. | b) They are always caused by mutations in a single gene. | [Y]c) They Can be caused by mutations in a single gene or multiple genes a) The physical traits or characteristics of an individual. | [Y]b) The Genetic makeup or alleles an individual carries | c) The Presence of a mutation in a gene. a) Environmental factors. | [Y]b) Family Medical history | c) Blood Type. a) Autosomal dominant disorder | [Y]b) X-Linked Recessive disorder | c) Y-linked disorder [Y] a) A Change In the sequence of DNA | b) A change in the structure of a chromosome | c) A change in the function of a protein a) Turner syndrome | [Y] b) Down Syndrome | c) Klinefelter syndrome a) Autosomal dominant | b) Autosomal recessive | c) X-linked dominant A) cystic fibrosis | B) sickle cell anemia | [Y]c) Height [Y] HemoPhilia | Marfan syndrome | Down syndrome [Y] Turner Syndrome | Marfan syndrome | Cystic fibrosis **Answer 4** | **Answer 5** | **Answer 6** ------- | -------- | -------- [Y]Missense Mutation | | D) Genetic mutations only affect non-inherited diseases. | | D) The disorder is equally prevalent in affected and unaffected individuals. | [Y]D) The Disorder is passed on from an affected parent to approximately half of their offspring | D) Duchenne muscular dystrophy | | [Y]D) The Percentage of individuals with a specific genetic mutation who exhibit symptoms of the associated disorder | | [Y]Genome | | D) Sickle cell anemia | | [Y]D) Maternal Inheritance | | D) Duplication | | D) 100% | | D) Hemophilia | | D) Allele | | D) Phenotype | | D) Duchenne muscular dystrophy | | D) Cystic fibrosis | | D) Huntington's disease | | D) Turner syndrome | | D) Genetic disorders caused by X-linked recessive disorder | [Y]D) Monogenic Disorder | [Y]D) All Of the above | | d) They are never caused by genetic mutations | | d) The observable expression of a gene | | d) Height and weight | | d) Mitochondrial disorder | | d) A change in the number of chromosomes | | d) Fragile X syndrome | | [Y]d) X-Linked Recessive | | D) huntington's disease | | Turner syndrome | | Sickle cell anemia | | [Y}LOCUS | | [Y]The Percentage of individuals with a specific genetic mutation who exhibit symptoms of the associated disorder | | d) autistic behavior | | d) implies a phenotypic feature that is not easily observable. | | [Y] d) Does Not apply to loci on the X | | d) does not apply to loci in the | | d) the AB blood group is an example of a Mendelian trait. | | [Y] The Term dominant applies equally to alleles on the X and Y chromosome. | | D) Some affected individuals have alleles that are not expressed. | | D) Once the decision is made to inactivate an X chromosome in a cell, all descendant cells will continue with that pattern of X-inactivation. | | D) Each child born to a normal man and a woman will inherit both a maternal and paternal X chromosome. | | D) Each boy born to an affected father has a 50% chance of inheriting the affected allele | | [Y] d) Mosaicism Is the inevitable | | D) The situation where different mutations result in the same phenotype | | [Y} D)The Sequence of a person's beta globin gene | | D)implies a phenotypic feature that is not easily observable. | | [Y]D)Describes Any individual gene variant | | D)applies even if a person possesses two alleles for the same gene. | | D)does not apply to loci in the | | D)the AB blood group is an example of a Mendelian trait. | | [Y]D)The Term dominant applies equally to alleles on the X and Y chromosome. | | D) Some affected individuals have alleles that are not expressed. | | D)Once the decision is made to inactivate a paternal X or the maternal X in a cell, all descendant cells will continue with that pattern of X-inactivation. | | D)Each child born to a normal man and a woman will inherit both a maternal and paternal X chromosome. | | D)Each boy born to an affected father has a 50% chance of inheriting the affected allele | | D)Every person is a genetic mosaic. | | D)The situation where different mutations result in the same phenotype | | [Y]D)Huntington Disease (HD) | | D)Uracil | | D)maternal inheritance | | [Y]D)Which Are treatable and/or preventable | | [Y]D)Glutamate Dehydrogenase | | D)Segregation | | [Y]D)The almost always display short stature | | D)Porphobilinogen deaminase | | D)48 | | D)18-year-old college freshman with iron deficiency anemia | | D)Wolf-hirschone syndrome | | [Y]D)Turner Syndrome | | D) Trisomy X-Chromome's syndrome | | D)None of them | | D) None of them. | | D)Orotic aciduria | | D)Enhancing cytotoxic T cel activity | | D)cytokines | | D)it is a direct precursor of guanine | | [Y]D)DZ Twins are of the same sex half the time | | D)does not apply to loci on the X | | D)Elimination of deleterious genes from the population | | D)Adenine phosphoribosyltransferase | | D)Dyschondrosteosis | | D)Hemochromatosis | | D)Neurofibromatosis | | [Y]D)Four Frameshift | |