Endocrine 1 PDF
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University of the Incarnate Word
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Summary
This document provides a table of endocrine drugs, categorized by various pharmacological factors, along with their generic names, brand names, common indications, essential knowledge, and key side effects. It also shows US box warnings, which are critical to understand drug safety.
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ENDOCRINE 1 Pharmacologic Category Generic Name Brand Name Common Indications Essential Knowledge Glucophage, Key Side Effects:...
ENDOCRINE 1 Pharmacologic Category Generic Name Brand Name Common Indications Essential Knowledge Glucophage, Key Side Effects: diarrhea, nausea, vomiting Biguanide metformin (PO) Glucophage Type 2 DM, PCOS US Boxed Warnings: lactic acidosis XR Dipeptidyl peptidase Januvia, sitagliptin (PO) Type 2 DM Key Side Effects: headache, nasopharyngitis (DPP-4) inhibitor Zituvio Sodium-glucose cotransporter inhibitor 2 empagliflozin (PO) Jardiance Type 2 DM, HF Key Side Effects: UTI (SGLT2 inhibitor) glimepiride (PO) Amaryl Glucotrol, Sulfonylurea glipizide (PO) Type 2 DM Key Side Effects: hypoglycemia, weight gain Glucotrol XL glyburide (PO) Glynase Key Side Effects: edema, weight gain, upper respiratory tract infection Thiazolidinedione (TZD) pioglitazone (PO) Actos Type 2 DM US Boxed Warnings: may exacerbate congestive heart failure and CI in NYHA Class III and IV Glucagon-like peptide-1 Victoza, Type 2 DM, chronic Key Side Effects: nausea, vomiting, diarrhea, constipation liraglutide (SQ) (GLP-1) receptor agonist Saxenda weight management US Boxed Warnings: may increase risk of thyroid c-cell tumor Lantus, Insulin, long acting insulin glargine (SQ) Toujeo, Basaglar Insulin, intermediate Humulin N, Type 1 DM, type 2 DM insulin NPH (SQ) acting Novolin N Key Side Effects: hypoglycemia, weight gain insulin aspart (SQ) Novolog Insulin, rapid acting insulin lispro (SQ) Humalog insulin regular Humulin R, Type 1 DM, type 2 Insulin, short-acting (SQ, IV) Novolin R DM, DKA levothyroxine (PO, Synthroid, Key Side Effects: weight loss, palpitations, diarrhea, insomnia, heat intolerance IV) Levoxyl US Boxed Warnings: not intended for use for weight loss Thyroid product Hypothyroidism thyroid, dessicated Armour Other Notes: narrow therapeutic index drug (therapeutic monitoring is (PO) Thyroid recommended); not all generic products are therapeutically equivalent See individual drug sitagliptin and Janumet,. components metformin (PO) Janumet XR See individual drug components DKA: diabetic ketoacidosis; DM: diabetes mellitus; PCOS: polycystic ovarian syndrome; UTI: urinary tract infection
