Drugs of Abuse PDF

Drugs of Abuse Drug Intoxication Withdrawal Alcohol benzodiazepines Disinhibition, mood Tremulousness, lability, incoordination, hypertension, slurred speech, ataxia, tachycard...

Drugs of Abuse Drug Intoxication Withdrawal Alcohol benzodiazepines Disinhibition, mood Tremulousness, lability, incoordination, hypertension, slurred speech, ataxia, tachycardia, anxiety, blackouts (EtOH), psychomotor respiratory agitation, nausea, depression seizures, hallucinations, DTs (EtOH) Barbiturates Respiratory depression Anxiety, seizures, delirium, life-threatening cardiovascular collapse Opioids CNS depression, nausea, Increased sympathetic vomiting, activity, sedation, decreased pain N/V, diarrhea, perception, decreased GI diaphoresis, rhinorrhea, motility, piloerection, yawning, pupil constriction, stomach respiratory cramps, myalgias, depression arthralgias, restlessness, anxiety, anorexia Amphetamines Euphoria, increased Post-use “crash”: cocaine attention restlessness, span, aggressiveness, headache, hunger, severe psychomotor depression, irritability, agitation, pupil dilatation, insomnia/ hypertension, hypersomnia, strong tachycardia, psychological craving cardiac arrhythmias, psychosis, formication with cocaine PCP Belligerence, May have recurrence of impulsiveness, symptoms psychomotor due to reabsorption in GI agitation, tract vertical/horizontal nystagmus, hyperthermia, tachycardia, ataxia, psychosis, homicidality LSD Altered perceptual states (hallucinations, distortions of time and space), elevation of mood, “bad trips” (panic reaction), flashbacks (reexperience of the sensations in absence of drug use) Cannabis Euphoria, anxiety, paranoia, slowed time, social withdrawal, increased appetite, dry mouth, tachycardia, amotivational syndrome Nicotine/ Restlessness, insomnia, Irritability, lethargy, Caffeine anxiety, headache, anorexia increased appetite, weight gain First Aid for the Psychiatry Clerkship, 4e; copyright © 2015 McGraw-Hill. All rights reserved