Structures and Functions of the Visual System PDF

Summary

This document provides an overview of the visual system, explaining its key components, protective structures, and functions. It also touches on the assessment of the visual system, including subjective and objective data collection. The document uses clear definitions of anatomical structures and functions.

Full Transcript

👁️‍🗨️ Structures and Functions of the Visual System The Visual System: An Overview Definition: The visual system is a complex network encompassing the eyes (image receptors) and the brain (image processing and interpretation center), both integral parts of the central nervous system. Key Componen...

👁️‍🗨️ Structures and Functions of the Visual System The Visual System: An Overview Definition: The visual system is a complex network encompassing the eyes (image receptors) and the brain (image processing and interpretation center), both integral parts of the central nervous system. Key Components: Eyes: Capture light and convert it into neural signals. Optic Nerve: Transmits signals from the eyes to the brain. Brain (Visual Cortex): Processes and interprets signals to create visual perception. Advanced Concepts: The visual pathway involves multiple brain regions beyond the visual cortex, each contributing to specific aspects of visual processing (e.g., motion detection, object recognition, depth perception). Understanding the specific roles of these areas is crucial for diagnosing and managing complex visual disorders. Protective Structures of the Eye Definition: Several structures safeguard the eye from external threats. Key Structures: Eyebrows: Shield the eyes from sweat and debris. Eyelids: Protect the eyes from foreign bodies and excessive light. Eyelashes: Trap dust and other particles. Lacrimal System: Produces and drains tears, lubricating and cleansing the eye. This system includes the lacrimal gland (tear production), lacrimal ducts (tear drainage), and nasolacrimal duct (drains tears into the nasal cavity). Advanced Concepts: The lacrimal system's composition (e.g., lysozyme, immunoglobulins) and its role in immune defense against pathogens are important considerations in eye disease. Layers of the Eyeball Definition: The eyeball (globe) has three distinct layers. Key Layers: Outer Layer (Fibrous Tunic): Includes the cornea (transparent, allows light entry), sclera (white, protective outer layer), and conjunctiva (mucous membrane lining the eyelids and covering the sclera). Middle Layer (Uveal Tract): Consists of the iris (controls pupil size), ciliary body (focuses the lens), and choroid (provides blood supply to the retina). Inner Layer (Retina): Contains photoreceptor cells (rods for low-light vision, cones for color vision) that convert light into neural signals. Advanced Concepts: Understanding the detailed cellular structure of the retina (photoreceptor cells, bipolar cells, ganglion cells) and their interconnections is essential for comprehending retinal diseases. Anterior and Posterior Cavities Definition: The anterior segment of the eye is divided into two chambers. Key Cavities: Anterior Chamber: Between the cornea and iris, filled with aqueous humor (nourishes the cornea and lens). Posterior Chamber: Between the iris and lens, also filled with aqueous humor. Posterior Cavity (Vitreous Chamber): Larger cavity behind the lens, filled with vitreous humor (supports the retina). Advanced Concepts: The dynamics of aqueous humor production and drainage are critical in understanding glaucoma. Changes in vitreous humor with age can contribute to retinal detachment. Lens and Pupil Function Definition: The lens and pupil play crucial roles in focusing light onto the retina. Key Functions: Lens: Changes shape (accommodation) to focus light on the retina at varying distances. This process is controlled by the ciliary muscle. Pupil: The opening in the iris that regulates the amount of light entering the eye. Pupillary constriction (miosis) is mediated by the iris sphincter muscle, while pupillary dilation (mydriasis) is mediated by the iris dilator muscle. Advanced Concepts: Presbyopia (age-related loss of accommodation) and various pupillary reflexes (e.g., light reflex, accommodation reflex) are important clinical considerations. 🔎 Assessment of the Visual System Subjective Data Collection Definition: Gathering information directly from the patient about their visual experiences. Key Aspects: Ocular History: Past eye problems, surgeries, injuries, and family history of eye diseases. Medical History: Systemic diseases (e.g., diabetes, hypertension) and medications that can affect vision. Visual Symptoms: Changes in vision (blurriness, double vision, floaters), pain, redness, discharge, etc. Functional Impact: How visual problems affect daily activities (reading, driving, work). Advanced Concepts: Understanding the correlation between systemic diseases and ocular manifestations is crucial for accurate diagnosis and management. Objective Data Collection: Visual Acuity and Tests Definition: Measuring and assessing visual function through various tests. Key Tests: Visual Acuity: Measures the sharpness of vision using Snellen chart (distance vision) and near vision charts (Jaeger card). 20/20 vision indicates normal acuity. Color Vision: Assesses the ability to distinguish colors using Ishihara plates. Extraocular Muscle Function: Evaluates eye movement using the six cardinal positions of gaze. Visual Fields: Determines the extent of peripheral vision using confrontation testing or perimetry. Pupil Function: Assesses pupil size, shape, and reactivity to light and accommodation. Intraocular Pressure (IOP): Measures the pressure inside the eye using tonometry (important for glaucoma detection). Stereopsis: Assesses depth perception. Advanced Concepts: Interpreting visual field defects can help localize lesions in the visual pathway. Understanding the different types of tonometry and their limitations is important. Objective Data Collection: Visual Structure Assessment Definition: Examining the external and internal structures of the eye. Key Aspects: Inspection: Assessing the external structures (eyebrows, eyelids, eyelashes, conjunctiva, sclera) for abnormalities. Ophthalmoscopy: Using an ophthalmoscope to visualize the internal structures (retina, optic disc, blood vessels). Advanced Concepts: Recognizing subtle changes in the retina (e.g., hemorrhages, exudates) and optic disc (e.g., pallor, swelling) is crucial for diagnosing various eye diseases. 🔬 Diagnostic Studies of the Visual System Refractometry Definition: Measures the refractive error of the eye (myopia, hyperopia, astigmatism) to determine the need for corrective lenses. Key Aspects: This involves using a phoropter to assess the patient's refractive error and determine the appropriate lens prescription. Advanced Concepts: Understanding different types of refractive errors (myopia, hyperopia, astigmatism, presbyopia) and their underlying causes is essential. Ultrasound Definition: Uses sound waves to create images of the eye's internal structures, particularly useful when the eye is opaque. Key Applications: Evaluating conditions like retinal detachment, tumors, and foreign bodies. Advanced Concepts: Different ultrasound techniques (A-scan, B-scan) provide different types of information. Fluorescein Angiography Definition: Involves injecting fluorescein dye into a vein and taking photographs of the eye to visualize blood vessels in the retina and choroid. Key Applications: Diagnosing and monitoring conditions like macular degeneration, diabetic retinopathy, and retinal vascular occlusions. Advanced Concepts: Interpreting the angiographic images requires specialized knowledge. Amsler Grid Test Definition: A simple test used to detect distortions in central vision, particularly helpful in detecting macular degeneration. Key Aspects: The patient looks at a grid and reports any distortions or blind spots. Advanced Concepts: Understanding the patterns of visual field loss associated with different macular diseases is important. Perimetry (Visual Field Testing) Definition: Measures the extent of a patient's peripheral vision. Key Applications: Detecting and monitoring glaucoma, stroke, and other neurological conditions affecting the visual pathway. Advanced Concepts: Different types of perimetry (kinetic, static) provide different information. Interpreting perimetric results requires specialized knowledge. 👓 Visual Problems: Refractive Errors and Visual Impairment Refractive Errors Definition: Conditions where light rays do not focus properly on the retina, leading to blurred vision. Types: Myopia (Nearsightedness): Difficulty seeing distant objects. Hyperopia (Farsightedness): Difficulty seeing near objects. Presbyopia: Age-related loss of accommodation (ability to focus on near objects). Astigmatism: Irregular corneal curvature causing blurred vision at all distances. Advanced Concepts: Understanding the mechanisms of refractive errors (axial length, corneal curvature) and the principles of corrective lenses is important. Visual Impairment Definition: A broad term encompassing conditions ranging from low vision to total blindness. Key Aspects: Low Vision: Significant visual impairment that cannot be corrected with glasses or contact lenses. Legal Blindness: Best-corrected visual acuity of 20/200 or worse in the better eye, or a visual field of 20 degrees or less. Advanced Concepts: The impact of visual impairment on daily living and the various assistive devices available are important considerations. 🤕 Extraocular and Intraocular Disorders This section will cover a wide range of disorders affecting the eye, categorized for clarity. Due to the extensive nature of the material, only key features and treatment approaches will be highlighted. Consult the original text for complete details. Extraocular Disorders: Inflammation and Infection Hordeolum (Sty): Infection of sebaceous glands in the eyelid. Chalazion: Chronic inflammatory granuloma of meibomian glands. Blepharitis: Chronic inflammation of eyelid margins. Conjunctivitis (Pinkeye): Infection or inflammation of the conjunctiva. Bacterial conjunctivitis is often self-limiting but may be treated with antibiotic drops. Trachoma is a chronic form caused by Chlamydia trachomatis. Keratitis: Corneal inflammation or infection (bacterial, viral, fungal). Treatment is aggressive to prevent vision loss. Extraocular Disorders: Noninfectious Disorders Keratoconjunctivitis Sicca (Dry Eyes): Decreased tear production. Strabismus: Misalignment of the eyes. Corneal Wounds/Keratoconus: Corneal damage or cone-shaped cornea. May be corrected with lenses or surgery. Corneal transplants may be necessary. Intraocular Disorders: Cataracts Definition: Opacity of the lens, leading to decreased vision, abnormal color perception, and glare. Treatment: Surgical removal with intraocular lens implantation. Postoperative Care: Eye care, activity restrictions, medication, and monitoring for complications. Intraocular Disorders: Retinopathy Definition: Microvascular damage to the retina, often associated with diabetes and hypertension. Types: Nonproliferative Diabetic Retinopathy: Capillary microaneurysms, retinal swelling, hard exudates. May be treated with laser photocoagulation. Hypertensive Retinopathy: Retinal hemorrhages, macular swelling. Treatment focuses on lowering blood pressure. Intraocular Disorders: Retinal Detachment Definition: Separation of the retina from the underlying epithelium. Causes: Retinal breaks (tears or holes). Symptoms: Light flashes, floaters, rings in vision, painless vision loss. Treatment: Surgical repair (laser photocoagulation, cryopexy, scleral buckling). Intraocular Disorders: Age-Related Macular Degeneration (AMD) Definition: Leading cause of irreversible central vision loss in older adults. Types: Dry (Nonexudative) AMD: Atrophy of macular cells, slow vision loss. Wet (Exudative) AMD: Abnormal blood vessel growth, rapid vision loss. Treatment: Laser photocoagulation, photodynamic therapy, intravitreous injections, vitamin/mineral supplements. Intraocular Disorders: Glaucoma Definition: Group of disorders characterized by increased intraocular pressure (IOP), optic nerve atrophy, and peripheral visual field loss. Types: Primary Open-Angle Glaucoma (POAG): Decreased outflow of aqueous humor. Few symptoms until late stages. Primary Angle-Closure Glaucoma (PACG): Sudden, severe eye pain, nausea, vomiting. Treatment: Medications, laser trabeculoplasty, trabeculectomy, iridotomy. Intraocular Disorders: Intraocular Inflammation and Infection Uveitis: Inflammation of the uveal tract. Cytomegalovirus (CMV) Retinitis: Opportunistic infection in immunosuppressed patients. Endophthalmitis: Inflammation of the vitreous cavity. Treatment: Antimicrobial or anti-inflammatory agents. Intraocular Disorders: Ocular Tumors Definition: Benign or cancerous tumors of the eye. Treatment: Radiation therapy, photocoagulation, surgery (resection, enucleation). Enucleation Definition: Surgical removal of the eye. Indications: Ocular cancer, trauma, infection, glaucoma. Postoperative Care: Prosthesis fitting. 👂 Auditory Problems (Chapter 23 Overview) This section provides a concise overview of auditory problems based on the provided text. Due to space constraints, detailed explanations of each condition are omitted. Refer to the original text for complete information. Auditory System Anatomy and Physiology The auditory system comprises peripheral (external, middle, inner ear) and central (brain) components. Conductive hearing loss results from outer or middle ear problems. Sensorineural hearing loss stems from inner ear or nerve pathway issues. Central hearing loss involves the brain's processing of auditory information. Sound is measured in decibels (dB) and hertz (Hz). The vestibular apparatus in the inner ear is crucial for balance. Presbycusis is age-related hearing loss. Tinnitus is ringing in the ears. Assessment of the Auditory System A thorough health history is essential, including past illnesses, medications, trauma, and auditory tests. Functional assessment evaluates the impact of hearing loss on daily life. Physical assessment includes inspection of external ear structures and otoscopic examination of the tympanic membrane and ear canal. Diagnostic Studies Audiometry provides detailed hearing information. Tuning fork tests differentiate conductive and sensorineural hearing loss. CT and MRI scans detect lesions. External Ear and Canal Disorders External otitis (infection), cerumen impaction, and foreign bodies are common problems. Malignancy of the external ear is less frequent. Middle Ear and Mastoid Disorders Acute otitis media (infection), chronic otitis media, mastoiditis, and otosclerosis (abnormal bone growth) are significant middle ear conditions. Inner Ear Problems Ménière's disease (inner ear fluid imbalance), benign paroxysmal positional vertigo (debris in semicircular canals), and acoustic neuroma (vestibulocochlear nerve tumor) are inner ear disorders. Hearing Loss and Deafness Conductive and sensorineural hearing loss have different causes and management strategies. Assistive devices (hearing aids, cochlear implants) and techniques (speech reading, sign language) are available. Tinnitus is a common symptom. Noise-induced hearing loss is preventable. Presbycusis is age-related hearing loss. 🩸 Hematologic System (Chapter 33 & 34 Overview) This section provides a concise overview of the hematologic system and related problems. Due to the extensive nature of the material, only key features and treatment approaches will be highlighted. Consult the original text for complete details. Structures and Functions of the Hematologic System Hematology encompasses the study of blood and blood-forming tissues (bone marrow, spleen, lymph system). Hematopoiesis (blood cell production) occurs in the bone marrow. Blood has three major functions: transportation, regulation, and protection. Blood consists of plasma and blood cells (erythrocytes, leukocytes, thrombocytes). Hemoglobin (in RBCs) carries oxygen and carbon dioxide. Leukocytes (WBCs) have various immune functions (granulocytes, lymphocytes, monocytes). Thrombocytes (platelets) initiate clotting. Hemostasis is the blood clotting process. The spleen plays roles in hematopoiesis, filtration, immunity, and storage. The lymph system carries fluid from tissues to the blood. Gerontologic Considerations Hemoglobin levels may decrease in older men. RBC osmotic fragility increases. WBC counts generally remain stable, but immune function may decline. Assessment of the Hematologic System Health history includes demographic data, current health status, past medical history, medications, surgeries, family history, and review of systems. Physical examination assesses lymph nodes, liver, spleen, and skin. Diagnostic Studies Complete blood count (CBC), differential WBC count, erythrocyte sedimentation rate (ESR), iron metabolism tests (serum iron, TIBC, ferritin, transferrin saturation), radiologic studies (CT, PET, MRI), bone marrow examination, lumbar puncture, lymph node biopsy, and tests for cell surface markers and genetic variations are used for diagnosis. Anemia Anemia is a deficiency of erythrocytes, hemoglobin, or hematocrit. Types are classified by morphology and etiology. Clinical manifestations result from tissue hypoxia. Interventions include blood transfusions, drug therapy, volume replacement, oxygen therapy, dietary modifications, and lifestyle changes. Causes of Anemia: Decreased erythrocyte production (iron-deficiency, thalassemia, megaloblastic anemias, anemia of chronic disease, aplastic anemia), blood loss (acute, chronic), increased erythrocyte destruction (sickle cell disease, acquired hemolytic anemia). Hemochromatosis and Polycythemia Hemochromatosis involves increased iron absorption and deposition. Polycythemia is increased RBC production. Problems of Hemostasis Thrombocytopenia (low platelet count), hemophilia (coagulation factor deficiency), von Willebrand disease (von Willebrand factor deficiency), disseminated intravascular coagulation (DIC), and neutropenia (low neutrophil count) are hemostasis disorders. Myelodysplastic Syndrome and Leukemia Myelodysplastic syndrome (MDS) involves changes in bone marrow elements. Leukemia is cancer of blood and blood-forming tissues. Types include acute lymphocytic leukemia (ALL), acute myelocytic leukemia (AML), chronic myelogenous leukemia (CML), and chronic lymphocytic leukemia (CLL). Treatment involves chemotherapy and hematopoietic stem cell transplantation. Lymphomas and Multiple Myeloma Lymphomas are cancers originating in lymphatic structures (Hodgkin's lymphoma, non- Hodgkin's lymphoma). Multiple myeloma involves cancerous plasma cells infiltrating the bone marrow. Disorders of the Spleen Splenomegaly (enlarged spleen) can lead to decreased circulating blood cells. Splenectomy may be necessary. Blood Component Therapy Blood component therapy provides temporary support. Autologous transfusion uses the patient's own blood. Transfusion reactions (acute and delayed) can occur. 🍔 Gastrointestinal System (Chapter 43, 44, 46, 47 Overview) This section provides a concise overview of the gastrointestinal system and related problems. Due to the extensive nature of the material, only key features and treatment approaches will be highlighted. Consult the original text for complete details. Structures and Functions of the Gastrointestinal System The GI system's main function is nutrient supply through ingestion, digestion, absorption, and elimination. The autonomic nervous system innervates the GI tract. The enteric nervous system regulates motility and secretion. GI movements include mixing (segmentation) and propulsion (peristalsis). GI secretions include enzymes, hormones, mucus, water, and electrolytes. Upper GI System The mouth, pharynx, and esophagus transport food to the stomach. The stomach stores, mixes, and empties food into the small intestine. Gastric secretions include HCl and intrinsic factor. The small intestine is the primary site of digestion and absorption. Lower GI System The large intestine absorbs water and electrolytes. It comprises the cecum, appendix, colon, rectum, and anus. Liver, Biliary Tract, and Pancreas The liver performs metabolic, secretory, vascular, and storage functions. The biliary tract includes the gallbladder and ducts. Bile aids digestion. The pancreas has exocrine (digestive enzymes) and endocrine (insulin, glucagon, somatostatin) functions. Gerontologic Considerations Aging affects GI function, including appetite, taste, smell, saliva production, liver size, and drug metabolism. Assessment of the Gastrointestinal System Subjective data includes abdominal pain, nausea, vomiting, diarrhea, constipation, jaundice, heartburn, dyspepsia, appetite changes, and bleeding. Objective data involves physical examination of the mouth, abdomen, and perianal area. Diagnostic Studies Upper GI series, lower GI series (barium enema), ultrasonography, virtual colonoscopy, endoscopy (ERCP), capsule endoscopy, liver biopsy, and liver function tests are used for diagnosis. Nutrition Problems Nutrition is essential for energy, growth, and tissue repair. Malnutrition can be undernutrition or overnutrition. Causes include socioeconomic factors, cultural influences, psychological disorders, medical conditions, and food-drug interactions. Malabsorption syndrome impairs nutrient absorption. Refeeding syndrome involves fluid retention and electrolyte imbalances. Enteral nutrition (EN) and parenteral nutrition (PN) provide nutritional support. Eating disorders (anorexia nervosa, bulimia nervosa) require specialized management. Obesity Obesity is a complex, multifactorial disease resulting from an energy imbalance. It increases the risk of various health problems. Management involves lifestyle changes (diet, exercise, behavior modification), drug therapy, and bariatric surgery. Metabolic syndrome is a cluster of risk factors for cardiovascular disease and diabetes. Upper Gastrointestinal Problems Nausea and vomiting are common symptoms of various GI disorders. Oral inflammations and infections can impair food intake. Oral cancer is a serious condition. Gastroesophageal reflux disease (GERD) involves reflux of gastric contents into the esophagus. Hiatal hernia is the herniation of the stomach into the esophagus. Esophageal cancer has various causes and treatments. Other esophageal disorders include diverticula and achalasia. Peptic Ulcer Disease (PUD) PUD involves erosion of the GI mucosa. Most cases are associated with H. pylori infection. Treatment includes antibiotics, proton pump inhibitors (PPIs), H2-receptor blockers, and lifestyle modifications. Complications include bleeding, perforation, and obstruction. Stomach Cancer and Gastric Surgery Stomach cancer often spreads before causing symptoms. Treatment depends on the stage of the disease. Gastric surgery (gastrectomy, vagotomy, pyloroplasty) can lead to complications like dumping syndrome and pernicious anemia. Gastritis is inflammation of the gastric mucosa. Upper GI bleeding requires prompt diagnosis and treatment. Foodborne illness is caused by contaminated food or liquids. E. coli O157:H7 poisoning is a serious form of foodborne illness. Lower Gastrointestinal Problems Diarrhea involves frequent loose stools. Causes include infections and other factors. Treatment focuses on fluid and electrolyte balance. Fecal incontinence is involuntary passage of stool. Constipation involves infrequent bowel movements. Acute abdominal pain requires prompt evaluation. Abdominal trauma (blunt, penetrating) can cause various injuries. Chronic abdominal pain has various causes. Irritable bowel syndrome (IBS) is a chronic disorder with abdominal pain and altered bowel patterns. Inflammatory Disorders Appendicitis (appendix inflammation), peritonitis (peritoneal inflammation), and gastroenteritis (stomach and small intestine inflammation) are inflammatory disorders. Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis. Treatment involves medications to control inflammation and surgery in severe cases. Bowel Obstruction Bowel obstruction can be partial or complete, simple or strangulated. Treatment depends on the type and severity of the obstruction. Polyps of the large intestine are growths that can become cancerous. Colorectal cancer (CRC) is a serious condition with various risk factors and treatments. Bowel resection and ostomy surgery may be necessary for various conditions. Fistulas are abnormal tracts between organs or an organ and the skin. Diverticulosis and diverticulitis involve outpouchings in the colon. Hernias are protrusions of a viscus through a weakened area. Malabsorption Syndrome Malabsorption involves impaired nutrient absorption. Causes include enzyme deficiencies, mucosal damage, and lymphatic/vascular problems. Celiac disease is an autoimmune disorder triggered by gluten. Lactase deficiency involves a lack of the lactase enzyme. Short bowel syndrome (SBS) results from the loss of small intestine. Gastrointestinal stromal tumors (GISTs) are rare cancers. Anorectal Problems Hemorrhoids are dilated hemorrhoidal veins. Anal fissures are tears in the anal mucosa. Anorectal abscesses are collections of pus. Anal fistulas are abnormal tunnels. Anal cancer is uncommon but serious. Pilonidal sinus is a tract under the skin between the buttocks. Important Facts to Memorize 1. Visual System: The visual system comprises the eyes (receptors) and the brain (processing center). 2. Protective Structures: Eyebrows, eyelids, eyelashes, and the lacrimal system protect the eye. 3. Eyeball Layers: The eyeball has three layers: fibrous tunic (cornea, sclera, conjunctiva), uveal tract (iris, ciliary body, choroid), and retina. 4. Anterior/Posterior Cavities: The anterior segment is divided into anterior and posterior chambers filled with aqueous humor; the posterior cavity contains vitreous humor. 5. Lens/Pupil Function: The lens accommodates to focus light; the pupil regulates light entry. 6. Refractive Errors: Myopia, hyperopia, presbyopia, and astigmatism are common refractive errors. 7. Visual Impairment: Ranges from low vision to legal blindness. 8. Cataracts: Lens opacity requiring surgical removal. 9. Retinopathy: Microvascular damage to the retina (diabetic, hypertensive). 10. Retinal Detachment: Separation of the retina, requiring surgical repair. 11. Macular Degeneration: Leading cause of central vision loss in older adults (dry, wet forms). 12. Glaucoma: Increased IOP, optic nerve damage, peripheral vision loss (POAG, PACG). 13. Conductive Hearing Loss: Outer or middle ear problems impair sound transmission. 14. Sensorineural Hearing Loss: Inner ear or nerve damage causes hearing loss. 15. Anemia: Deficiency of erythrocytes, hemoglobin, or hematocrit; various causes and treatments. 16. Hemostasis Disorders: Thrombocytopenia, hemophilia, von Willebrand disease, DIC, neutropenia. 17. Leukemia: Cancer of blood and blood-forming tissues (ALL, AML, CML, CLL). 18. Gastrointestinal System: Ingestion, digestion, absorption, and elimination are key functions. 19. Peptic Ulcer Disease: Erosion of the GI mucosa, often caused by H. pylori. 20. Inflammatory Bowel Disease: Crohn's disease and ulcerative colitis are chronic inflammatory conditions. 21. Colorectal Cancer: Risk factors include age, family history, polyps, and lifestyle factors. 22. Viral Hepatitis: Hepatitis A, B, C, D, and E viruses cause liver inflammation. 23. Cirrhosis: Chronic liver disease leading to liver damage. 24. Pancreatitis: Inflammation of the pancreas (acute, chronic). 25. Cholelithiasis/Cholecystitis: Gallstones and gallbladder inflammation.

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