Pulmonary Pharmacology (2201) - Central Philippine University - Past Paper PDF

**[respiratory diseases and systemic medications]{.smallcaps}** **[pharmacology]{.smallcaps}** - - - - - ------------------------------------------------------- **[specialized aspects of pharmacology]{.smallcaps}** ------------------------------------------------------- - -...

**[respiratory diseases and systemic medications]{.smallcaps}** **[pharmacology]{.smallcaps}** - - - - - ------------------------------------------------------- **[specialized aspects of pharmacology]{.smallcaps}** ------------------------------------------------------- - - - - - - - --------------------------------------- **[types of drug names]{.smallcaps}** --------------------------------------- - - - - - - - - - - - ------------------------------------ **[sources of drugs]{.smallcaps}** ------------------------------------ - - - - - ----------------------------------------------- **[three phases of drug action]{.smallcaps}** ----------------------------------------------- - - - - - Pharmacokinetic phase - Pharmacodynamic phase -------------------------------------------------------------- **[process of drug investigation and approval]{.smallcaps}** -------------------------------------------------------------- - - - - - - - --------------------------------------------------------------- **[pharmaceutical or drug administration phase]{.smallcaps}** --------------------------------------------------------------- - - - - - - - - - - - - - - - - - - - -------------------------------------------------- **[[parenteral route]]{.smallcaps}** -------------------------------------------------- - - - - - - - - -------------------------------------------------- **[methods of topical application]{.smallcaps}** -------------------------------------------------- - - -------------------------------------------- **[[inhalation]]{.smallcaps}** -------------------------------------------- - - - - - - - - - ----------------------------------------- **[pharmacokinetic phase]{.smallcaps}** ----------------------------------------- - - - - - - - - - - ---------------------------------------------------------------- **[major factors controlling the amount of drug]{.smallcaps}** ---------------------------------------------------------------- - - - - a. b. c. d. e. - - - - -  - - - - - ----------------------------------- **[protein binding]{.smallcaps}** ----------------------------------- - - - ------------------------------------ **[pharmacodynamics]{.smallcaps}** ------------------------------------ - - - - - - - ---------------------------------------------- **[drug-receptor interactions]{.smallcaps}** ---------------------------------------------- - - - - -  ------------------------------------- **[drug interactions]{.smallcaps}** ------------------------------------- - - - - - - - - - - - ------------------------------------- **[therapeutic index]{.smallcaps}** ------------------------------------- - - - - **[respiratory disease and medication administered by aerosol inhalation]{.smallcaps}** ----------------------------------------------------------------------------------------- **[respiratory diseases]{.smallcaps}** **[categories of respiratory diseases]{.smallcaps}** ------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- **[categories]{.smallcaps}** **[specific diseases]{.smallcaps}** **Pulmonary infections** Pneumonia, tuberculosis, mycoses **Obstructive lung diseases** Asthma, COPD **Interstitial lung disease** ILD or interstitial lung disease with known causes, ILD or interstitial lung disease with unknown causes **Pleural disease** Pleural effusion, pneumothorax, hydrothorax, pleural tumors **Pulmonary vascular disease** Pulmonary hypertension, pulmonary thromboembolism **Acute lung injury** **Lung cancer** Small cell lung cancer, non-small lung cancers **Neuromuscular and other disease of the chest wall** Disorders of the muscles, disorders of the neuromuscular Junction, disorders of the nerves, disorders of the spinal cord ,disorders of the brain, disorders of the thoracic cage **Disorders of sleep** Obstructive sleep apnea, central sleep apnea **Others** Trauma, obesity, near drowning and burns ----------------------------- **[pneumonia]{.smallcaps}** -----------------------------  -------------------------------- **[tuberculosis]{.smallcaps}** -------------------------------- --------------------------------------------- **[obstructive lung diseases]{.smallcaps}** ---------------------------------------------  ---------------------------------------------------- **[interstitial lung disease or ild]{.smallcaps}** ---------------------------------------------------- - - ------------------------------------ **[pleural diseases]{.smallcaps}** ------------------------------------ ------------------------------------------------------ **[acute respiratory disease syndrome]{.smallcaps}** ------------------------------------------------------  ------------------------------------------------- **[respiratory care pharmacology]{.smallcaps}** ------------------------------------------------- - - - - - - - - - - ------------------------------------------------------------------- **[airway receptors and neural control of the lung]{.smallcaps}** ------------------------------------------------------------------- - - - - - - - - - - - - +-----------------------------------+-----------------------------------+ | **[categories of bronchoactive | | | drugs]{.smallcaps}** | | +===================================+===================================+ | **[categories]{.smallcaps}** | **[examples]{.smallcaps}** | +-----------------------------------+-----------------------------------+ | **Bronchodilators** | **[Ultra-short-acting | | | ]** | | | | | | - | | | | | | **[Short-acting ]** | | | | | | - - - - | | | | | | **[Long-acting ]** | | | | | | - - - - | +-----------------------------------+-----------------------------------+ | **Mucolytic and humidifying | Acetylcysteine | | agents** | | | | Erdosteine | | | | | | Ambroxol | +-----------------------------------+-----------------------------------+ | **Corticosteroids** | Beclomethasone dipropionate | | | | | | Fluticasone propionate | | | | | | Budesonide | | | | | | Hydrocortisone | | | | | | Prednisone | | | | | | Methylprednisolone | +-----------------------------------+-----------------------------------+ | **Surfactant agents** | Colfosceril | | | | | | Beractant | +-----------------------------------+-----------------------------------+ | **Leukotriene antagonists** | Montelukast | | | | | | Zafirlukast | +-----------------------------------+-----------------------------------+ | **Asthma propylactic** | Cromolyn sodium | +-----------------------------------+-----------------------------------+ ------------------------------------------------------------------------------------- **[advantages and disadvantages of aerosolized agents for inhalation]{.smallcaps}** ------------------------------------------------------------------------------------- - - - - - - - - --------------------------------------------------------------------- **[related drug groups important to respiratory care]{.smallcaps}** --------------------------------------------------------------------- - - - - - - - - - - - - - - - - ----------------------------------- **[aerosol therapy]{.smallcaps}** ----------------------------------- - - - - - - - ------------------------------------------------------------------- **[advantages of aerosolized agents for inhalation]{.smallcaps}** ------------------------------------------------------------------- - - - - - - ----------------------------------------------------------------------------- **[disadvantages of the delivery of inhaled aerosols include]{.smallcaps}** ----------------------------------------------------------------------------- - - --------------------------------------------------------------------------------------- **[factors affecting drug powder inhaler performance and drug delivery]{.smallcaps}** --------------------------------------------------------------------------------------- - - - - - - ----------------------------------------------------------- **[characteristics of therapeutic aerosols]{.smallcaps}** ----------------------------------------------------------- - - - - ---------------------------------------------- **[aerosol output measurement]{.smallcaps}** ---------------------------------------------- - - ------------------------------------------------------ **[factors affecting aerosol delivery]{.smallcaps}** ------------------------------------------------------ - - - - - - - -------------------------------------------- **[principles of deposition]{.smallcaps}** -------------------------------------------- - - - - - - - - - - - - - -------------------------------------- **[inertial impaction]{.smallcaps}** -------------------------------------- - - - - - - - - - - - --------------------------------- **[sedimentation]{.smallcaps}** --------------------------------- - - - - - - ----------------------------- **[diffusion]{.smallcaps}** ----------------------------- - - - -  +-----------------------------------+-----------------------------------+ | **[rule of thumb]{.smallcaps}** | | +===================================+===================================+ | The site of deposition in the | | | respiratory tract varies with the | | | size of the particle | | | | | | - | | +-----------------------------------+-----------------------------------+ | Desired location: | Recommended MMAD | | | | | Upper airway | 5 to \>50 μm | | | | | - - - | 2 to 5 μm | | | | | Lower airways | 1--3 μm | | | | | Parenchyma | \ - - - - - - ------------------------------------------------ **[quantifying aerosol delivery]{.smallcaps}** ------------------------------------------------ - - - - - - ---------------------------------------------- **[hazards of aerosol therapy]{.smallcaps}** ---------------------------------------------- - - - - - - ------------------------------------------------- **[aerosol drug delivery systems]{.smallcaps}** ------------------------------------------------- - - - - - - - - - - -