BIO132 Lecture 5 PDF
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Uploaded by CommendableCarnation2866
Alexandria University
Dr. Ahmed Deghidy
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Summary
This document is a lecture on induced pluripotent stem cells. It includes information on the genes responsible for pluripotency, and the applications of stem cells in regenerative medicine.
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Dr. Ahmed Deghidy PhD Molecular Biology Alex U, Alexandria, Egypt Field of Basic Sciences الدولية جامعة العلمين 1 “BIO132” Lecture 5 Dr. Ahmed Deghidy PhD Molecular Biology Alex U, Alexandria, E...
Dr. Ahmed Deghidy PhD Molecular Biology Alex U, Alexandria, Egypt Field of Basic Sciences الدولية جامعة العلمين 1 “BIO132” Lecture 5 Dr. Ahmed Deghidy PhD Molecular Biology Alex U, Alexandria, Egypt Sox2 and Oct4 (which activated Nanog and other transcription factors that established pluripotency and blocked differentiation). c-Myc (which opened up chromatin and made the genes accessible to Sox2, Oct4, and Nanog). Klf4 (which prevents cell death.
