Antacids.docx

Antacids: 1. Mechanism of Action: Neutralization of Gastric Acid: Antacids contain alkaline substances that neutralize gastric acid, raising the pH of the stomach. 2. Drug Effects: Provide rapid relief from heartburn and indigestion. Alleviate symptoms of gastroesophageal reflux disease (GERD). 3. T...

Antacids: 1. Mechanism of Action: Neutralization of Gastric Acid: Antacids contain alkaline substances that neutralize gastric acid, raising the pH of the stomach. 2. Drug Effects: Provide rapid relief from heartburn and indigestion. Alleviate symptoms of gastroesophageal reflux disease (GERD). 3. Therapeutic Uses: Heartburn. Indigestion. GERD. 4. Side Effects and Adverse Effects: Calcium-Containing Antacids: Constipation, hypercalcemia. Magnesium-Containing Antacids: Diarrhea, hypermagnesemia. Aluminum-Containing Antacids: Constipation, potential for aluminum toxicity. Sodium Bicarbonate: Sodium and fluid retention, alkalosis. 5. Toxicity and Management of Overdose: Risk of electrolyte imbalances, especially in patients with renal impairment. Manage with supportive care and correction of electrolyte disturbances. 6. Interactions: Alter absorption of other medications, so they should be taken 1-2 hours apart from other drugs. Magnesium-containing antacids may accumulate in patients with renal impairment. 7. Nursing Responsibilities: Assess for signs of acid-related disorders, such as heartburn. Monitor for adverse effects, especially in patients with renal dysfunction or electrolyte imbalances. Educate patients about proper administration, including timing with other medications. Antacids play a crucial role in providing rapid relief from symptoms of acid-related disorders. Nurses should be vigilant in monitoring for potential side effects, especially in patients with pre-existing renal conditions or those taking other medications. Patient education is essential to ensure proper use and to minimize the risk of interactions with other drugs. Additionally, healthcare providers may consider individual patient factors, such as renal function, when choosing the appropriate type of antacid.