Alkynes Reactions PDF
Document Details
Uploaded by TrendyCarnelian14
Bay Atlantic University
Tags
Summary
These notes provide a comprehensive overview of alkynes reactions, emphasizing their preparation, various addition reactions, and the concept of conjugated dienes. The text includes examples of different reactions and references for further reading on the topic. The notes will be useful for undergraduate students studying organic chemistry.
Full Transcript
Preparation of Alkynes ====================== 22 (2)- By the action of KOH/EtOH on ethylidene chloride (Geminal dihalide): (3)- Using Sodamide in liquid ammonia ------------------------------------- 20 October 2024 23 24 20 October 2024 25 26 (3)- Addition of Cl₂ or Br₂ ---------------------...
Preparation of Alkynes ====================== 22 (2)- By the action of KOH/EtOH on ethylidene chloride (Geminal dihalide): (3)- Using Sodamide in liquid ammonia ------------------------------------- 20 October 2024 23 24 20 October 2024 25 26 (3)- Addition of Cl₂ or Br₂ --------------------------- (4)- Addition of HBr or HCl --------------------------- 20 October 2024 27 3.Conjugated dienes =================== - - 28 - 20 October 2024 29 **Preparation of alkadienes:** 30 Reactions of conjugated dienes ============================== (1)-Addition reaction --------------------- 20 October 2024 31 ### Mechanism 32 1.2-versus 1.4-addition ======================= - - 20 October 2024 33 (2)-Diels Alder reaction (Cycloaddition reaction) ------------------------------------------------- - It is type of 1,2-addition reaction of butadiene proceeding by the cis conformation via a cyclic transition state to yield a cyclic product (Adduct). - The reaction is promoted by the presence of electron withdrawing substituents in the dienophile. 34 20 October 2024 35 +-----------------------------------+-----------------------------------+ | | | +-----------------------------------+-----------------------------------+ | | - Textbook of Organic Medicinal | | | and Pharmaceutical Chemistry, | | | Wilson and Gisvold\'s, 12^th^ | | | Ed., International Edition, | | | Philadelphia : Lippincott | | | Williams & Wilkins, 2011. | | | | | | - Textbook of Organic Medicinal | | | and Pharmaceutical Chemistry, | | | Wilson and Gisvold\'s, 11^th^ | | | Ed., Philadelphia: Lippincott | | | Williams & Wilkins, 2004. | | | | | | - Organic Chemistry ,T. W. | | | Graham Solomons, Craig B. | | | Fryhle, 9^th^ Ed., N.Y.: John | | | Wiley & Sons, Inc., 2006. | | | | | | - Organic Chemistry, T. W. | | | Graham Solomons, Craig B. | | | Fryhle, 8^th^ Ed., N.Y.: John | | | Wiley & Sons, Inc., 2004. | | | | | | - March\'s Advanced Organic | | | Chemistry,: Reactions, | | | Mechanisms, And Structure, | | | Michael B. Smith and Jerry | | | March, 6^th^ Ed., New Jersey | | | : John Wiley and Sons, | | | Inc., 2007. | | | | | | - Organic Chemistry, John | | | McMurry, 7^th^ Ed., Australia | | | : Thomson | +-----------------------------------+-----------------------------------+ | 20 | October 2024 36 | +-----------------------------------+-----------------------------------+
