Canagliflozin (Invokana) - SGLT-2 Inhibitors

Summary

This document describes the prototype drug canagliflozin (Invokana), a type of SGLT-2 inhibitor used in diabetes treatment. Canagliflozin works by lowering blood glucose levels in adults with type 2 diabetes, and it can be added to existing treatment regimens. It often results in weight loss due to its unique feature of glucose excretion in urine.

Full Transcript

**Prototype: canagliflozin (Invokana) ** - **Category: **Sodium-Glucose Cotransporter-2 (SGLT-2) Inhibitors (Oral Hypoglycemic Agent)  - **Primary Function: **SGLT-2 inhibitors lower blood glucose levels in adults with type 2 diabetes by promoting glucose excretion in the urine. Th...

**Prototype: canagliflozin (Invokana) ** - **Category: **Sodium-Glucose Cotransporter-2 (SGLT-2) Inhibitors (Oral Hypoglycemic Agent)  - **Primary Function: **SGLT-2 inhibitors lower blood glucose levels in adults with type 2 diabetes by promoting glucose excretion in the urine. They can also be added to the treatment regimen of clients who are overweight or have a risk of hypoglycemia.  - **Unique Features: **Glycosuria from SGLT-2 inhibitors can also cause weight loss.  - **Example drugs in this class**: - Bexaglifloxin (Brenzavvy™) - Canagliflozin (Invokana®) - Dapagliflozin (Farxiga®) - Empagliflozin (Jardiance®) - Ertugliflozin (Steglatro®)

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