Summary

This document is a presentation or notes on cell membranes. It explains the structure, function, components, and types of proteins found in a cell membrane. The document covers phospholipid bilayers, integral and peripheral proteins, and carbohydrates attached to the cell membrane.

Full Transcript

Cell Membrane Cell Membrane/Plasma Membrane Nickname: “The gatekeeper” Function:  Separates the inside of the cell from the external environment  Controls the flow of material into and out of the cell 2 Cell Membrane/Plasma Membrane  The cell membrane allows only some substances...

Cell Membrane Cell Membrane/Plasma Membrane Nickname: “The gatekeeper” Function:  Separates the inside of the cell from the external environment  Controls the flow of material into and out of the cell 2 Cell Membrane/Plasma Membrane  The cell membrane allows only some substances to pass through it.  Therefore, it is called a “semi-permeable” membrane 3 Cell Membrane/Plasma Membrane  A cell membrane is made up of:  Phospholipid bilayer  Proteins  Carbohydrates  Cholesterol 4 Phospholipid Bilayer  The cell membrane is made up of a double layer of phospholipid molecules  Phospholipid molecules have two different ends:  Hydrophobic tail  Hydrophilic head  Only other small fat soluble molecules can pass through the phospholipids bilayer on their own 5 Phospholipid  Lipid = fat  Hydrophilic – water loving  Hydrophobic – water hating 6 7 The Fluid Mosaic Model  The cell membrane is described to be fluid because of its hydrophobic integral components such as lipids and membrane proteins that move laterally or sideways throughout the membrane.  That means the membrane is not solid, but more like a 'fluid'. 8 The Fluid Mosaic Model  The membrane is depicted as mosaic because it is like a mosaic that is made up of many different parts  The cell membrane is composed of different kinds of macromolecules, such as proteins and carbohydrates 9 Proteins of the Cell Membrane  These proteins are like “doorways” in the cell membrane.  They let molecules pass through the cell membrane that are not able to pass directly through the phospholipid bilayer.  That is, they let larger molecules and non- fat soluble molecules move in and out of the cell.  Transport can either be passive (no energy required) or active (requires energy) 10 Types of Cellular Proteins 1) Integral Proteins  Imbedded within the bilayer, often going from one side to the other  Help with the transport of larger or polar (charged) molecules through the membrane  Two types : Carrier and Channel Channel = open tube, usually passive transport Carrier = picked up and spit out, usually active transport Types of proteins Con… 2) Peripheral Proteins  Bound to the surface of the bilayer (either inside or out)  Can detach and attach depending on the need of the cell  Help with cell signaling, act as enzymes, and help provide shape/structure Carbohydrates of the Cell Membrane  These are long chains of carbohydrates that are attached to the outside of the cell membrane  Carbohydrates help cells recognize other cells and they help cells stick to other cells  Glycoprotein – a protein with a carbohydrate attached to it  Glycolipid – a lipid with a carbohydrate attached to it 14 Fats in the cell membrane Cholesterol (Steroid)  Embedded in the phospholipid bilayer  Helps keep fluidity of membrane consistent  Reduces fluidity at high temperatures  Increases fluidity of membrane at low temperatures  Acts as a membrane “antifreeze agent” 15 16

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