With a sufficiently long duration pulse, there is time for the membrane capacitance to .......... and the change in membrane potential is maximum.

Understand the Problem

The question is asking about the physiological understanding of membrane capacitance in relation to a pulse duration and its effect on membrane potential change. The responder must identify the correct completion of the statement given the context of membrane capacitance.

More Information

When a membrane capacitance has time to charge during a long-duration pulse, it allows the maximum change in membrane potential to occur.

Tips

A common mistake is confusing 'charge' with 'discharge'; the context of the pulse duration indicates charging.

Sources

• Electrophysiology Fundamentals, Membrane Potential and... - technologynetworks.com