Which is the best method for the synthesis of tert-butyl methyl ether?
Understand the Problem
The question is asking which method is the best for synthesizing tert-butyl methyl ether. It presents multiple chemical reactions and asks to identify the most effective one among the options given.
Answer
(CH3)3CONa + CH3I
The best method for the synthesis of tert-butyl methyl ether is (b) (CH3)3CONa + CH3I.
Answer for screen readers
The best method for the synthesis of tert-butyl methyl ether is (b) (CH3)3CONa + CH3I.
More Information
The reaction between tert-butoxide ion and iodomethane is the best method because it minimizes steric hindrance and maximizes reaction success via the SN2 mechanism.
Tips
A common mistake is choosing a reaction with bulky reactants that hinders the SN2 mechanism.
Sources
- Ethers and Epoxides - Organic Chemistry - chem.libretexts.org
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