What is often the cause of defective antibody responses in conditions like X-linked agammaglobulinemia?
Understand the Problem
The question is asking for the specific cause of defective antibody responses in conditions such as X-linked agammaglobulinemia, and it provides multiple choice options to choose from.
Answer
Mutations in the BTK gene on the X chromosome.
Defective antibody responses in conditions like X-linked agammaglobulinemia are often caused by mutations in the BTK gene located on the X chromosome.
Answer for screen readers
Defective antibody responses in conditions like X-linked agammaglobulinemia are often caused by mutations in the BTK gene located on the X chromosome.
More Information
The BTK gene provides instructions for making a protein that is necessary for the development and maturation of B cells, which are crucial for the production of antibodies. Deficiencies in these processes can lead to increased susceptibility to infections.
Tips
A common mistake is overlooking other potential causes or contributors to immune deficiencies, such as environmental factors or other genetic conditions.
Sources
- X-Linked Agammaglobulinemia: Causes, Symptoms & Treatment - my.clevelandclinic.org
- Autoimmunity and Inflammation in X-linked Agammaglobulinemia - pmc.ncbi.nlm.nih.gov
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