In the context of signal transduction pathways, what is the most accurate description of the term 'receptor-effector coupling mechanism'?
Understand the Problem
The question asks for the best definition of 'receptor-effector coupling mechanism' within the context of signal transduction pathways. This refers to how a receptor, once activated by a signal (ligand), initiates a downstream effect in the cell. The options offer different interpretations, and the best choice encapsulates the complete process of signal transfer from the receptor to the cellular response.
Answer
Receptor-effector coupling is how a receptor activates a downstream effector, directly or indirectly, to trigger a cellular response.
Receptor-effector coupling describes how a receptor activates a downstream effector, either directly or indirectly, to produce a cellular response. This process often involves intermediate molecules like G proteins or other intracellular signals.
Answer for screen readers
Receptor-effector coupling describes how a receptor activates a downstream effector, either directly or indirectly, to produce a cellular response. This process often involves intermediate molecules like G proteins or other intracellular signals.
More Information
Receptor-effector coupling is a crucial step in signal transduction, ensuring that the initial signal received by the receptor leads to a specific and appropriate cellular response. The efficiency and specificity of this coupling are vital for maintaining cellular function and responding to environmental changes.
Tips
Confusing receptor-effector coupling with just receptor activation. The coupling includes the downstream events leading to a cellular response, not just the initial binding.
Sources
- Signal Transduction - an overview | ScienceDirect Topics - sciencedirect.com
- Pathways of Intracellular Signal Transduction - The Cell - NCBI - ncbi.nlm.nih.gov
- Receptor–effector coupling | physiology - Britannica - britannica.com
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