Understand the Problem
The document discusses glucose-6-phosphate dehydrogenase (G6PD) deficiency, its genetic inheritance, effects on glucose metabolism, and its association with specific ethnic groups and malaria. It also mentions historical findings related to this enzyme deficiency.
Answer
G6PD deficiency causes oxidative stress vulnerability and red cell hemolysis.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked genetic disorder leading to decreased NADPH production and vulnerability to oxidative stress, causing hemolysis of red blood cells.
Answer for screen readers
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked genetic disorder leading to decreased NADPH production and vulnerability to oxidative stress, causing hemolysis of red blood cells.
More Information
The deficiency is more common in specific populations and can protect against severe malaria. It primarily affects males due to its X-linked inheritance.
Tips
A common mistake is not accounting for X-linked inheritance affecting males differently from females.
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