Explain the composition of intermediate filaments.
Understand the Problem
The question is asking for an explanation of the structure and components of intermediate filaments, which are important cytoskeletal elements in cells. The response will involve discussing the types of proteins that make up these filaments and their roles in cellular function.
Answer
Intermediate filaments consist of protein subunits like keratins, coded by multiple genes and grouped into types I-VI based on protein structure.
Intermediate filaments are composed of different protein subunits, including keratins, which are coded by 70 different genes. These protein subunits are grouped into types I to VI based on their amino acid sequence and structure. They share a common α-helical rod domain.
Answer for screen readers
Intermediate filaments are composed of different protein subunits, including keratins, which are coded by 70 different genes. These protein subunits are grouped into types I to VI based on their amino acid sequence and structure. They share a common α-helical rod domain.
More Information
Intermediate filaments are critical for maintaining the structural integrity and resilience of cells, providing a scaffold that supports cell shape and mechanical resistance.
Tips
A common mistake is confusing intermediate filaments with other cytoskeletal components like microfilaments or microtubules, which have distinct structures and functions.
Sources
- Intermediate filament - Wikipedia - en.wikipedia.org
- The Cell - NCBI Bookshelf - ncbi.nlm.nih.gov
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